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ONTOLOGY REPORT - ANNOTATIONS


Term:endothelin receptor signaling pathway
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Accession:GO:0086100 term browser browse the term
Definition:A series of molecular signals initiated by an endothelin receptor binding to one of its physiological ligands, and proceeding with the activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. Ends with regulation of a downstream cellular process, e.g. transcription.
Synonyms:related_synonym: endothelin signaling pathway


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endothelin receptor signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Crkl CRK like proto-oncogene, adaptor protein JBrowse link 11 87,338,606 87,356,644 RGD:1600115
RGD:1624291
G Dear dual endothelin 1, angiotensin II receptor JBrowse link 2 184,243,976 184,247,228 RGD:1600115
G Ednra endothelin receptor type A JBrowse link 19 33,928,356 33,991,703 RGD:1600115
G Ednrb endothelin receptor type B JBrowse link 15 88,004,775 88,036,354 RGD:1624291
RGD:1600115
G LOC100911248 crk-like protein-like JBrowse link 11 87,778,338 87,815,049 RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18166
    signaling 7108
      signal transduction 6597
        G protein-coupled receptor signaling pathway 2395
          endothelin receptor signaling pathway 5
            endothelin receptor signaling pathway involved in heart process 0
Path 2
Term Annotations click to browse term
  biological_process 18166
    biological regulation 12793
      regulation of biological process 12128
        regulation of cellular process 11458
          signal transduction 6597
            G protein-coupled receptor signaling pathway 2395
              endothelin receptor signaling pathway 5
                endothelin receptor signaling pathway involved in heart process 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.