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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of protein kinase C signaling
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Accession:GO:0090038 term browser browse the term
Definition:Any process that decreases the frequency, rate, or extent of a series of reactions, mediated by the intracellular serine/threonine kinase protein kinase C, which occurs as a result of a single trigger reaction or compound.
Synonyms:related_synonym: negative regulation of protein kinase C signaling cascade;   negative regulation of protein kinase C signalling cascade


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negative regulation of protein kinase C signaling term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dgkd diacylglycerol kinase delta ISO (MGI:MGI:3691361|PMID:17021016) UniProt PMID:17021016 MGI:MGI:3691361 NCBI chrNW_004955453:2,740,922...2,802,669 JBrowse link
G Dgkg diacylglycerol kinase gamma ISO (MGI:MGI:6431961|PMID:32033984) UniProt PMID:32033984 MGI:MGI:6431961 NCBI chrNW_004955420:21,296,515...21,481,651 JBrowse link
G Gpd1l glycerol-3-phosphate dehydrogenase 1 like ISO (PMID:19666841) BHF-UCL PMID:19666841 NCBI chrNW_004955430:23,481,957...23,536,407 JBrowse link
G Myadm myeloid associated differentiation marker ISO (PMID:23264465) UniProtKB PMID:23264465 NCBI chrNW_004955604:280,977...284,381 JBrowse link
G Phlpp1 PH domain and leucine rich repeat protein phosphatase 1 ISO RGD PMID:20819118 RGD:8693633 NCBI chrNW_004955402:46,563,918...46,773,349 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 11857
    negative regulation of biological process 4623
      negative regulation of signaling 1279
        negative regulation of signal transduction 1128
          negative regulation of intracellular signal transduction 497
            negative regulation of protein kinase C signaling 5
Path 2
Term Annotations click to browse term
  biological_process 11857
    biological regulation 8688
      regulation of biological process 8250
        regulation of cellular process 7832
          signal transduction 3673
            intracellular signal transduction 1974
              protein kinase C signaling 36
                regulation of protein kinase C signaling 19
                  negative regulation of protein kinase C signaling 5
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.