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ONTOLOGY REPORT - ANNOTATIONS


Term:planar cell polarity pathway involved in neural tube closure
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Accession:GO:0090179 term browser browse the term
Definition:The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors that modulates the establishment of planar polarity contributing to neural tube closure.


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planar cell polarity pathway involved in neural tube closure term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Celsr1 cadherin, EGF LAG seven-pass G-type receptor 1 JBrowse link 15 85,898,758 86,034,217 RGD:2290270
G Dvl1 dishevelled segment polarity protein 1 JBrowse link 4 155,847,317 155,859,303 RGD:2290270
G Dvl2 dishevelled segment polarity protein 2 JBrowse link 11 70,000,626 70,010,109 RGD:2290270
G Dvl3 dishevelled segment polarity protein 3 JBrowse link 16 20,516,937 20,534,013 RGD:2290270
G Fzd1 frizzled class receptor 1 JBrowse link 5 4,753,839 4,758,216 RGD:2290270
G Fzd2 frizzled class receptor 2 JBrowse link 11 102,604,431 102,608,058 RGD:2290270
G Grhl3 grainyhead like transcription factor 3 JBrowse link 4 135,541,887 135,573,625 RGD:2290270
G Ptk7 PTK7 protein tyrosine kinase 7 JBrowse link 17 46,564,451 46,630,049 RGD:2290270
G Sfrp1 secreted frizzled-related protein 1 JBrowse link 8 23,411,382 23,449,632 RGD:2290270
G Sfrp2 secreted frizzled-related protein 2 JBrowse link 3 83,766,158 83,774,314 RGD:2290270
G Sfrp5 secreted frizzled-related sequence protein 5 JBrowse link 19 42,197,971 42,202,252 RGD:2290270
G Vangl2 VANGL planar cell polarity 2 JBrowse link 1 172,000,960 172,027,314 RGD:2290270
G Wnt5a wingless-type MMTV integration site family, member 5A JBrowse link 14 28,505,473 28,527,448 RGD:2290270
negative regulation of planar cell polarity pathway involved in neural tube closure term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lrp6 low density lipoprotein receptor-related protein 6 JBrowse link 6 134,446,476 134,567,018 RGD:2290270

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 22981
    developmental process 6216
      anatomical structure formation involved in morphogenesis 1156
        tube formation 174
          tube closure 110
            neural tube closure 109
              planar cell polarity pathway involved in neural tube closure 14
                negative regulation of planar cell polarity pathway involved in neural tube closure 1
                regulation of planar cell polarity pathway involved in neural tube closure + 1
Path 2
Term Annotations click to browse term
  biological_process 22981
    developmental process 6216
      anatomical structure development 5828
        multicellular organism development 5323
          tube development 1120
            tube morphogenesis 904
              tube formation 174
                epithelial tube formation 159
                  embryonic epithelial tube formation 153
                    neural tube formation 131
                      primary neural tube formation 116
                        neural tube closure 109
                          establishment of planar polarity involved in neural tube closure 16
                            regulation of establishment of planar polarity involved in neural tube closure 15
                              planar cell polarity pathway involved in neural tube closure 14
                                negative regulation of planar cell polarity pathway involved in neural tube closure 1
                                regulation of planar cell polarity pathway involved in neural tube closure + 1
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.