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ONTOLOGY REPORT - ANNOTATIONS


Term:mitotic spindle assembly
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Accession:GO:0090307 term browser browse the term
Definition:Mitotic bipolar spindle assembly begins with spindle microtubule nucleation from the separated spindle pole body, includes spindle elongation during prometaphase, and is complete when all kinetochores are stably attached the spindle, and the spindle assembly checkpoint is satisfied.
Synonyms:exact_synonym: spindle assembly involved in mitosis


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mitotic spindle assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aaas aladin WD repeat nucleoporin ISO (PMID:26246606) RGD PMID:26246606 NCBI chr 7:143,937,198...143,956,668
Ensembl chr 7:143,937,199...143,956,668
JBrowse link
G Abraxas1 abraxas 1, BRCA1 A complex subunit IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr14:10,424,674...10,439,010
Ensembl chr14:10,424,674...10,439,003
JBrowse link
G Abraxas2 abraxas 2, BRISC complex subunit ISO
IBA
(PMID:26195665)
PMID:21873635
RGD PMID:26195665, PMID:21873635 RGD:13792537 NCBI chr 1:204,861,768...204,887,344
Ensembl chr 1:204,861,566...204,887,377
JBrowse link
G Arhgef10 Rho guanine nucleotide exchange factor 10 ISO
IBA
(PMID:19635168)
PMID:21873635
RGD PMID:19635168, PMID:21873635 RGD:13792537 NCBI chr16:79,725,629...79,817,065
Ensembl chr16:79,725,643...79,793,619
JBrowse link
G Bccip BRCA2 and CDKN1A interacting protein ISO
IBA
(PMID:28394342)
PMID:21873635
RGD PMID:28394342, PMID:21873635 RGD:13792537 NCBI chr 1:205,777,474...205,789,887
Ensembl chr 1:205,777,130...205,790,175
JBrowse link
G Cdc20 cell division cycle 20 ISO (MGI:MGI:3710433|PMID:17325031) RGD PMID:17325031 MGI:MGI:3710433 NCBI chr 5:137,260,728...137,264,931
Ensembl chr 5:137,260,739...137,265,015
JBrowse link
G Cep192 centrosomal protein 192 ISO (PMID:17980596) RGD PMID:17980596 NCBI chr18:63,572,084...63,656,302
Ensembl chr18:63,524,452...63,656,286
JBrowse link
G Chek2 checkpoint kinase 2 ISO (PMID:20364141) RGD PMID:20364141 NCBI chr12:51,845,574...51,878,098
Ensembl chr12:51,845,796...51,877,624
JBrowse link
G Clasp1 cytoplasmic linker associated protein 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr13:34,365,038...34,584,651
Ensembl chr13:34,365,147...34,584,651
JBrowse link
G Clasp2 cytoplasmic linker associated protein 2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:122,003,719...122,185,495
Ensembl chr 8:122,003,916...122,185,495
JBrowse link
G Flna filamin A ISO (PMID:18548008) RGD PMID:18548008 NCBI chr  X:156,460,785...156,487,245
Ensembl chr  X:156,463,953...156,487,245
JBrowse link
G Golga2 golgin A2 IMP
ISS
ISO
PMID:26165940
GO_REF:0000024
(PMID:26165940)
UniProt
RGD
PMID:26165940, PMID:26165940 GO_REF:0000024, RGD:10400867 NCBI chr 3:11,317,328...11,337,569
Ensembl chr 3:11,317,183...11,336,458
JBrowse link
G Khdc3 KH domain containing 3, subcortical maternal complex member ISO MGI:MGI:3844604 (MGI:MGI:3844372|PMID:19376971) RGD PMID:19376971 MGI:MGI:3844372 NCBI chr 8:79,781,941...79,783,845
Ensembl chr 8:79,781,983...79,783,592
