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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of protein kinase C signaling
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Accession:GO:0090038 term browser browse the term
Definition:Any process that decreases the frequency, rate, or extent of a series of reactions, mediated by the intracellular serine/threonine kinase protein kinase C, which occurs as a result of a single trigger reaction or compound.
Synonyms:related_synonym: negative regulation of protein kinase C signaling cascade;   negative regulation of protein kinase C signalling cascade


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negative regulation of protein kinase C signaling term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dgkd diacylglycerol kinase, delta ISO
IEA
(MGI:MGI:3691361|PMID:17021016)
GO_REF:0000107
RGD
Ensembl
PMID:17021016 GO_REF:0000107, MGI:MGI:3691361 NCBI chr 9:94,980,328...95,071,531
Ensembl chr 9:94,980,409...95,069,714
JBrowse link
G Dgkg diacylglycerol kinase, gamma ISS
ISO
GO_REF:0000024
(MGI:MGI:6431961|PMID:32033984)
UniProt
RGD
PMID:32033984 GO_REF:0000024, MGI:MGI:6431961 NCBI chr11:81,971,585...82,165,111
Ensembl chr11:81,972,219...82,163,165
JBrowse link
G Gpd1l glycerol-3-phosphate dehydrogenase 1-like ISO (PMID:19666841) RGD PMID:19666841 NCBI chr 8:122,957,570...122,987,236
Ensembl chr 8:122,954,948...122,987,191
JBrowse link
G Myadm myeloid-associated differentiation marker ISO (PMID:23264465) RGD PMID:23264465 NCBI chr 1:64,438,465...64,448,332
Ensembl chr 1:64,438,472...64,446,818
JBrowse link
G Phlpp1 PH domain and leucine rich repeat protein phosphatase 1 IMP RGD PMID:20819118 RGD:8693633 NCBI chr13:26,145,989...26,394,505
Ensembl chr13:26,172,243...26,394,505
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20017
    negative regulation of biological process 5710
      negative regulation of signaling 1403
        negative regulation of signal transduction 1243
          negative regulation of intracellular signal transduction 551
            negative regulation of protein kinase C signaling 5
Path 2
Term Annotations click to browse term
  biological_process 20017
    biological regulation 13767
      regulation of biological process 13081
        regulation of cellular process 12570
          signal transduction 7015
            intracellular signal transduction 2615
              protein kinase C signaling 39
                regulation of protein kinase C signaling 21
                  negative regulation of protein kinase C signaling 5
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.