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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of spindle checkpoint
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Accession:GO:0090232 term browser browse the term
Definition:Any process that increases the rate, frequency, or extent of the spindle checkpoint, a cell cycle checkpoint that delays the metaphase/anaphase transition until the spindle is correctly assembled and oriented, and chromosomes are attached to the spindle.
Synonyms:narrow_synonym: spindle checkpoint activation


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positive regulation of mitotic cell cycle spindle assembly checkpoint term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dync1li1 dynein cytoplasmic 1 light intermediate chain 1 IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:19229290)
Ensembl
UniProt
RGD
PMID:19229290 GO_REF:0000024, GO_REF:0000107 NCBI chr 8:122,743,274...122,776,801
Ensembl chr 8:122,743,189...122,776,806
JBrowse link
G Gen1 GEN1 Holliday junction 5' flap endonuclease ISO (PMID:23108668) RGD PMID:23108668 NCBI chr 6:36,910,064...36,940,868
Ensembl chr 6:36,910,675...36,940,868
JBrowse link
G Mad2l1 mitotic arrest deficient 2 like 1 ISO (PMID:20870947)
(MGI:MGI:4839685|PMID:20870947)
RGD PMID:20870947 MGI:MGI:4839685 NCBI chr 4:97,530,993...97,543,179
Ensembl chr 4:97,531,083...97,537,086
JBrowse link
G Ndc80 NDC80 kinetochore complex component ISO (PMID:25743205) RGD PMID:25743205 NCBI chr 9:119,837,857...119,871,435
Ensembl chr 9:119,839,016...119,871,382
JBrowse link
G Pcid2 PCI domain containing 2 ISO (PMID:20870947)
(MGI:MGI:4839685|PMID:20870947)
RGD PMID:20870947 MGI:MGI:4839685 NCBI chr16:81,757,582...81,783,047
Ensembl chr16:81,756,971...81,783,047
JBrowse link
G Tpr translocated promoter region, nuclear basket protein ISS
ISO
GO_REF:0000024
(PMID:18981471), (PMID:19273613)
UniProt
RGD
PMID:18981471, PMID:19273613 GO_REF:0000024 NCBI chr13:67,611,685...67,672,833
Ensembl chr13:67,611,708...67,672,827
JBrowse link
G Xrcc3 X-ray repair cross complementing 3 ISO (PMID:23108668) RGD PMID:23108668 NCBI chr 6:136,366,917...136,380,751
Ensembl chr 6:136,371,555...136,379,348
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20028
    cellular process 18800
      cell cycle checkpoint 165
        spindle checkpoint 34
          positive regulation of spindle checkpoint 7
            positive regulation of meiosis I spindle assembly checkpoint + 0
            positive regulation of mitotic cell cycle spindle assembly checkpoint + 7
Path 2
Term Annotations click to browse term
  biological_process 20028
    biological regulation 13773
      regulation of biological process 13075
        negative regulation of biological process 5686
          negative regulation of cellular process 5156
            negative regulation of cell cycle 443
              cell cycle checkpoint 165
                spindle checkpoint 34
                  regulation of spindle checkpoint 14
                    positive regulation of spindle checkpoint 7
                      positive regulation of meiosis I spindle assembly checkpoint + 0
                      positive regulation of mitotic cell cycle spindle assembly checkpoint + 7
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.