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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of glomerulus development
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Accession:GO:0090192 term browser browse the term
Definition:Any process that modulates the rate, frequency or extent of glomerulus development, the progression of the glomerulus over time from its initial formation until its mature state. The glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney.


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negative regulation of glomerular mesangial cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 ISO (PMID:17244894) UniProtKB PMID:17244894 NCBI chrNW_004955409:9,432,835...9,439,680 JBrowse link
G Bmp7 bone morphogenetic protein 7 ISO (PMID:17244894) UniProtKB PMID:17244894 NCBI chrNW_004955445:2,154,057...2,235,594 JBrowse link
G Ifng interferon gamma ISO RGD PMID:1906384 RGD:10755757 NCBI chrNW_004955458:14,643,333...14,648,020 JBrowse link
negative regulation of glomerulus development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 ISO (PMID:12141440) UniProtKB PMID:12141440 NCBI chrNW_004955409:9,432,835...9,439,680 JBrowse link
negative regulation of metanephric glomerular mesangial cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wt1 WT1 transcription factor ISO (MGI:MGI:1332959|PMID:10077614) UniProtKB PMID:10077614 MGI:MGI:1332959 NCBI chrNW_004955476:10,464,688...10,504,473 JBrowse link
positive regulation of glomerular mesangial cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C3ar1 complement C3a receptor 1 ISO RGD PMID:23713944 RGD:7411623 NCBI chrNW_004955413:6,707,003...6,715,689 JBrowse link
G Cflar CASP8 and FADD like apoptosis regulator ISO RGD PMID:24691542 RGD:11341715 NCBI chrNW_004955403:415,092...442,214 JBrowse link
G Il6r interleukin 6 receptor ISO (PMID:26563755) ARUK-UCL PMID:26563755 NCBI chrNW_004955545:932,814...979,359 JBrowse link
G Itgb3 integrin subunit beta 3 ISO RGD PMID:20135641 RGD:4892623 NCBI chrNW_004955478:9,788,192...9,830,254 JBrowse link
G Pdgfb platelet derived growth factor subunit B ISO (PMID:11788434), (PMID:16014047) UniProtKB PMID:11788434, PMID:16014047 NCBI chrNW_004955413:25,150,702...25,166,987 JBrowse link
G Pdgfd platelet derived growth factor D ISO RGD PMID:12937299 RGD:9854637 NCBI chrNW_004955412:6,868,995...7,093,353 JBrowse link
G Serpinb7 serpin family B member 7 ISO RGD PMID:21945418 RGD:7207383 NCBI chrNW_004955402:47,599,503...47,649,537 JBrowse link
positive regulation of glomerular metanephric mesangial cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Egr1 early growth response 1 ISO PMID:8910451 UniProt PMID:8910451 RGD:8553929 NCBI chrNW_004955418:2,001,509...2,005,269 JBrowse link
positive regulation of glomerulus development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nog noggin ISO (MGI:MGI:2446986|PMID:12141440) UniProtKB PMID:12141440 MGI:MGI:2446986 NCBI chrNW_004955451:6,192,368...6,193,766 JBrowse link
positive regulation of metanephric glomerular visceral epithelial cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adipoq adiponectin, C1Q and collagen domain containing ISO (MGI:MGI:3795840|PMID:18431508) UniProtKB PMID:18431508 MGI:MGI:3795840 NCBI chrNW_004955420:20,911,181...20,922,992 JBrowse link
positive regulation of metanephric glomerulus development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agtr2 angiotensin II receptor type 2 ISO (MGI:MGI:3808848|PMID:18607644) UniProtKB PMID:18607644 MGI:MGI:3808848 NCBI chrNW_004955534:3,653,112...3,654,248 JBrowse link
G Pax2 paired box 2 ISO (MGI:MGI:3697544|PMID:17047028) UniProtKB PMID:17047028 MGI:MGI:3697544 NCBI chrNW_004955485:9,351,913...9,430,607 JBrowse link
G Ret ret proto-oncogene ISO (MGI:MGI:3697544|PMID:17047028) UniProtKB PMID:17047028 MGI:MGI:3697544 NCBI chrNW_004955546:1,221,995...1,252,147 JBrowse link
regulation of glomerular mesangial cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pdgfa platelet derived growth factor subunit A NOT ISO (PMID:11788434) UniProtKB PMID:11788434 NCBI chrNW_004955460:8,328,400...8,346,755 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 11860
    developmental process 5598
      anatomical structure development 5237
        glomerulus development 68
          regulation of glomerulus development 18
            negative regulation of glomerulus development + 4
            positive regulation of glomerulus development + 13
            regulation of glomerular mesangial cell proliferation + 13
            regulation of mesonephric glomerulus development + 0
            regulation of metanephric glomerulus development + 6
Path 2
Term Annotations click to browse term
  biological_process 11860
    developmental process 5598
      anatomical structure development 5237
        multicellular organism development 4801
          system development 4520
            urogenital system development 401
              renal system development 354
                kidney development 340
                  nephron development 158
                    glomerulus development 68
                      regulation of glomerulus development 18
                        negative regulation of glomerulus development + 4
                        positive regulation of glomerulus development + 13
                        regulation of glomerular mesangial cell proliferation + 13
                        regulation of mesonephric glomerulus development + 0
                        regulation of metanephric glomerulus development + 6
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.