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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of excitatory postsynaptic potential
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Accession:GO:0090394 term browser browse the term
Definition:Any process that prevents the establishment or decreases the extent of the excitatory postsynaptic potential (EPSP) which is a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential.
Synonyms:exact_synonym: negative regulation of excitatory post-synaptic membrane potential;   reduction of excitatory postsynaptic membrane potential
 related_synonym: negative regulation of EPSP


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negative regulation of excitatory postsynaptic potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cbln1 cerebellin 1 precursor JBrowse link 19 20,607,507 20,611,316 RGD:1624291
G Celf4 CUGBP, Elav-like family member 4 JBrowse link 18 17,689,090 18,079,835 RGD:1624291
G Eif4a3 eukaryotic translation initiation factor 4A3 JBrowse link 10 108,415,201 108,425,195 RGD:10044262
G Lrrk2 leucine-rich repeat kinase 2 JBrowse link 7 132,857,311 133,018,549 RGD:1624291
G Mtmr2 myotubularin related protein 2 JBrowse link 8 12,283,471 12,334,014 RGD:8553482
G Nlgn3 neuroligin 3 JBrowse link X 71,199,390 71,227,460 RGD:1624291
RGD:1600115
G Npy2r neuropeptide Y receptor Y2 JBrowse link 2 181,528,949 181,538,145 RGD:1642608
G Prkn parkin RBR E3 ubiquitin protein ligase JBrowse link 1 48,880,015 50,069,998 RGD:10413844
G Pten phosphatase and tensin homolog JBrowse link 1 251,421,814 251,487,634 RGD:1624291
G S1pr2 sphingosine-1-phosphate receptor 2 JBrowse link 8 21,984,914 21,995,806 RGD:1624291
G Tmem25 transmembrane protein 25 JBrowse link 8 49,100,759 49,106,258 RGD:1624291
RGD:13792537
negative regulation of mini excitatory postsynaptic potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Syne1 spectrin repeat containing nuclear envelope protein 1 JBrowse link 1
1
41,608,287
41,844,840
41,763,591
42,086,662
RGD:13209020

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19858
    multicellular organismal process 8951
      negative regulation of multicellular organismal process 1381
        negative regulation of nervous system process 33
          negative regulation of excitatory postsynaptic potential 12
            negative regulation of acetylcholine-gated cation channel activity 0
            negative regulation of mini excitatory postsynaptic potential 1
Path 2
Term Annotations click to browse term
  biological_process 19858
    cellular process 18618
      cell communication 7631
        cell-cell signaling 1794
          synaptic signaling 913
            trans-synaptic signaling 885
              anterograde trans-synaptic signaling 876
                chemical synaptic transmission 876
                  chemical synaptic transmission, postsynaptic 126
                    excitatory postsynaptic potential 117
                      modulation of excitatory postsynaptic potential 58
                        negative regulation of excitatory postsynaptic potential 12
                          negative regulation of acetylcholine-gated cation channel activity 0
                          negative regulation of mini excitatory postsynaptic potential 1
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.