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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of cell aging
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Accession:GO:0090344 term browser browse the term
Definition:Any process that decreases the rate, frequency, or extent of cell aging. Cell aging is the progression of the cell from its inception to the end of its lifespan.

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negative regulation of cell aging term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxm1 forkhead box M1 IEA
ISO		 GO_REF:0000107
(PMID:19696738)		 Ensembl
RGD		 PMID:19696738 GO_REF:0000107 NCBI chr 4:161,685,236...161,697,633
Ensembl chr 4:161,685,258...161,696,305 		JBrowse link
G Fzr1 fizzy and cell division cycle 20 related 1 ISO (MGI:5009768|PMID:21241890) RGD PMID:21241890 MGI:5009768 NCBI chr 7:11,201,690...11,213,614
Ensembl chr 7:11,201,690...11,213,613 		JBrowse link
G Marchf5 membrane associated ring-CH-type finger 5 ISO (PMID:20103533) RGD PMID:20103533 NCBI chr 1:255,842,642...255,864,131
Ensembl chr 1:255,842,783...255,863,142 		JBrowse link
G Mif macrophage migration inhibitory factor ISO (PMID:10562313) RGD PMID:10562313 NCBI chr20:13,715,219...13,732,980
Ensembl chr20:13,732,198...13,732,859 		JBrowse link
G Pten phosphatase and tensin homolog ISO (MGI:5009768|PMID:21241890) RGD PMID:21241890 MGI:5009768 NCBI chr 1:251,421,814...251,487,634
Ensembl chr 1:251,421,596...251,487,832 		JBrowse link
G Wnt1 Wnt family member 1 ISO (PMID:16501043) RGD PMID:16501043 NCBI chr 7:140,464,999...140,469,046
Ensembl chr 7:140,464,999...140,469,046 		JBrowse link
negative regulation of cellular senescence term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase ISO MGI:104738 (MGI:5449665|PMID:22729085) RGD PMID:22729085 MGI:5449665 NCBI chr 3:10,041,820...10,145,076
Ensembl chr 3:10,041,826...10,144,388 		JBrowse link
G Akt3 AKT serine/threonine kinase 3 ISO
IEA		 (PMID:25323119)
GO_REF:0000107		 RGD
Ensembl		 PMID:25323119 GO_REF:0000107 NCBI chr13:95,076,308...95,348,913
Ensembl chr13:95,081,390...95,348,913 		JBrowse link
G Bcl2l12 BCL2 like 12 ISO (MGI:4834958|PMID:20837658) RGD PMID:20837658 MGI:4834958 NCBI chr 1:100,984,550...100,993,269
Ensembl chr 1:100,984,550...100,993,269 		JBrowse link
G Bcl6 BCL6, transcription repressor ISO MGI:2158436 (MGI:5469797|PMID:23209284) RGD PMID:23209284 MGI:5469797 NCBI chr11:80,255,790...80,279,075
Ensembl chr11:80,255,790...80,279,075 		JBrowse link
G Cdk6 cyclin-dependent kinase 6 ISO (PMID:17420273) RGD PMID:17420273 NCBI chr 4:27,781,728...27,969,653
Ensembl chr 4:27,785,647...27,966,398 		JBrowse link
G Fbxo5 F-box protein 5 ISO (PMID:17875940) RGD PMID:17875940 NCBI chr 1:42,461,277...42,467,646
Ensembl chr 1:42,461,291...42,467,586 		JBrowse link
G Hmga2 high mobility group AT-hook 2 ISO (MGI:5582375|PMID:23072816) RGD PMID:23072816 MGI:5582375 NCBI chr 7:65,159,944...65,275,408
Ensembl chr 7:65,159,944...65,275,408 		JBrowse link
G LOC100912427 nuclease-sensitive element-binding protein 1-like ISO (MGI:6158172|PMID:29712925) RGD PMID:29712925 MGI:6158172 NCBI chr 1:186,635,408...186,641,503
