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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of mitotic cell cycle spindle assembly checkpoint
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Accession:GO:0090267 term browser browse the term
Definition:Any process that increases the rate, frequency, or extent of the mitotic cell cycle spindle assembly checkpoint, a cell cycle checkpoint that delays the metaphase/anaphase transition of a mitotic nuclear division until the spindle is correctly assembled and chromosomes are attached to the spindle.


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positive regulation of mitotic cell cycle spindle assembly checkpoint term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DYNC1LI1 dynein cytoplasmic 1 light intermediate chain 1 IEA Ensembl GO_REF:0000107 NCBI chr23:12,235,539...12,283,851
Ensembl chr23:12,235,104...12,277,031
JBrowse link
G GEN1 GEN1 Holliday junction 5' flap endonuclease IEA Ensembl GO_REF:0000107 NCBI chr17:13,201,540...13,233,028
Ensembl chr17:13,201,777...13,232,120
JBrowse link
G MAD2L1 mitotic arrest deficient 2 like 1 ISO (PMID:20870947)
(MGI:4839685|PMID:20870947)
UniProtKB
UniProt
PMID:20870947 MGI:4839685 NCBI chr18:55,653,677...55,661,017 JBrowse link
G NDC80 NDC80 kinetochore complex component IEA Ensembl GO_REF:0000107 NCBI chr 7:69,268,218...69,317,126
Ensembl chr 7:69,268,242...69,317,072
JBrowse link
G PCID2 PCI domain containing 2 IEA Ensembl GO_REF:0000107 NCBI chr22:60,602,440...60,623,811
Ensembl chr22:60,602,888...60,623,719
JBrowse link
G TPR translocated promoter region, nuclear basket protein IEA Ensembl GO_REF:0000107 NCBI chr 7:19,376,951...19,442,368
Ensembl chr 7:19,376,975...19,442,303
JBrowse link
G XRCC3 X-ray repair cross complementing 3 IEA Ensembl GO_REF:0000107 NCBI chr 8:71,441,732...71,452,922
Ensembl chr 8:71,442,429...71,449,408
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16190
    cellular process 15467
      cell cycle process 1161
        positive regulation of cell cycle process 273
          positive regulation of mitotic cell cycle spindle assembly checkpoint 7
            activation of mitotic cell cycle spindle assembly checkpoint 0
Path 2
Term Annotations click to browse term
  biological_process 16190
    cellular process 15467
      cellular component organization or biogenesis 6052
        cellular component organization 5884
          organelle organization 3731
            organelle fission 487
              nuclear division 432
                mitotic nuclear division 280
                  mitotic sister chromatid segregation 160
                    mitotic sister chromatid separation 60
                      regulation of mitotic sister chromatid separation 57
                        metaphase/anaphase transition of mitotic cell cycle 56
                          regulation of mitotic metaphase/anaphase transition 53
                            negative regulation of mitotic metaphase/anaphase transition 37
                              mitotic spindle assembly checkpoint 35
                                regulation of mitotic cell cycle spindle assembly checkpoint 13
                                  positive regulation of mitotic cell cycle spindle assembly checkpoint 7
                                    activation of mitotic cell cycle spindle assembly checkpoint 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.