ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of kidney development
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Accession:GO:0090185 term browser browse the term
Definition:Any process that decreases the rate, frequency or extent of kidney development. Kidney development is the process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine.
Synonyms:related_synonym: negative regulation of nephrogenesis


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negative regulation of apoptotic process involved in metanephric collecting duct development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pax2 paired box 2 JBrowse link 1 264,493,579 264,585,073 RGD:1624291
RGD:1600115
G Pax8 paired box 8 JBrowse link 3 1,527,316 1,586,019 RGD:1624291
RGD:1600115
negative regulation of apoptotic process involved in metanephric nephron tubule development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pax2 paired box 2 JBrowse link 1 264,493,579 264,585,073 RGD:1624291
RGD:1600115
G Pax8 paired box 8 JBrowse link 3 1,527,316 1,586,019 RGD:1624291
RGD:1600115
negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmp4 bone morphogenetic protein 4 JBrowse link 15 20,776,060 20,791,013 RGD:1600115
RGD:1624291
negative regulation of branching involved in ureteric bud morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmp4 bone morphogenetic protein 4 JBrowse link 15 20,776,060 20,791,013 RGD:1600115
RGD:1624291
G Tacstd2 tumor-associated calcium signal transducer 2 JBrowse link 4 98,341,187 98,342,887 RGD:1600115
RGD:1624291
negative regulation of cell proliferation involved in kidney development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Flcn folliculin JBrowse link 10 46,153,185 46,172,331 RGD:1600115
RGD:1624291
negative regulation of cell proliferation involved in mesonephros development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gata3 GATA binding protein 3 JBrowse link 17 72,419,752 72,452,043 RGD:1624291
RGD:1600115
negative regulation of epithelial cell differentiation involved in kidney development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mmp9 matrix metallopeptidase 9 JBrowse link 3 161,413,410 161,421,473 RGD:1600115
RGD:1624291
negative regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gata3 GATA binding protein 3 JBrowse link 17 72,419,752 72,452,043 RGD:1624291
RGD:1600115
negative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gata3 GATA binding protein 3 JBrowse link 17 72,419,752 72,452,043 RGD:1624291
RGD:1600115
negative regulation of glomerular mesangial cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmp4 bone morphogenetic protein 4 JBrowse link 15 20,776,060 20,791,013 RGD:1600115
RGD:1624291
G Bmp7 bone morphogenetic protein 7 JBrowse link 3 170,879,972 170,955,820 RGD:1624291
RGD:1600115
G Ifng interferon gamma JBrowse link 7 61,337,383 61,341,419 RGD:10755757
negative regulation of glomerulus development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmp4 bone morphogenetic protein 4 JBrowse link 15 20,776,060 20,791,013 RGD:1624291
RGD:1600115
negative regulation of kidney smooth muscle cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Shh sonic hedgehog signaling molecule JBrowse link 4 718,538 727,691 RGD:1600115
RGD:1624291
negative regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hnf1b HNF1 homeobox B JBrowse link 10 71,159,863 71,218,902 RGD:1624291
RGD:1600115
negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pax2 paired box 2 JBrowse link 1 264,493,579 264,585,073 RGD:1624291
RGD:1600115
G Pax8 paired box 8 JBrowse link 3 1,527,316 1,586,019 RGD:1624291
RGD:1600115
negative regulation of mesenchymal cell apoptotic process involved in metanephros development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hnf1b HNF1 homeobox B JBrowse link 10 71,159,863 71,218,902 RGD:1624291
RGD:1600115
G Pax2 paired box 2 JBrowse link 1 264,493,579 264,585,073 RGD:1624291
RGD:1600115
G Pax8 paired box 8 JBrowse link 3 1,527,316 1,586,019 RGD:1624291
RGD:1600115
G Wt1 WT1 transcription factor JBrowse link 3 95,133,221 95,180,574 RGD:1624291
negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmp7 bone morphogenetic protein 7 JBrowse link 3 170,879,972 170,955,820 RGD:1624291
RGD:1600115
negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cited1 Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1 JBrowse link X 72,128,996 72,133,692 RGD:8554075
G Ctnnb1 catenin beta 1 JBrowse link 8 129,601,511 129,628,378 RGD:1624291
RGD:1600115
G Sall1 spalt-like transcription factor 1 JBrowse link 19 23,387,737 23,405,025 RGD:1624291
negative regulation of metanephric comma-shaped body morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmp4 bone morphogenetic protein 4 JBrowse link 15 20,776,060 20,791,013 RGD:1600115
RGD:1624291
negative regulation of metanephric glomerular mesangial cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Wt1 WT1 transcription factor JBrowse link 3 95,133,221 95,180,574 RGD:1624291
RGD:1600115
negative regulation of metanephric mesenchymal cell migration term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adipoq adiponectin, C1Q and collagen domain containing JBrowse link 11 81,330,845 81,344,488 RGD:1624291
RGD:1600115
negative regulation of metanephric S-shaped body morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmp4 bone morphogenetic protein 4 JBrowse link 15 20,776,060 20,791,013 RGD:1600115
RGD:1624291
negative regulation of nephron tubule epithelial cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Osr1 odd-skipped related transcription factor 1 JBrowse link 6 35,314,431 35,321,458 RGD:1624291
RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17926
    developmental process 6339
      negative regulation of developmental process 1079
        negative regulation of kidney development 17
          negative regulation of cell proliferation involved in kidney development + 6
          negative regulation of epithelial cell differentiation involved in kidney development + 5
          negative regulation of glomerulus development + 4
          negative regulation of kidney smooth muscle cell differentiation 1
          negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis + 4
          negative regulation of mesonephros development + 4
          negative regulation of metanephros development + 9
          negative regulation of pronephric nephron tubule development 0
Path 2
Term Annotations click to browse term
  biological_process 17926
    developmental process 6339
      anatomical structure development 5946
        multicellular organism development 5440
          system development 5021
            urogenital system development 408
              renal system development 358
                kidney development 337
                  regulation of kidney development 61
                    negative regulation of kidney development 17
                      negative regulation of cell proliferation involved in kidney development + 6
                      negative regulation of epithelial cell differentiation involved in kidney development + 5
                      negative regulation of glomerulus development + 4
                      negative regulation of kidney smooth muscle cell differentiation 1
                      negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis + 4
                      negative regulation of mesonephros development + 4
                      negative regulation of metanephros development + 9
                      negative regulation of pronephric nephron tubule development 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.