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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of protein kinase C signaling
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Accession:GO:0090038 term browser browse the term
Definition:Any process that decreases the frequency, rate, or extent of a series of reactions, mediated by the intracellular serine/threonine kinase protein kinase C, which occurs as a result of a single trigger reaction or compound.
Synonyms:related_synonym: negative regulation of protein kinase C signaling cascade;   negative regulation of protein kinase C signalling cascade


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negative regulation of protein kinase C signaling term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DGKD diacylglycerol kinase delta ISO (MGI:MGI:3691361|PMID:17021016) UniProt PMID:17021016 MGI:MGI:3691361 NCBI chr2B:120,582,278...120,701,165
Ensembl chr2B:239,525,401...239,611,873
JBrowse link
G DGKG diacylglycerol kinase gamma ISO (MGI:MGI:6431961|PMID:32033984) UniProt PMID:32033984 MGI:MGI:6431961 NCBI chr 3:183,164,835...183,392,282
Ensembl chr 3:191,632,892...191,860,807
JBrowse link
G GPD1L glycerol-3-phosphate dehydrogenase 1 like ISO (PMID:19666841) BHF-UCL PMID:19666841 NCBI chr 3:32,026,586...32,088,512
Ensembl chr 3:32,342,776...32,404,172
JBrowse link
G MYADM myeloid associated differentiation marker ISO (PMID:23264465) UniProtKB PMID:23264465 NCBI chr19:50,807,615...50,817,196
Ensembl chr19:59,663,790...59,664,758
JBrowse link
G PHLPP1 PH domain and leucine rich repeat protein phosphatase 1 ISO RGD PMID:20819118 RGD:8693633 NCBI chr18:56,084,851...56,338,551 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12524
    negative regulation of biological process 4849
      negative regulation of signaling 1314
        negative regulation of signal transduction 1159
          negative regulation of intracellular signal transduction 512
            negative regulation of protein kinase C signaling 5
Path 2
Term Annotations click to browse term
  biological_process 12524
    biological regulation 9129
      regulation of biological process 8652
        regulation of cellular process 8181
          signal transduction 3809
            intracellular signal transduction 2043
              protein kinase C signaling 37
                regulation of protein kinase C signaling 19
                  negative regulation of protein kinase C signaling 5
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.