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ONTOLOGY REPORT - ANNOTATIONS


Term:RNA phosphodiester bond hydrolysis, endonucleolytic
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Accession:GO:0090502 term browser browse the term
Definition:The chemical reactions and pathways involving the hydrolysis of internal 3',5'-phosphodiester bonds in one or two strands of ribonucleotides.


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RNA phosphodiester bond hydrolysis, endonucleolytic term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AC118772.1 RGD:1600115
G Ago1 argonaute RISC component 1 JBrowse link 5 144,444,390 144,479,430 RGD:1600115
G Ago2 argonaute RISC catalytic component 2 JBrowse link 7 114,339,607 114,377,277 RGD:1600115
G Ago3 argonaute RISC catalytic component 3 JBrowse link 5 144,355,792 144,436,509 RGD:1600115
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 JBrowse link 15 27,849,943 27,852,083 RGD:1600115
G Cpsf3 cleavage and polyadenylation specific factor 3 JBrowse link 6 43,363,792 43,391,712 RGD:1600115
G Dbr1 debranching RNA lariats 1 JBrowse link 8 107,826,690 107,838,186 RGD:1600115
G Dgcr8 DGCR8 microprocessor complex subunit JBrowse link 11 86,852,682 86,885,233 RGD:1600115
G Dicer1 dicer 1 ribonuclease III JBrowse link 6 128,388,084 128,453,234 RGD:1624291
G Drosha drosha ribonuclease III JBrowse link 2 62,887,267 63,000,307 RGD:1600115
G Edc3 enhancer of mRNA decapping 3 JBrowse link 8 62,482,126 62,527,665 RGD:1600115
G Endog endonuclease G JBrowse link 3 8,741,833 8,744,414 RGD:1600115
G Endou endonuclease, poly(U)-specific JBrowse link 7 139,202,342 139,223,022 RGD:1600115
G Endov endonuclease V JBrowse link 10 108,630,723 108,646,679 RGD:1600115
G Ern1 endoplasmic reticulum to nucleus signaling 1 JBrowse link 10 94,588,555 94,682,072 RGD:1600115
G Ern2 endoplasmic reticulum to nucleus signaling 2 JBrowse link 1 192,126,023 192,142,865 RGD:1600115
G Exog exo/endonuclease G JBrowse link 8 128,133,398 128,153,110 RGD:1600115
G Fen1 flap structure-specific endonuclease 1 JBrowse link 1 226,251,516 226,256,160 RGD:1600115
G Lactb2 lactamase, beta 2 JBrowse link 5 4,982,348 5,005,111 RGD:1624291
RGD:1600115
G LOC103690354 ribonuclease pancreatic beta-type JBrowse link 15 28,073,963 28,075,677 RGD:1600115
G LOC103694852 ribonuclease K6-like RGD:1600115
G LOC103694853 ribonuclease pancreatic gamma-type RGD:1600115
G LOC688828 similar to Nucleoside diphosphate-linked moiety X motif 16 (Nudix motif 16) JBrowse link 8 113,687,983 113,689,657 RGD:1600115
G Mrpl44 mitochondrial ribosomal protein L44 JBrowse link 9 85,542,763 85,547,814 RGD:1600115
G Nob1 NIN1 (RPN12) binding protein 1 homolog JBrowse link 19 38,397,466 38,409,924 RGD:1600115
G Nudt16 nudix hydrolase 16 JBrowse link 8 113,673,069 113,675,124 RGD:1624291
G Nudt16l1 nudix hydrolase 16 like 1 JBrowse link 10 10,829,866 10,831,782 RGD:1600115
G Piwil1 piwi-like RNA-mediated gene silencing 1 JBrowse link 12 31,608,641 31,629,961 RGD:1600115
G Piwil2 piwi-like RNA-mediated gene silencing 2 JBrowse link 15 52,037,693 52,116,277 RGD:1600115
G Piwil4 piwi-like RNA-mediated gene silencing 4 JBrowse link 8 13,208,774 13,251,970 RGD:1600115
G Pop1 POP1 homolog, ribonuclease P/MRP subunit JBrowse link 7 73,270,403 73,298,209 RGD:13792537
