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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of DNA methylation-dependent heterochromatin assembly
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Accession:GO:0090308 term browser browse the term
Definition:Any process that modulates the rate, frequency, or extent of the repression of transcription by methylation of DNA, leading to the formation of heterochromatin.
Synonyms:broad_synonym: regulation of methylation-dependent chromatin silencing


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regulation of DNA methylation-dependent heterochromatin assembly term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pou5f1 POU class 5 homeobox 1 ISO (PMID:19736317) BHF-UCL PMID:19736317 NCBI chrNW_004936837:827,568...838,933 JBrowse link
negative regulation of DNA methylation-dependent heterochromatin assembly term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aicda activation induced cytidine deaminase ISO (PMID:21496894) UniProtKB PMID:21496894 NCBI chrNW_004936870:25,039...34,601 JBrowse link
G Tet1 tet methylcytosine dioxygenase 1 ISO (PMID:21496894) UniProtKB PMID:21496894 NCBI chrNW_004936521:9,646,581...9,765,244 JBrowse link
positive regulation of DNA methylation-dependent heterochromatin assembly term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf7ip activating transcription factor 7 interacting protein ISO (PMID:27732843) UniProt PMID:27732843 NCBI chrNW_004936587:2,922,855...3,026,773 JBrowse link
G Dnmt1 DNA methyltransferase 1 ISO (PMID:24623306) UniProtKB PMID:24623306 NCBI chrNW_004936659:520,181...565,496 JBrowse link
G Morc2 MORC family CW-type zinc finger 2 ISO (PMID:28581500), (PMID:29211708)
(MGI:MGI:6271895|PMID:29728365)
UniProt PMID:28581500, PMID:29211708, PMID:29728365 MGI:MGI:6271895 NCBI chrNW_004936755:133,315...171,507 JBrowse link
G Mphosph8 M-phase phosphoprotein 8 ISO (PMID:28581500), (PMID:29211708) UniProt PMID:28581500, PMID:29211708 NCBI chrNW_004936720:1,972,063...2,025,283 JBrowse link
G Pphln1 periphilin 1 ISO (PMID:28581500) UniProt PMID:28581500 NCBI chrNW_004936512:1,001,733...1,158,647 JBrowse link
G Resf1 retroelement silencing factor 1 ISO (MGI:MGI:6271895|PMID:29728365) UniProt PMID:29728365 MGI:MGI:6271895 NCBI chrNW_004936607:4,247,824...4,274,410 JBrowse link
G Setdb1 SET domain bifurcated histone lysine methyltransferase 1 ISO (MGI:MGI:5440670|PMID:20164836), (MGI:MGI:6271895|PMID:29728365)
(PMID:24623306), (PMID:27732843)
UniProt PMID:20164836, PMID:24623306, PMID:27732843, PMID:29728365 MGI:MGI:5440670, MGI:MGI:6271895 NCBI chrNW_004936580:1,146,286...1,192,842 JBrowse link
G Tasor transcription activation suppressor ISO (PMID:28581500), (PMID:29211708) UniProt PMID:28581500, PMID:29211708 NCBI chrNW_004936473:7,053,797...7,098,608 JBrowse link
G Trim28 tripartite motif containing 28 ISO (PMID:24623306)
(MGI:MGI:5440670|PMID:20164836)
UniProtKB
UniProt
PMID:20164836, PMID:24623306 MGI:MGI:5440670 NCBI chrNW_004937062:126,832...132,938 JBrowse link
G Znf304 zinc finger protein 304 ISO (PMID:24623306) UniProtKB PMID:24623306 NCBI chrNW_004936897:244,051...253,580 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 11962
    cellular process 11135
      regulation of cellular process 7896
        regulation of cellular component biogenesis 931
          regulation of chromatin assembly 20
            regulation of heterochromatin assembly 18
              regulation of DNA methylation-dependent heterochromatin assembly 13
                negative regulation of DNA methylation-dependent heterochromatin assembly 2
                positive regulation of DNA methylation-dependent heterochromatin assembly 10
Path 2
Term Annotations click to browse term
  biological_process 11962
    metabolic process 7653
      cellular metabolic process 7051
        cellular aromatic compound metabolic process 3743
          nucleobase-containing compound metabolic process 3574
            nucleic acid metabolic process 3288
              RNA metabolic process 2915
                regulation of RNA metabolic process 2500
                  regulation of RNA biosynthetic process 2291
                    negative regulation of RNA biosynthetic process 1068
                      negative regulation of nucleic acid-templated transcription 1066
                        negative regulation of transcription, DNA-templated 1062
                          chromatin organization involved in negative regulation of transcription 59
                            heterochromatin assembly 41
                              regulation of heterochromatin assembly 18
                                regulation of DNA methylation-dependent heterochromatin assembly 13
                                  negative regulation of DNA methylation-dependent heterochromatin assembly 2
                                  positive regulation of DNA methylation-dependent heterochromatin assembly 10
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.