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ONTOLOGY REPORT - ANNOTATIONS


Term:primitive streak formation
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Accession:GO:0090009 term browser browse the term
Definition:The developmental process pertaining to the initial formation of the primitive streak from unspecified parts. The primitive streak is a ridge of cells running along the midline of the embryo where the mesoderm ingresses. It defines the anterior-posterior axis.


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primitive streak formation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ets2 ETS proto-oncogene 2, transcription factor ISO MGI:1891557 (MGI:5546318|PMID:23552073) RGD PMID:23552073 MGI:5546318 NCBI chr11:36,075,709...36,092,495
Ensembl chr11:36,075,709...36,092,495
JBrowse link
G Foxa2 forkhead box A2 ISS
ISO
GO_REF:0000024
MGI:1857725 (MGI:2157654|PMID:11291865)
UniProt
RGD
PMID:11291865 GO_REF:0000024, MGI:2157654 NCBI chr 3:142,383,084...142,387,493
Ensembl chr 3:142,383,278...142,387,481
JBrowse link
G Gdf3 growth differentiation factor 3 ISO MGI:3612535 (MGI:3611720|PMID:16368929) RGD PMID:16368929 MGI:3611720 NCBI chr 4:155,417,667...155,422,014
Ensembl chr 4:155,417,004...155,421,998
JBrowse link
G Hhex hematopoietically expressed homeobox ISO MGI:4999724|MGI:97359 (MGI:4950786|PMID:21445260) RGD PMID:21445260 MGI:4950786 NCBI chr 1:256,101,994...256,107,581
Ensembl chr 1:256,101,903...256,107,649
JBrowse link
G Lhx1 LIM homeobox 1 ISS
ISO
GO_REF:0000024
MGI:1857502|MGI:1857848 (MGI:2157654|PMID:11291865)
UniProt
RGD
PMID:11291865 GO_REF:0000024, MGI:2157654 NCBI chr10:71,843,991...71,849,293
Ensembl chr10:71,843,991...71,849,293
JBrowse link
G Lrp6 LDL receptor related protein 6 IBA
ISO
PMID:21873635
MGI:98958 (MGI:4413372|PMID:19795512)
RGD PMID:19795512, PMID:21873635 MGI:4413372, RGD:13792537 NCBI chr 4:168,194,054...168,323,962
Ensembl chr 4:168,194,927...168,323,751
JBrowse link
G Nodal nodal growth differentiation factor ISO MGI:96086 (MGI:4950786|PMID:21445260) RGD PMID:21445260 MGI:4950786 NCBI chr20:31,035,729...31,044,096
Ensembl chr20:31,035,729...31,044,096
JBrowse link
G Otx2 orthodenticle homeobox 2 ISO MGI:1857502 (MGI:2157654|PMID:11291865) RGD PMID:11291865 MGI:2157654 NCBI chr15:25,500,037...25,511,619
Ensembl chr15:25,502,019...25,505,691
JBrowse link
G Srf serum response factor ISO MGI:2158696 (MGI:1312998|PMID:9799237) RGD PMID:9799237 MGI:1312998 NCBI chr 9:16,737,637...16,747,226
Ensembl chr 9:16,737,642...16,747,225
JBrowse link
G Wnt5a Wnt family member 5A IEA
ISO
GO_REF:0000107
MGI:1298218 (MGI:4413372|PMID:19795512)
Ensembl
RGD
PMID:19795512 GO_REF:0000107, MGI:4413372 NCBI chr16:4,469,451...4,490,271
Ensembl chr16:4,469,468...4,489,860
JBrowse link
transforming growth factor beta receptor signaling pathway involved in primitive streak formation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nodal nodal growth differentiation factor ISO (MGI:2677178|PMID:14511481) RGD PMID:14511481 MGI:2677178 NCBI chr20:31,035,729...31,044,096
Ensembl chr20:31,035,729...31,044,096
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20020
    developmental process 6826
      anatomical structure formation involved in morphogenesis 1214
        primitive streak formation 10
          Wnt signaling pathway involved in primitive streak formation 0
          transforming growth factor beta receptor signaling pathway involved in primitive streak formation + 1
Path 2
Term Annotations click to browse term
  biological_process 20020
    developmental process 6826
      anatomical structure development 6268
        multicellular organism development 5743
          embryo development 1307
            embryonic morphogenesis 690
              gastrulation 208
                gastrulation with mouth forming second 39
                  primitive streak formation 10
                    Wnt signaling pathway involved in primitive streak formation 0
                    transforming growth factor beta receptor signaling pathway involved in primitive streak formation + 1
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.