Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:endothelin receptor signaling pathway
go back to main search page
Accession:GO:0086100 term browser browse the term
Definition:A series of molecular signals initiated by an endothelin receptor binding to one of its physiological ligands, and proceeding with the activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. Ends with regulation of a downstream cellular process, e.g. transcription.
Synonyms:related_synonym: endothelin signaling pathway


show annotations for term's descendants           Sort by:
 
endothelin receptor signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcar1 BCAR1 scaffold protein, Cas family member ISO
IEA
ISS
(PMID:19086031)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:19086031 GO_REF:0000024, GO_REF:0000107 NCBI chr19:43,932,543...43,967,452
Ensembl chr19:43,932,554...43,955,783
JBrowse link
G Bcar3 BCAR3 adaptor protein, NSP family member IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 2:226,563,050...226,679,449
Ensembl chr 2:226,563,050...226,679,438
JBrowse link
G Crkl CRK like proto-oncogene, adaptor protein ISO MGI:5510713 (MGI:6102264|PMID:25565927) RGD PMID:25565927 MGI:6102264 NCBI chr11:87,338,606...87,356,644
Ensembl chr11:87,778,312...87,815,043
JBrowse link
G Dear dual endothelin 1, angiotensin II receptor IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 2:184,243,976...184,247,228
Ensembl chr 2:184,243,976...184,247,228
JBrowse link
G Edn1 endothelin 1 ISO
ISS
(PMID:19086031)
GO_REF:0000024
RGD
UniProt
PMID:19086031 GO_REF:0000024 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324
JBrowse link
G Ednra endothelin receptor type A IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr19:33,928,356...33,991,703
Ensembl chr19:33,928,356...33,991,703
JBrowse link
G Ednrb endothelin receptor type B ISO (PMID:1713452), (PMID:19767294), (PMID:28236341) RGD PMID:1713452, PMID:19767294, PMID:28236341 NCBI chr15:88,004,775...88,036,354
Ensembl chr15:88,006,977...88,036,354
JBrowse link
G Ptk2b protein tyrosine kinase 2 beta ISO
ISS
(PMID:19086031)
GO_REF:0000024
RGD
UniProt
PMID:19086031 GO_REF:0000024 NCBI chr15:42,827,306...42,947,796
Ensembl chr15:42,827,310...42,947,656
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20020
    signaling 7579
      signal transduction 7010
        G protein-coupled receptor signaling pathway 2509
          endothelin receptor signaling pathway 8
            endothelin receptor signaling pathway involved in heart process 0
Path 2
Term Annotations click to browse term
  biological_process 20020
    biological regulation 13769
      regulation of biological process 13071
        regulation of cellular process 12556
          signal transduction 7010
            G protein-coupled receptor signaling pathway 2509
              endothelin receptor signaling pathway 8
                endothelin receptor signaling pathway involved in heart process 0
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.