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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of glomerulus development
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Accession:GO:0090192 term browser browse the term
Definition:Any process that modulates the rate, frequency or extent of glomerulus development, the progression of the glomerulus over time from its initial formation until its mature state. The glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney.


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negative regulation of glomerular mesangial cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP4 bone morphogenetic protein 4 IEA Ensembl GO_REF:0000107 NCBI chr 1:183,415,989...183,422,888
Ensembl chr 1:183,416,134...183,792,417
JBrowse link
G BMP7 bone morphogenetic protein 7 IEA Ensembl GO_REF:0000107 NCBI chr17:57,567,770...57,676,516
Ensembl chr17:57,584,091...57,676,944
JBrowse link
G IFNG interferon gamma ISO RGD PMID:1906384 RGD:10755757 NCBI chr 5:32,477,906...32,482,670
Ensembl chr 5:32,477,848...32,482,752
JBrowse link
negative regulation of glomerulus development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP4 bone morphogenetic protein 4 ISO (PMID:12141440) UniProtKB PMID:12141440 NCBI chr 1:183,415,989...183,422,888
Ensembl chr 1:183,416,134...183,792,417
JBrowse link
negative regulation of metanephric glomerular mesangial cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G WT1 WT1 transcription factor ISS UniProt GO_REF:0000024 NCBI chr 2:28,411,467...28,456,007
Ensembl chr 2:28,411,794...28,456,003
JBrowse link
positive regulation of glomerular mesangial cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C3AR1 complement C3a receptor 1 ISO RGD PMID:23713944 RGD:7411623 NCBI chr 5:63,088,778...63,098,750 JBrowse link
G CFLAR CASP8 and FADD like apoptosis regulator ISO RGD PMID:24691542 RGD:11341715 NCBI chr15:104,780,744...104,835,631
Ensembl chr15:104,781,615...104,844,921
JBrowse link
G IL6R interleukin 6 receptor IEA Ensembl GO_REF:0000107 NCBI chr 4:95,322,426...95,381,393
Ensembl chr 4:95,322,426...95,381,282
JBrowse link
G ITGB3 integrin subunit beta 3 ISO RGD PMID:20135641 RGD:4892623 NCBI chr12:16,694,466...16,752,228
Ensembl chr12:16,693,505...16,752,292
JBrowse link
G PDGFB platelet derived growth factor subunit B IEA Ensembl GO_REF:0000107 Ensembl chr 5:8,986,461...9,007,446 JBrowse link
G PDGFD platelet derived growth factor D ISO RGD PMID:12937299 RGD:9854637 NCBI chr 9:34,388,636...34,621,227
Ensembl chr 9:34,388,636...34,621,244
JBrowse link
G SERPINB7 serpin family B member 7 ISO RGD PMID:21945418 RGD:7207383 NCBI chr 1:157,953,872...157,999,242
Ensembl chr 1:157,953,870...157,998,842
JBrowse link
positive regulation of glomerular metanephric mesangial cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EGR1 early growth response 1 ISO PMID:8910451 UniProt PMID:8910451 RGD:8553929 NCBI chr 2:140,440,829...140,445,302
Ensembl chr 2:140,441,421...140,445,296
JBrowse link
positive regulation of glomerulus development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NOG noggin ISS UniProt GO_REF:0000024 NCBI chr12:32,891,321...32,892,206
Ensembl chr12:32,891,321...32,892,206
JBrowse link
positive regulation of metanephric glomerular visceral epithelial cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADIPOQ adiponectin, C1Q and collagen domain containing IEA
ISS
Ensembl
UniProt
GO_REF:0000024, GO_REF:0000107 NCBI chr13:124,633,906...124,646,237
Ensembl chr13:124,633,684...124,646,648
JBrowse link
positive regulation of metanephric glomerulus development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGTR2 angiotensin II receptor type 2 IEA Ensembl GO_REF:0000107 NCBI chr  X:95,267,709...95,272,237
Ensembl chr  X:95,269,300...95,270,388
JBrowse link
G PAX2 paired box 2 ISO (MGI:MGI:3697544|PMID:17047028) UniProtKB PMID:17047028 MGI:MGI:3697544 NCBI chr14:111,822,334...111,914,950
Ensembl chr14:111,834,168...111,914,304
JBrowse link
G RET ret proto-oncogene IEA Ensembl GO_REF:0000107 NCBI chr14:61,305,818...61,361,416
Ensembl chr14:61,305,841...61,361,415
JBrowse link
regulation of glomerular mesangial cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PDGFA platelet derived growth factor subunit A NOT ISO (PMID:11788434) UniProtKB PMID:11788434 NCBI chr 3:296,399...322,967
Ensembl chr 3:303,311...323,036
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16524
    developmental process 6285
      anatomical structure development 5826
        glomerulus development 73
          regulation of glomerulus development 18
            negative regulation of glomerulus development + 4
            positive regulation of glomerulus development + 13
            regulation of glomerular mesangial cell proliferation + 13
            regulation of mesonephric glomerulus development + 0
            regulation of metanephric glomerulus development + 6
Path 2
Term Annotations click to browse term
  biological_process 16524
    developmental process 6285
      anatomical structure development 5826
        multicellular organism development 5330
          system development 4955
            urogenital system development 423
              renal system development 373
                kidney development 360
                  nephron development 165
                    glomerulus development 73
                      regulation of glomerulus development 18
                        negative regulation of glomerulus development + 4
                        positive regulation of glomerulus development + 13
                        regulation of glomerular mesangial cell proliferation + 13
                        regulation of mesonephric glomerulus development + 0
                        regulation of metanephric glomerulus development + 6
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.