JBrowse link
G Kif11 kinesin family member 11 ISO
IBA
(PMID:15843429), (PMID:19001501)
PMID:21873635
RGD PMID:15843429, PMID:19001501, PMID:21873635 RGD:13792537 NCBI chr 1:256,035,866...256,088,299
Ensembl chr 1:256,035,866...256,088,299
JBrowse link
G Kif2a kinesin family member 2A IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:15843429)
Ensembl
UniProt
RGD
PMID:15843429 GO_REF:0000024, GO_REF:0000107 NCBI chr 2:38,145,507...38,208,765
Ensembl chr 2:38,147,601...38,208,719
JBrowse link
G Kif3b kinesin family member 3B ISO (PMID:19635168) RGD PMID:19635168 NCBI chr 3:148,772,937...148,813,342
Ensembl chr 3:148,773,259...148,813,293
JBrowse link
G Kifc1 kinesin family member C1 ISO
IBA
ISS
(PMID:15843429)
PMID:21873635
GO_REF:0000024
RGD
UniProt
PMID:15843429, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr20:5,509,059...5,526,175
Ensembl chr20:5,509,059...5,526,175
JBrowse link
G Kifc2 kinesin family member C2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:117,722,732...117,730,702
Ensembl chr 7:117,723,263...117,730,702
JBrowse link
G Kpnb1 karyopherin subunit beta 1 IEA
ISO
GO_REF:0000107
(PMID:23783028)
Ensembl
RGD
PMID:23783028 GO_REF:0000107 NCBI chr10:85,096,517...85,124,641
Ensembl chr10:85,093,841...85,124,644
JBrowse link
G Lsm14a LSM14A mRNA processing body assembly factor ISO (PMID:26339800) RGD PMID:26339800 NCBI chr 1:90,200,866...90,246,292
Ensembl chr 1:90,200,876...90,246,297
JBrowse link
G Map9 microtubule-associated protein 9 ISO
IBA
(MGI:MGI:3817836|PMID:18782428)
PMID:21873635
(PMID:16049101)
RGD PMID:16049101, PMID:18782428, PMID:21873635 MGI:MGI:3817836, RGD:13792537 NCBI chr 2:181,331,426...181,367,245
Ensembl chr 2:181,331,464...181,367,244
JBrowse link
G Misp mitotic spindle positioning ISO (PMID:23574715) RGD PMID:23574715 NCBI chr 7:12,691,834...12,707,927
Ensembl chr 7:12,697,743...12,707,922
JBrowse link
G Msto1 misato mitochondrial distribution and morphology regulator 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:188,212,211...188,216,482
Ensembl chr 2:188,212,211...188,216,482
JBrowse link
G Mybl2 MYB proto-oncogene like 2 ISO (MGI:MGI:3801372|PMID:18548008) RGD PMID:18548008 MGI:MGI:3801372 NCBI chr 3:159,421,638...159,450,087
Ensembl chr 3:159,421,671...159,450,086
JBrowse link
G Mzt1 mitotic spindle organizing protein 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr15:83,429,437...83,442,118
Ensembl chr15:83,431,178...83,442,008
JBrowse link
G Nek2 NIMA-related kinase 2 ISO (MGI:MGI:3848119|PMID:19117032) RGD PMID:19117032 MGI:MGI:3848119 NCBI chr13:110,511,546...110,524,750
Ensembl chr13:110,511,668...110,522,769
JBrowse link
G Ofd1 OFD1, centriole and centriolar satellite protein NOT ISO (MGI:MGI:4457459|PMID:20230748) RGD PMID:20230748 MGI:MGI:4457459 NCBI chr  X:29,562,165...29,602,934
Ensembl chr  X:29,562,165...29,602,925
JBrowse link
G Pibf1 progesterone immunomodulatory binding factor 1 ISO (PMID:21224392) RGD PMID:21224392 NCBI chr15:83,494,110...83,663,202
Ensembl chr15:83,495,377...83,663,143
JBrowse link
G Rab11a RAB11a, member RAS oncogene family ISO (PMID:24561039) RGD PMID:24561039 NCBI chr 8:70,192,975...70,215,719
