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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of heart induction by negative regulation of canonical Wnt signaling pathway
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Accession:GO:0090082 term browser browse the term
Definition:Any process that decreases the rate, frequency or extent of canonical Wnt signaling pathway that positively regulates heart induction. Canonical Wnt signaling pathway involved in heart induction is the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.
Synonyms:exact_synonym: positive regulation of heart induction by negative regulation of canonical Wnt receptor signaling pathway;   positive regulation of heart induction by negative regulation of canonical Wnt receptor signalling pathway;   positive regulation of heart induction by negative regulation of canonical Wnt-activated signaling pathway


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positive regulation of heart induction by negative regulation of canonical Wnt signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 ISO (MGI:3835736|PMID:18297060) RGD PMID:18297060 MGI:3835736 NCBI chr 1:248,952,896...248,956,579
Ensembl chr 1:248,895,738...248,898,607
JBrowse link
G Mesp1 mesoderm posterior bHLH transcription factor 1 ISO (MGI:3835736|PMID:18297060) RGD PMID:18297060 MGI:3835736 NCBI chr 1:141,532,390...141,533,908
Ensembl chr 1:141,532,390...141,533,908
JBrowse link
G Wnt11 Wnt family member 11 ISO UniProtKB:P22725 (MGI:5424267|PMID:22569553) RGD PMID:22569553 MGI:5424267 NCBI chr 1:163,794,136...163,813,756
Ensembl chr 1:163,797,660...163,813,756
JBrowse link
G Wnt5a Wnt family member 5A IEA
ISO
GO_REF:0000107
UniProtKB:P48615 (MGI:5424267|PMID:22569553)
Ensembl
RGD
PMID:22569553 GO_REF:0000107, MGI:5424267 NCBI chr16:4,469,451...4,490,271
Ensembl chr16:4,469,468...4,489,860
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20020
    developmental process 6826
      negative regulation of developmental process 1015
        negative regulation of Wnt signaling pathway involved in heart development 8
          positive regulation of heart induction by negative regulation of canonical Wnt signaling pathway 4
Path 2
Term Annotations click to browse term
  biological_process 20020
    developmental process 6826
      anatomical structure development 6268
        multicellular organism development 5743
          system development 5279
            animal organ development 4033
              animal organ morphogenesis 1151
                animal organ formation 76
                  regulation of animal organ formation 34
                    organ induction 29
                      heart induction 11
                        regulation of heart induction 6
                          regulation of heart induction by canonical Wnt signaling pathway 6
                            regulation of heart induction by regulation of canonical Wnt signaling pathway 5
                              positive regulation of heart induction by negative regulation of canonical Wnt signaling pathway 4
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.