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ONTOLOGY REPORT - ANNOTATIONS


Term:planar cell polarity pathway involved in neural tube closure
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Accession:GO:0090179 term browser browse the term
Definition:The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors that modulates the establishment of planar polarity contributing to neural tube closure.


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planar cell polarity pathway involved in neural tube closure term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Celsr1 cadherin EGF LAG seven-pass G-type receptor 1 JBrowse link NW_004936629 3,453,384 3,570,250 RGD:9068941
G Dvl1 dishevelled segment polarity protein 1 JBrowse link NW_004936737 1,797,348 1,811,043 RGD:9068941
G Dvl2 dishevelled segment polarity protein 2 JBrowse link NW_004936595 520,299 528,361 RGD:9068941
G Dvl3 dishevelled segment polarity protein 3 JBrowse link NW_004936578 5,693,433 5,710,137 RGD:9068941
G Fzd1 frizzled class receptor 1 JBrowse link NW_004936621 2,899,183 2,903,427 RGD:9068941
G Fzd2 frizzled class receptor 2 JBrowse link NW_004936541 965,135 967,018 RGD:9068941
G Grhl3 grainyhead like transcription factor 3 JBrowse link NW_004936474 9,321,754 9,354,486 RGD:9068941
G Ptk7 protein tyrosine kinase 7 (inactive) JBrowse link NW_004936476 16,797,836 16,866,989 RGD:9068941
G Sfrp1 secreted frizzled related protein 1 JBrowse link NW_004936785 1,276,478 1,320,397 RGD:9068941
G Sfrp2 secreted frizzled related protein 2 JBrowse link NW_004936576 604,174 612,440 RGD:9068941
G Vangl2 VANGL planar cell polarity protein 2 JBrowse link NW_004936740 228,377 242,318 RGD:9068941
G Wnt5a Wnt family member 5A JBrowse link NW_004936473 6,031,627 6,052,211 RGD:9068941
regulation of planar cell polarity pathway involved in neural tube closure term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nphp3 nephrocystin 3 JBrowse link NW_004936529 6,013,321 6,048,249 RGD:9068941

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 14725
    developmental process 5760
      anatomical structure formation involved in morphogenesis 1062
        tube formation 149
          tube closure 94
            neural tube closure 93
              planar cell polarity pathway involved in neural tube closure 13
                negative regulation of planar cell polarity pathway involved in neural tube closure 0
                regulation of planar cell polarity pathway involved in neural tube closure + 1
Path 2
Term Annotations click to browse term
  biological_process 14725
    developmental process 5760
      anatomical structure development 5409
        multicellular organism development 4972
          tube development 990
            tube morphogenesis 804
              tube formation 149
                epithelial tube formation 134
                  embryonic epithelial tube formation 126
                    neural tube formation 107
                      primary neural tube formation 100
                        neural tube closure 93
                          establishment of planar polarity involved in neural tube closure 15
                            regulation of establishment of planar polarity involved in neural tube closure 14
                              planar cell polarity pathway involved in neural tube closure 13
                                negative regulation of planar cell polarity pathway involved in neural tube closure 0
                                regulation of planar cell polarity pathway involved in neural tube closure + 1
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.