Ensembl chr 1:186,640,425...186,641,393 		JBrowse link
G Map3k3 mitogen activated protein kinase kinase kinase 3 ISO (PMID:28640956) RGD PMID:28640956 NCBI chr10:94,280,703...94,349,372
Ensembl chr10:94,280,703...94,349,368 		JBrowse link
G Nampt nicotinamide phosphoribosyltransferase IDA RGD PMID:28125705 RGD:13781884 NCBI chr 6:52,122,085...52,156,473
Ensembl chr 6:52,122,085...52,156,472 		JBrowse link
G Plk2 polo-like kinase 2 ISO (MGI:6120300|PMID:27908889) RGD PMID:27908889 MGI:6120300 NCBI chr 2:41,911,143...41,916,901
Ensembl chr 2:41,911,131...41,916,901 		JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit IMP RGD PMID:22981234 RGD:8696027 NCBI chr11:89,293,547...89,510,948
Ensembl chr11:89,293,696...89,510,871 		JBrowse link
G Rbl1 RB transcriptional corepressor like 1 ISO (PMID:28595801) RGD PMID:28595801 NCBI chr 3:153,263,692...153,321,351
Ensembl chr 3:153,263,692...153,321,352 		JBrowse link
G Sirt1 sirtuin 1 ISO
IEA		 (PMID:20203304), (PMID:20424141)
GO_REF:0000107		 RGD
Ensembl		 PMID:20203304, PMID:20424141 GO_REF:0000107 NCBI chr20:26,831,971...26,851,587
Ensembl chr20:26,833,357...26,852,199 		JBrowse link
G Slc30a10 solute carrier family 30, member 10 ISO (PMID:22427991) RGD PMID:22427991 NCBI chr13:103,396,295...103,406,759
Ensembl chr13:103,396,314...103,410,363 		JBrowse link
G Terf2 telomeric repeat binding factor 2 ISO (PMID:11927518) RGD PMID:11927518 NCBI chr19:39,271,992...39,301,506
Ensembl chr19:39,272,499...39,300,893 		JBrowse link
G Tert telomerase reverse transcriptase ISO (PMID:11313459), (PMID:11927518) RGD PMID:11313459, PMID:11927518 NCBI chr 1:32,250,876...32,275,330
Ensembl chr 1:32,251,714...32,272,476 		JBrowse link
G Tp63 tumor protein p63 ISO (PMID:19451233) RGD PMID:19451233 NCBI chr11:78,234,853...78,456,559
Ensembl chr11:78,234,800...78,456,501 		JBrowse link
G Twist1 twist family bHLH transcription factor 1 ISO (PMID:17690110) RGD PMID:17690110 NCBI chr 6:53,401,241...53,403,235
Ensembl chr 6:53,401,109...53,403,214 		JBrowse link
G Ybx1 Y box binding protein 1 ISS
IEA		 GO_REF:0000024
GO_REF:0000107		 UniProt
Ensembl		 GO_REF:0000024, GO_REF:0000107 NCBI chr 5:138,319,754...138,336,721
Ensembl chr 5:138,319,762...138,336,475 		JBrowse link
G Zkscan3 zinc finger with KRAB and SCAN domains 3 ISO (PMID:23434374) RGD PMID:23434374 NCBI chr17:45,247,724...45,263,422
Ensembl chr17:45,247,776...45,263,418 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20020
    negative regulation of biological process 5689
      negative regulation of cellular process 5156
        negative regulation of cell aging 27
          negative regulation of cellular senescence 21
          negative regulation of replicative senescence 0
Path 2
Term Annotations click to browse term
  biological_process 20020
    biological regulation 13769
      regulation of biological process 13071
        regulation of developmental process 2646
          negative regulation of developmental process 1015
            negative regulation of cell aging 27
              negative regulation of cellular senescence 21
              negative regulation of replicative senescence 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.