ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of sphingolipid biosynthetic process
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Accession:GO:0090153 term browser browse the term
Definition:Any process that modulates the rate, frequency or extent of sphingolipid biosynthesis. Sphingolipid biosynthesis is the chemical reactions and pathways resulting in the formation of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid).


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negative regulation of ceramide biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ormdl1 ORMDL sphingolipid biosynthesis regulator 1 JBrowse link 9 53,110,628 53,120,454 RGD:1624291
RGD:13792537
G Ormdl2 ORMDL sphingolipid biosynthesis regulator 2 JBrowse link 7 3,242,991 3,246,085 RGD:1624291
RGD:13792537
G Ormdl3 ORMDL sphingolipid biosynthesis regulator 3 JBrowse link 10 86,545,910 86,554,478 RGD:1624291
RGD:13792537
RGD:1600115
G Sphk1 sphingosine kinase 1 JBrowse link 10 105,498,728 105,504,401 RGD:1600115
RGD:1624291
negative regulation of sphingolipid biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atg7 autophagy related 7 JBrowse link 4 146,570,113 146,777,093 RGD:1624291
positive regulation of ceramide biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ccn1 cellular communication network factor 1 JBrowse link 2 251,529,354 251,532,312 RGD:1624291
RGD:1600115
G Pla2g6 phospholipase A2 group VI JBrowse link 7 120,519,479 120,559,716 RGD:6482750
G Prkcd protein kinase C, delta JBrowse link 16 6,655,131 6,675,746 RGD:1624291
RGD:1600115
G Smpd3 sphingomyelin phosphodiesterase 3 JBrowse link 19 38,237,963 38,321,572 RGD:10041064
G Sphk2 sphingosine kinase 2 JBrowse link 1 101,692,972 101,700,604 RGD:1600115
RGD:1624291
regulation of ceramide biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Samd8 sterile alpha motif domain containing 8 JBrowse link 15 2,685,504 2,731,062 RGD:1624291
RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17928
    regulation of biological process 11965
      regulation of cellular component biogenesis 972
        regulation of sphingolipid biosynthetic process 11
          negative regulation of sphingolipid biosynthetic process + 5
          positive regulation of sphingolipid biosynthetic process + 5
          regulation of ceramide biosynthetic process + 10
Path 2
Term Annotations click to browse term
  biological_process 17928
    metabolic process 10678
      primary metabolic process 9619
        lipid metabolic process 1258
          cellular lipid metabolic process 959
            membrane lipid metabolic process 172
              sphingolipid metabolic process 125
                sphingolipid biosynthetic process 77
                  regulation of sphingolipid biosynthetic process 11
                    negative regulation of sphingolipid biosynthetic process + 5
                    positive regulation of sphingolipid biosynthetic process + 5
                    regulation of ceramide biosynthetic process + 10
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.