Ensembl chr 8:70,192,975...70,215,719
JBrowse link
G Rhoa ras homolog family member A ISO (PMID:19635168) RGD PMID:19635168 NCBI chr 8:117,082,440...117,116,244
Ensembl chr 8:117,106,576...117,116,167
JBrowse link
G Smc1a structural maintenance of chromosomes 1A ISO
IEA
(PMID:11590136)
GO_REF:0000107
RGD
Ensembl
PMID:11590136 GO_REF:0000107 NCBI chr  X:21,710,976...21,755,708
Ensembl chr  X:21,711,019...21,755,525
JBrowse link
G Smc3 structural maintenance of chromosomes 3 ISO
IEA
(PMID:11590136)
GO_REF:0000107
RGD
Ensembl
PMID:11590136 GO_REF:0000107 NCBI chr 1:274,310,120...274,352,856
Ensembl chr 1:274,309,758...274,352,854
JBrowse link
G Spice1 spindle and centriole associated protein 1 IEA
IBA
ISS
ISO
GO_REF:0000002
PMID:21873635
GO_REF:0000024
(PMID:20736305)
InterPro
UniProt
RGD
PMID:20736305, PMID:21873635 GO_REF:0000002, GO_REF:0000024, RGD:13792537 NCBI chr11:61,250,649...61,294,116
Ensembl chr11:61,251,696...61,294,022
JBrowse link
G Stag1 stromal antigen 1 ISO (PMID:11590136) RGD PMID:11590136 NCBI chr 8:108,958,099...109,342,738
Ensembl chr 8:108,958,046...109,342,738
JBrowse link
G Stag2 stromal antigen 2 ISO (PMID:11590136) RGD PMID:11590136 NCBI chr  X:128,493,603...128,624,418
Ensembl chr  X:128,493,614...128,624,418
JBrowse link
G Tasor transcription activation suppressor ISO (MGI:MGI:6380343|PMID:31112734) RGD PMID:31112734 MGI:MGI:6380343 NCBI chr16:3,050,506...3,108,168
Ensembl chr16:3,051,449...3,105,531
JBrowse link
G Togaram1 TOG array regulator of axonemal microtubules 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 6:86,713,588...86,780,134
Ensembl chr 6:86,713,604...86,780,147
JBrowse link
G Togaram2 TOG array regulator of axonemal microtubules 2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 6:23,358,762...23,416,386
Ensembl chr 6:23,359,009...23,404,368
JBrowse link
G Tpx2 TPX2, microtubule nucleation factor ISO
IBA
(PMID:26165940)
PMID:21873635
(MGI:MGI:5689196|PMID:26165940)
RGD PMID:26165940, PMID:21873635 MGI:MGI:5689196, RGD:13792537 NCBI chr 3:148,327,965...148,370,187
Ensembl chr 3:148,327,965...148,370,187
JBrowse link
G Wrap73 WD repeat containing, antisense to TP73 ISO (PMID:26545777) RGD PMID:26545777 NCBI chr 5:171,441,471...171,455,795
Ensembl chr 5:171,441,560...171,455,650
JBrowse link
G Xiap X-linked inhibitor of apoptosis IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:128,409,425...128,455,786
Ensembl chr  X:128,409,472...128,453,000
JBrowse link
G Zfp207 zinc finger protein 207 ISO
IBA
(PMID:26388440)
PMID:21873635
(MGI:MGI:5693669|PMID:26388440)
RGD PMID:26388440, PMID:21873635 MGI:MGI:5693669, RGD:13792537 NCBI chr10:67,762,970...67,784,854
Ensembl chr10:67,762,995...67,774,787
JBrowse link
mitotic spindle midzone assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aurkb aurora kinase B ISO
ISS
(PMID:16103226)
GO_REF:0000024
RGD
UniProt
PMID:16103226 GO_REF:0000024 NCBI chr10:55,625,860...55,632,399
Ensembl chr10:55,626,741...55,634,991
JBrowse link
G Kif23 kinesin family member 23 ISO
IBA
(PMID:16103226)
PMID:21873635
RGD PMID:16103226, PMID:21873635 RGD:13792537 NCBI chr 8:66,866,043...66,893,241
Ensembl chr 8:66,866,082...66,893,196
