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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of mitotic cell cycle spindle assembly checkpoint
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Accession:GO:0090266 term browser browse the term
Definition:Any process that modulates the rate, frequency, or extent of the mitotic cell cycle spindle assembly checkpoint, a cell cycle checkpoint that delays the metaphase/anaphase transition of a mitotic nuclear division until the spindle is correctly assembled and chromosomes are attached to the spindle.


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regulation of mitotic cell cycle spindle assembly checkpoint term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANAPC15 anaphase promoting complex subunit 15 ISO (PMID:21926987) UniProtKB PMID:21926987 NCBI chr11:67,186,653...67,193,102
Ensembl chr11:70,411,031...70,416,484
JBrowse link
G CCNB1 cyclin B1 ISO (PMID:18195732) BHF-UCL PMID:18195732 NCBI chr 5:44,826,103...44,836,832
Ensembl chr 5:46,394,362...46,405,332
JBrowse link
G CDK5RAP2 CDK5 regulatory subunit associated protein 2 ISO (PMID:19282672) UniProtKB PMID:19282672 NCBI chr 9:91,519,179...91,707,469
Ensembl chr 9:119,868,015...120,055,608
JBrowse link
G LCMT1 leucine carboxyl methyltransferase 1 ISO (PMID:17724024) MGI PMID:17724024 Ensembl chr16:25,351,814...25,418,285 JBrowse link
G USP44 ubiquitin specific peptidase 44 ISO (MGI:5448515|PMID:21853124) UniProt PMID:21853124 MGI:5448515 NCBI chr12:93,111,293...93,146,889
Ensembl chr12:96,503,794...96,536,094
JBrowse link
deactivation of mitotic spindle assembly checkpoint term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDT1 chromatin licensing and DNA replication factor 1 ISO (PMID:22581055) CAFA PMID:22581055 NCBI chr16:69,516,728...69,522,419
Ensembl chr16:89,174,071...89,177,823
JBrowse link
positive regulation of mitotic cell cycle spindle assembly checkpoint term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DYNC1LI1 dynein cytoplasmic 1 light intermediate chain 1 ISO (PMID:19229290) UniProtKB PMID:19229290 NCBI chr 3:32,450,693...32,495,400
Ensembl chr 3:32,758,407...32,804,117
JBrowse link
G GEN1 GEN1 Holliday junction 5' flap endonuclease ISO (PMID:23108668) UniProtKB PMID:23108668 NCBI chr2A:17,735,953...17,766,018
Ensembl chr2A:17,862,070...17,892,048
JBrowse link
G MAD2L1 mitotic arrest deficient 2 like 1 ISO (PMID:20870947)
(MGI:4839685|PMID:20870947)
UniProtKB
UniProt
PMID:20870947 MGI:4839685 NCBI chr 4:112,247,808...112,255,202
Ensembl chr 4:123,397,355...123,405,535
JBrowse link
G NDC80 NDC80 kinetochore complex component ISO (PMID:25743205) UniProtKB PMID:25743205 NCBI chr18:11,666,099...11,711,456
Ensembl chr18:13,972,637...14,018,261
JBrowse link
G PCID2 PCI domain containing 2 ISO (PMID:20870947)
(MGI:4839685|PMID:20870947)
UniProtKB
UniProt
PMID:20870947 MGI:4839685 NCBI chr13:94,319,699...94,350,763
Ensembl chr13:113,388,251...113,419,251
JBrowse link
G TPR translocated promoter region, nuclear basket protein ISO (PMID:18981471), (PMID:19273613) UniProt PMID:18981471, PMID:19273613 NCBI chr 1:161,842,037...161,903,567
Ensembl chr 1:165,993,726...166,055,223
JBrowse link
G XRCC3 X-ray repair cross complementing 3 ISO (PMID:23108668) UniProtKB PMID:23108668 NCBI chr14:84,323,644...84,341,763
Ensembl chr14:104,131,903...104,149,037
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12566
    cellular process 11671
      cell cycle process 1004
        regulation of cell cycle process 566
          regulation of mitotic nuclear division 85
            regulation of mitotic cell cycle spindle assembly checkpoint 13
              deactivation of mitotic spindle assembly checkpoint 1
              positive regulation of mitotic cell cycle spindle assembly checkpoint + 7
Path 2
Term Annotations click to browse term
  biological_process 12566
    cellular process 11671
      cellular component organization or biogenesis 5015
        cellular component organization 4935
          organelle organization 3054
            organelle fission 419
              nuclear division 374
                mitotic nuclear division 234
                  mitotic sister chromatid segregation 125
                    mitotic sister chromatid separation 43
                      regulation of mitotic sister chromatid separation 40
                        metaphase/anaphase transition of mitotic cell cycle 40
                          regulation of mitotic metaphase/anaphase transition 36
                            negative regulation of mitotic metaphase/anaphase transition 28
                              mitotic spindle assembly checkpoint 26
                                regulation of mitotic cell cycle spindle assembly checkpoint 13
                                  deactivation of mitotic spindle assembly checkpoint 1
                                  positive regulation of mitotic cell cycle spindle assembly checkpoint + 7
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.