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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of glomerulus development
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Accession:GO:0090192 term browser browse the term
Definition:Any process that modulates the rate, frequency or extent of glomerulus development, the progression of the glomerulus over time from its initial formation until its mature state. The glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney.


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negative regulation of glomerular mesangial cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:17244894)
Ensembl
UniProt
RGD
PMID:17244894 GO_REF:0000024, GO_REF:0000107 NCBI chr15:20,776,060...20,791,013
Ensembl chr15:20,776,054...20,822,740
JBrowse link
G Bmp7 bone morphogenetic protein 7 ISO (PMID:17244894) RGD PMID:17244894 NCBI chr 3:170,879,972...170,955,820
Ensembl chr 3:170,879,973...170,955,399
JBrowse link
G Ifng interferon gamma IMP RGD PMID:1906384 RGD:10755757 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
negative regulation of glomerulus development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 ISO
ISS
(PMID:12141440)
GO_REF:0000024
RGD
UniProt
PMID:12141440 GO_REF:0000024 NCBI chr15:20,776,060...20,791,013
Ensembl chr15:20,776,054...20,822,740
JBrowse link
negative regulation of metanephric glomerular mesangial cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wt1 WT1 transcription factor ISO
ISS
(MGI:MGI:1332959|PMID:10077614)
GO_REF:0000024
RGD
UniProt
PMID:10077614 GO_REF:0000024, MGI:MGI:1332959 NCBI chr 3:95,133,221...95,180,574
Ensembl chr 3:95,133,713...95,180,564
JBrowse link
positive regulation of glomerular mesangial cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C3ar1 complement C3a receptor 1 IMP RGD PMID:23713944 RGD:7411623 NCBI chr 4:155,681,767...155,691,240
Ensembl chr 4:155,684,029...155,690,869
JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator IMP RGD PMID:24691542 RGD:11341715 NCBI chr 9:65,534,608...65,586,395
Ensembl chr 9:65,534,704...65,587,251
JBrowse link
G Il6r interleukin 6 receptor ISO (PMID:26563755) RGD PMID:26563755 NCBI chr 2:189,196,180...189,255,987
Ensembl chr 2:189,205,701...189,254,628
JBrowse link
G Itgb3 integrin subunit beta 3 IMP RGD PMID:20135641 RGD:4892623 NCBI chr10:92,667,869...92,783,413
Ensembl chr10:92,667,869...92,783,410
JBrowse link
G Pdgfb platelet derived growth factor subunit B IEA
ISO
ISS
GO_REF:0000107
(PMID:11788434), (PMID:16014047)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:11788434, PMID:16014047 GO_REF:0000024, GO_REF:0000107 NCBI chr 7:121,215,458...121,233,092
Ensembl chr 7:121,214,628...121,232,741
JBrowse link
G Pdgfd platelet derived growth factor D IMP RGD PMID:12937299 RGD:9854637 NCBI chr 8:4,441,010...4,666,754
Ensembl chr 8:4,440,876...4,669,014
JBrowse link
G Serpinb7 serpin family B member 7 IMP RGD PMID:21945418 RGD:7207383 NCBI chr13:27,282,456...27,354,775
Ensembl chr13:27,312,498...27,354,052
JBrowse link
positive regulation of glomerular metanephric mesangial cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Egr1 early growth response 1 IMP PMID:8910451 UniProt PMID:8910451 RGD:8553929 NCBI chr18:27,657,903...27,660,101
Ensembl chr18:27,657,628...27,661,429
JBrowse link
positive regulation of glomerulus development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nog noggin IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(MGI:MGI:2446986|PMID:12141440)
Ensembl
UniProt
RGD
PMID:12141440 GO_REF:0000024, GO_REF:0000107, MGI:MGI:2446986 NCBI chr10:76,811,759...76,813,386
Ensembl chr10:76,811,759...76,813,386
JBrowse link
positive regulation of metanephric glomerular visceral epithelial cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adipoq adiponectin, C1Q and collagen domain containing ISO
ISS
(MGI:MGI:3795840|PMID:18431508)
GO_REF:0000024
RGD
UniProt
PMID:18431508 GO_REF:0000024, MGI:MGI:3795840 NCBI chr11:81,330,845...81,344,488
Ensembl chr11:81,330,293...81,344,488
JBrowse link
positive regulation of metanephric glomerulus development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agtr2 angiotensin II receptor, type 2 ISO (MGI:MGI:3808848|PMID:18607644) RGD PMID:18607644 MGI:MGI:3808848 NCBI chr  X:119,389,480...119,393,845
Ensembl chr  X:119,390,013...119,393,842
JBrowse link
G Pax2 paired box 2 ISO
ISS
(MGI:MGI:3697544|PMID:17047028)
GO_REF:0000024
RGD
UniProt
PMID:17047028 GO_REF:0000024, MGI:MGI:3697544 NCBI chr 1:264,493,579...264,585,073
Ensembl chr 1:264,504,591...264,583,329
JBrowse link
G Ret ret proto-oncogene ISO (MGI:MGI:3697544|PMID:17047028) RGD PMID:17047028 MGI:MGI:3697544 NCBI chr 4:150,202,170...150,249,196
Ensembl chr 4:150,202,058...150,244,372
JBrowse link
regulation of glomerular mesangial cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pdgfa platelet derived growth factor subunit A NOT ISO
ISS
(PMID:11788434)
GO_REF:0000024
RGD
UniProt
PMID:11788434 GO_REF:0000024 NCBI chr12:17,734,141...17,756,186
Ensembl chr12:17,734,133...17,755,285
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20017
    developmental process 6813
      anatomical structure development 6256
        glomerulus development 73
          regulation of glomerulus development 18
            negative regulation of glomerulus development + 4
            positive regulation of glomerulus development + 13
            regulation of glomerular mesangial cell proliferation + 13
            regulation of mesonephric glomerulus development + 0
            regulation of metanephric glomerulus development + 6
Path 2
Term Annotations click to browse term
  biological_process 20017
    developmental process 6813
      anatomical structure development 6256
        multicellular organism development 5735
          system development 5272
            urogenital system development 433
              renal system development 383
                kidney development 369
                  nephron development 166
                    glomerulus development 73
                      regulation of glomerulus development 18
                        negative regulation of glomerulus development + 4
                        positive regulation of glomerulus development + 13
                        regulation of glomerular mesangial cell proliferation + 13
                        regulation of mesonephric glomerulus development + 0
                        regulation of metanephric glomerulus development + 6
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.