JBrowse link
G Kif4a kinesin family member 4A ISO (PMID:15843429) RGD PMID:15843429 NCBI chr  X:70,461,700...70,561,084
Ensembl chr  X:70,461,718...70,561,189
JBrowse link
G Map10 microtubule-associated protein 10 ISO
IBA
ISS
(PMID:23264731)
PMID:21873635
GO_REF:0000024
RGD
UniProt
PMID:23264731, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr19:58,505,811...58,508,603
Ensembl chr19:58,505,811...58,508,603
JBrowse link
G Prc1 protein regulator of cytokinesis 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:142,087,181...142,108,746
Ensembl chr 1:142,087,208...142,108,746
JBrowse link
G Racgap1 Rac GTPase-activating protein 1 ISO (PMID:16103226) RGD PMID:16103226 NCBI chr 7:141,277,303...141,308,849
Ensembl chr 7:141,277,312...141,307,233
JBrowse link
regulation of mitotic spindle assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccsap centriole, cilia and spindle-associated protein ISO
IBA
(PMID:26562023)
PMID:21873635
RGD PMID:26562023, PMID:21873635 RGD:13792537 NCBI chr19:56,615,326...56,634,031
Ensembl chr19:56,617,399...56,633,633
JBrowse link
G Cep97 centrosomal protein 97 ISO (PMID:17719545) RGD PMID:17719545 NCBI chr11:47,146,409...47,174,460
Ensembl chr11:47,146,308...47,174,713
JBrowse link
G Chmp1a charged multivesicular body protein 1A ISO (PMID:20616062) RGD PMID:20616062 NCBI chr19:56,001,724...56,010,004
Ensembl chr19:56,001,724...56,010,004
JBrowse link
G Chmp1b charged multivesicular body protein 1B ISO (PMID:20616062) RGD PMID:20616062 NCBI chr18:62,923,620...62,926,150 JBrowse link
G Chmp2a charged multivesicular body protein 2A ISO (PMID:20616062) RGD PMID:20616062 NCBI chr 1:65,540,808...65,543,708
Ensembl chr 1:65,541,322...65,543,707
JBrowse link
G Chmp2b charged multivesicular body protein 2B ISO (PMID:20616062) RGD PMID:20616062 NCBI chr11:2,666,405...2,692,213
Ensembl chr11:2,665,285...2,692,198
JBrowse link
G Chmp3 charged multivesicular body protein 3 NOT ISO (PMID:20616062) RGD PMID:20616062 NCBI chr 4:99,449,213...99,496,156
Ensembl chr 4:99,449,111...99,494,423
JBrowse link
G Chmp4b charged multivesicular body protein 4B ISO (PMID:20616062) RGD PMID:20616062 NCBI chr 3:150,188,275...150,227,453
Ensembl chr 3:150,188,455...150,227,405
JBrowse link
G Chmp4c charged multivesicular body protein 4C IEA
ISO
GO_REF:0000107
(PMID:20616062)
Ensembl
RGD
PMID:20616062 GO_REF:0000107 NCBI chr 2:93,574,554...93,641,497
Ensembl chr 2:93,574,559...93,641,497
JBrowse link
G Chmp5 charged multivesicular body protein 5 ISO (PMID:20616062) RGD PMID:20616062 NCBI chr 5:57,267,312...57,284,455
Ensembl chr 5:57,267,312...57,284,448
JBrowse link
G Drg1 developmentally regulated GTP binding protein 1 ISO (PMID:28855639) RGD PMID:28855639 NCBI chr14:83,460,540...83,476,568
Ensembl chr14:83,460,540...83,476,568
JBrowse link
G Hnrnpu heterogeneous nuclear ribonucleoprotein U IEA
IBA
ISS
ISO
GO_REF:0000107
PMID:21873635
GO_REF:0000024
(PMID:21242313)
Ensembl
UniProt
RGD
PMID:21242313, PMID:21873635 GO_REF:0000024, GO_REF:0000107, RGD:13792537 NCBI chr13:96,222,093...96,238,845
Ensembl chr13:96,225,912...96,238,572
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A ISO
