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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of DNA methylation-dependent heterochromatin assembly
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Accession:GO:0090310 term browser browse the term
Definition:Any process that decreases the rate, frequency, or extent of the repression of transcription by methylation of DNA, leading to the formation of heterochromatin.
Synonyms:broad_synonym: negative regulation of methylation-dependent chromatin silencing


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negative regulation of DNA methylation-dependent heterochromatin assembly term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aicda activation induced cytidine deaminase ISO (PMID:21496894) UniProtKB PMID:21496894 NCBI chrNW_004936870:25,039...34,601 JBrowse link
G Tet1 tet methylcytosine dioxygenase 1 ISO (PMID:21496894) UniProtKB PMID:21496894 NCBI chrNW_004936521:9,646,581...9,765,244 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 11962
    metabolic process 7653
      negative regulation of metabolic process 2541
        negative regulation of macromolecule metabolic process 2288
          negative regulation of DNA methylation-dependent heterochromatin assembly 2
Path 2
Term Annotations click to browse term
  biological_process 11962
    metabolic process 7653
      cellular metabolic process 7051
        cellular aromatic compound metabolic process 3743
          nucleobase-containing compound metabolic process 3574
            nucleic acid metabolic process 3288
              RNA metabolic process 2915
                RNA biosynthetic process 2371
                  regulation of RNA biosynthetic process 2291
                    regulation of nucleic acid-templated transcription 2286
                      negative regulation of nucleic acid-templated transcription 1066
                        negative regulation of transcription, DNA-templated 1062
                          chromatin organization involved in negative regulation of transcription 59
                            heterochromatin assembly 41
                              regulation of heterochromatin assembly 18
                                regulation of DNA methylation-dependent heterochromatin assembly 13
                                  negative regulation of DNA methylation-dependent heterochromatin assembly 2
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.