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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of heart induction
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Accession:GO:0090381 term browser browse the term
Definition:Any process that modulates the rate, frequency, or extent of heart induction. Heart induction is the close range interaction between mesoderm and endoderm or ectoderm that causes cells to change their fates and specify the development of the heart.


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negative regulation of heart induction by canonical Wnt signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wnt3a Wnt family member 3A ISO (PMID:19736317) RGD PMID:19736317 NCBI chr10:45,598,898...45,643,151
Ensembl chr10:45,598,912...45,638,035
JBrowse link
positive regulation of heart induction by negative regulation of canonical Wnt signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 ISO (MGI:3835736|PMID:18297060) RGD PMID:18297060 MGI:3835736 NCBI chr 1:248,952,896...248,956,579
Ensembl chr 1:248,895,738...248,898,607
JBrowse link
G Mesp1 mesoderm posterior bHLH transcription factor 1 ISO (MGI:3835736|PMID:18297060) RGD PMID:18297060 MGI:3835736 NCBI chr 1:141,532,390...141,533,908
Ensembl chr 1:141,532,390...141,533,908
JBrowse link
G Wnt11 Wnt family member 11 ISO UniProtKB:P22725 (MGI:5424267|PMID:22569553) RGD PMID:22569553 MGI:5424267 NCBI chr 1:163,794,136...163,813,756
Ensembl chr 1:163,797,660...163,813,756
JBrowse link
G Wnt5a Wnt family member 5A IEA
ISO
GO_REF:0000107
UniProtKB:P48615 (MGI:5424267|PMID:22569553)
Ensembl
RGD
PMID:22569553 GO_REF:0000107, MGI:5424267 NCBI chr16:4,469,451...4,490,271
Ensembl chr16:4,469,468...4,489,860
JBrowse link
regulation of heart induction by regulation of canonical Wnt signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pou5f1 POU class 5 homeobox 1 ISO (PMID:19736317) RGD PMID:19736317 NCBI chr20:3,747,231...3,751,994
Ensembl chr20:3,747,221...3,751,994
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20020
    multicellular organismal process 9047
      regulation of multicellular organismal process 2916
        regulation of heart induction 6
          negative regulation of heart induction + 1
          positive regulation of heart induction + 4
          regulation of heart induction by canonical Wnt signaling pathway + 6
          regulation of heart induction by regulation of canonical Wnt signaling pathway + 5
Path 2
Term Annotations click to browse term
  biological_process 20020
    developmental process 6826
      anatomical structure development 6268
        multicellular organism development 5743
          system development 5279
            animal organ development 4033
              animal organ morphogenesis 1151
                animal organ formation 76
                  regulation of animal organ formation 34
                    organ induction 29
                      heart induction 11
                        regulation of heart induction 6
                          negative regulation of heart induction + 1
                          positive regulation of heart induction + 4
                          regulation of heart induction by canonical Wnt signaling pathway + 6
                          regulation of heart induction by regulation of canonical Wnt signaling pathway + 5
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.