IBA
ISS
(PMID:27137183)
PMID:21873635
GO_REF:0000024
RGD
UniProt
PMID:27137183, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr20:4,875,834...4,881,751
Ensembl chr20:4,877,324...4,879,779
JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B ISO
IBA
ISS
(PMID:27137183)
PMID:21873635
GO_REF:0000024
RGD
UniProt
PMID:27137183, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr20:4,877,638...4,880,112
Ensembl chr20:2,699,712...2,701,815
JBrowse link
G LOC108348108 heat shock 70 kDa protein 1A ISS
IBA
GO_REF:0000024
PMID:21873635
UniProt PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr20:2,699,707...2,701,856
Ensembl chr20:4,877,324...4,879,779
Ensembl chr20:4,877,324...4,879,779
JBrowse link
G Pdcd6ip programmed cell death 6 interacting protein NOT ISO (PMID:20616062) RGD PMID:20616062 NCBI chr 8:121,916,233...121,973,145
Ensembl chr 8:121,916,185...121,973,125
JBrowse link
G Plk1 polo-like kinase 1 ISO
IEA
(PMID:22621898)
GO_REF:0000107
RGD
Ensembl
PMID:22621898 GO_REF:0000107 NCBI chr 1:192,115,990...192,125,969
Ensembl chr 1:192,115,966...192,125,989
JBrowse link
G Rcc1 regulator of chromosome condensation 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:150,508,840...150,531,062
Ensembl chr 5:150,509,040...150,525,254
JBrowse link
G Ripor2 RHO family interacting cell polarization regulator 2 ISO (PMID:27556504) RGD PMID:27556504 NCBI chr17:42,324,594...42,549,907
Ensembl chr17:42,324,594...42,422,053
JBrowse link
G Tpr translocated promoter region, nuclear basket protein ISO
IBA
ISS
(PMID:19273613)
PMID:21873635
GO_REF:0000024
RGD
UniProt
PMID:19273613, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr13:67,611,685...67,672,833
Ensembl chr13:67,611,708...67,672,827
JBrowse link
G Vps4b vacuolar protein sorting 4 homolog B ISO (PMID:20616062) RGD PMID:20616062 NCBI chr13:26,825,261...26,850,460
Ensembl chr13:26,825,261...26,850,460
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20028
    cellular process 18800
      cell cycle process 1210
        spindle organization 196
          mitotic spindle organization 122
            mitotic spindle assembly 69
              microtubule anchoring at mitotic spindle pole body 0
              mitotic spindle formation (spindle phase one) + 0
              mitotic spindle midzone assembly + 6
              regulation of mitotic spindle assembly + 21
Path 2
Term Annotations click to browse term
  biological_process 20028
    cellular process 18800
      cellular component organization or biogenesis 6789
        cellular component organization 6534
          organelle organization 4101
            cytoskeleton organization 1461
              microtubule cytoskeleton organization 647
                spindle organization 196
                  spindle assembly 126
                    mitotic spindle assembly 69
                      microtubule anchoring at mitotic spindle pole body 0
                      mitotic spindle formation (spindle phase one) + 0
                      mitotic spindle midzone assembly + 6
                      regulation of mitotic spindle assembly + 21
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.