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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of sphingolipid biosynthetic process
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Accession:GO:0090155 term browser browse the term
Definition:Any process that decreases the rate, frequency or extent of sphingolipid biosynthesis. Sphingolipid biosynthesis is the chemical reactions and pathways resulting in the formation of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid).
Synonyms:related_synonym: negative regulation of sphingolipid biosynthesis involved in cellular sphingolipid homeostasis
 alt_id: GO:0090157


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negative regulation of sphingolipid biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abca2 ATP binding cassette subfamily A member 2 JBrowse link 3 2,648,787 2,668,770 RGD:1624291
RGD:14697729
RGD:1600115
G Atg7 autophagy related 7 JBrowse link 4 146,570,113 146,777,093 RGD:1624291
negative regulation of ceramide biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ormdl1 ORMDL sphingolipid biosynthesis regulator 1 JBrowse link 9 53,110,628 53,120,454 RGD:1624291
RGD:13792537
G Ormdl2 ORMDL sphingolipid biosynthesis regulator 2 JBrowse link 7 3,242,991 3,246,085 RGD:1624291
RGD:13792537
G Ormdl3 ORMDL sphingolipid biosynthesis regulator 3 JBrowse link 10 86,545,910 86,554,478 RGD:1624291
RGD:13792537
RGD:1600115
G Sphk1 sphingosine kinase 1 JBrowse link 10 105,498,728 105,504,401 RGD:1600115
RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19858
    metabolic process 12097
      nitrogen compound metabolic process 10193
        negative regulation of nitrogen compound metabolic process 2504
          negative regulation of sphingolipid biosynthetic process 6
            negative regulation of ceramide biosynthetic process + 4
Path 2
Term Annotations click to browse term
  biological_process 19858
    metabolic process 12097
      primary metabolic process 10750
        lipid metabolic process 1363
          cellular lipid metabolic process 1043
            membrane lipid metabolic process 187
              sphingolipid metabolic process 137
                sphingolipid biosynthetic process 85
                  regulation of sphingolipid biosynthetic process 14
                    negative regulation of sphingolipid biosynthetic process 6
                      negative regulation of ceramide biosynthetic process + 4
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.