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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of glomerulus development
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Accession:GO:0090192 term browser browse the term
Definition:Any process that modulates the rate, frequency or extent of glomerulus development, the progression of the glomerulus over time from its initial formation until its mature state. The glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney.


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negative regulation of glomerular mesangial cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 ISO MGI GO_REF:0000096, MGI:MGI:4834177 NCBI chr14:46,383,525...46,390,669
Ensembl chr14:46,383,520...46,390,669
JBrowse link
G Bmp7 bone morphogenetic protein 7 ISO MGI GO_REF:0000096, MGI:MGI:4834177 NCBI chr 2:172,868,012...172,940,321
Ensembl chr 2:172,868,012...172,940,321
JBrowse link
G Ifng interferon gamma ISO RGD GO_REF:0000096, MGI:MGI:4417868 NCBI chr10:118,441,046...118,445,894
Ensembl chr10:118,441,046...118,445,892
JBrowse link
negative regulation of glomerulus development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 ISO MGI GO_REF:0000096, MGI:MGI:4834177 NCBI chr14:46,383,525...46,390,669
Ensembl chr14:46,383,520...46,390,669
JBrowse link
negative regulation of metanephric glomerular mesangial cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wt1 Wilms tumor 1 homolog IMP (MGI:MGI:1332959|PMID:10077614) UniProtKB PMID:10077614 MGI:MGI:1332959 NCBI chr 2:105,126,529...105,173,614
Ensembl chr 2:105,126,529...105,173,616
JBrowse link
positive regulation of glomerular mesangial cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C3ar1 complement component 3a receptor 1 ISO RGD GO_REF:0000096, MGI:MGI:4417868 NCBI chr 6:122,847,140...122,856,157
Ensembl chr 6:122,847,138...122,856,161
JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator ISO RGD GO_REF:0000096, MGI:MGI:4417868 NCBI chr 1:58,711,311...58,758,884
Ensembl chr 1:58,711,508...58,758,884
JBrowse link
G Il6ra interleukin 6 receptor, alpha ISO MGI GO_REF:0000096, MGI:MGI:4834177 NCBI chr 3:89,869,324...89,913,196
Ensembl chr 3:89,864,059...89,913,196
JBrowse link
G Itgb3 integrin beta 3 ISO RGD GO_REF:0000096, MGI:MGI:4417868 NCBI chr11:104,608,000...104,670,476
Ensembl chr11:104,608,000...104,670,476
JBrowse link
G Pdgfb platelet derived growth factor, B polypeptide ISO MGI GO_REF:0000096, MGI:MGI:4834177 NCBI chr15:79,995,865...80,024,614
Ensembl chr15:79,995,874...80,014,977
JBrowse link
G Pdgfd platelet-derived growth factor, D polypeptide ISO RGD GO_REF:0000096, MGI:MGI:4417868 NCBI chr 9:6,168,363...6,534,284
Ensembl chr 9:6,168,584...6,378,850
JBrowse link
G Serpinb7 serine (or cysteine) peptidase inhibitor, clade B, member 7 ISO RGD GO_REF:0000096, MGI:MGI:4417868 NCBI chr 1:107,422,689...107,452,689
Ensembl chr 1:107,399,655...107,452,689
JBrowse link
positive regulation of glomerular metanephric mesangial cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Egr1 early growth response 1 ISO RGD GO_REF:0000096, MGI:MGI:4417868 NCBI chr18:34,861,207...34,864,956
Ensembl chr18:34,859,823...34,864,984
JBrowse link
positive regulation of glomerulus development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nog noggin IDA (MGI:MGI:2446986|PMID:12141440) UniProtKB PMID:12141440 MGI:MGI:2446986 NCBI chr11:89,300,638...89,302,559
Ensembl chr11:89,300,638...89,302,332
JBrowse link
positive regulation of metanephric glomerular visceral epithelial cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adipoq adiponectin, C1Q and collagen domain containing IMP (MGI:MGI:3795840|PMID:18431508) UniProtKB PMID:18431508 MGI:MGI:3795840 NCBI chr16:23,146,536...23,157,968
Ensembl chr16:23,146,536...23,158,028
JBrowse link
positive regulation of metanephric glomerulus development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agtr2 angiotensin II receptor, type 2 IMP (MGI:MGI:3808848|PMID:18607644) UniProtKB PMID:18607644 MGI:MGI:3808848 NCBI chr  X:21,484,624...21,488,833
Ensembl chr  X:21,484,544...21,489,164
JBrowse link
G Pax2 paired box 2 IMP (MGI:MGI:3697544|PMID:17047028) UniProtKB PMID:17047028 MGI:MGI:3697544 NCBI chr19:44,746,601...44,838,269
Ensembl chr19:44,756,045...44,837,871
JBrowse link
G Ret ret proto-oncogene IMP (MGI:MGI:3697544|PMID:17047028) UniProtKB PMID:17047028 MGI:MGI:3697544 NCBI chr 6:118,151,748...118,197,744
Ensembl chr 6:118,151,745...118,197,718
JBrowse link
regulation of glomerular mesangial cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pdgfa platelet derived growth factor, alpha NOT ISO (PMID:11788434) UniProtKB PMID:11788434 NCBI chr 5:138,976,014...139,000,792
Ensembl chr 5:138,976,014...138,997,370
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 23369
    developmental process 7016
      anatomical structure development 6488
        glomerulus development 72
          regulation of glomerulus development 18
            negative regulation of glomerulus development + 4
            positive regulation of glomerulus development + 13
            regulation of glomerular mesangial cell proliferation + 13
            regulation of mesonephric glomerulus development + 0
            regulation of metanephric glomerulus development + 6
Path 2
Term Annotations click to browse term
  biological_process 23369
    developmental process 7016
      anatomical structure development 6488
        multicellular organism development 5954
          system development 5368
            urogenital system development 436
              renal system development 387
                kidney development 373
                  nephron development 165
                    glomerulus development 72
                      regulation of glomerulus development 18
                        negative regulation of glomerulus development + 4
                        positive regulation of glomerulus development + 13
                        regulation of glomerular mesangial cell proliferation + 13
                        regulation of mesonephric glomerulus development + 0
                        regulation of metanephric glomerulus development + 6
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.