G Pop4 POP4 homolog, ribonuclease P/MRP subunit JBrowse link 1 94,661,127 94,669,461 RGD:1600115
G Pop5 POP5 homolog, ribonuclease P/MRP subunit JBrowse link 12 47,138,346 47,143,152 RGD:1600115
G Pop7 POP7 homolog, ribonuclease P/MRP subunit JBrowse link 12 22,259,713 22,260,754 RGD:13792537
G Prorp protein only RNase P catalytic subunit JBrowse link 6 76,079,880 76,171,298 RGD:1600115
G Rida reactive intermediate imine deaminase A homolog JBrowse link 7 73,256,506 73,270,308 RGD:1600115
G Rnase1 ribonuclease A family member 1, pancreatic RGD:1600115
G Rnase1l1 ribonuclease, RNase A family, 1-like 1 (pancreatic) JBrowse link 15 28,043,491 28,045,098 RGD:1600115
G Rnase1l2 ribonuclease, RNase A family, 1-like 2 (pancreatic) JBrowse link 15 28,127,147 28,128,797 RGD:1600115
G Rnase6 ribonuclease A family member k6 JBrowse link 15 28,080,307 28,084,269 RGD:1600115
G Rnaseh1 ribonuclease H1 JBrowse link 6 47,916,188 47,925,582 RGD:13792537
G Rnaseh2a ribonuclease H2, subunit A JBrowse link 19 26,074,980 26,084,780 RGD:1600115
G Rnaseh2b ribonuclease H2, subunit B JBrowse link 15 45,422,010 45,472,792 RGD:1600115
G Rnasek ribonuclease K JBrowse link 10 56,848,367 56,850,085 RGD:1600115
G Rnaset2 ribonuclease T2 JBrowse link 1 53,174,879 53,192,048 RGD:1600115
G Rpp14 ribonuclease P/MRP subunit p14 JBrowse link 15 18,625,963 18,636,157 RGD:1600115
G Rpp21 ribonuclease P/MRP subunit p21 JBrowse link 20 2,515,541 2,517,471 RGD:1600115
G Rpp25 ribonuclease P and MRP subunit p25 JBrowse link 8 62,283,336 62,284,716 RGD:1600115
G Rpp30 ribonuclease P/MRP subunit p30 JBrowse link 1 254,697,247 254,720,093 RGD:13792537
G Rpp38 ribonuclease P/MRP subunit p38 JBrowse link 17 78,915,450 78,919,144 RGD:1600115
G Rpp40 ribonuclease P/MRP subunit p40 JBrowse link 17 29,638,647 29,647,709 RGD:1600115
G Slfn13 schlafen family member 13 JBrowse link 10 70,326,157 70,343,024 RGD:1600115
G Slfn14 schlafen family member 14 JBrowse link 10 70,493,340 70,504,810 RGD:1624291
G Smg6 SMG6 nonsense mediated mRNA decay factor JBrowse link 10
10
61,526,024
61,771,912
61,542,583
62,007,030
RGD:1600115
G Snd1 staphylococcal nuclease and tudor domain containing 1 JBrowse link 4 55,772,377 56,171,669 RGD:1600115
G Tsen2 tRNA splicing endonuclease subunit 2 JBrowse link 4 147,455,506 147,490,869 RGD:1600115
G Tsen34 tRNA splicing endonuclease subunit 34 JBrowse link 1 64,023,924 64,031,756 RGD:1600115
G Tsen34l1 tRNA splicing endonuclease subunit 34-like 1 JBrowse link 1 64,092,224 64,100,061 RGD:1600115
G Tsn translin JBrowse link 13 34,240,809 34,251,671 RGD:1600115
G Tsnax translin-associated factor X JBrowse link 19 57,771,539 57,785,567 RGD:1600115
G Ybey ybeY metalloendoribonuclease JBrowse link 20 12,917,111 12,926,587 RGD:1600115
G Zc3h12a zinc finger CCCH type containing 12A JBrowse link 5 143,111,342 143,120,131 RGD:1624291
RGD:1600115
cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bop1 BOP1 ribosomal biogenesis factor JBrowse link 7 117,514,529 117,538,342 RGD:1624291
G Nol9 nucleolar protein 9 JBrowse link 5 169,213,076 169,233,173 RGD:13792537
G Npm1 nucleophosmin 1 JBrowse link 10 18,080,949 18,091,062 RGD:11535027
endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abt1 activator of basal transcription 1 JBrowse link 17 43,946,118 43,948,224 RGD:13792537
G Fcf1 FCF1 rRNA-processing protein JBrowse link 6 108,796,182 108,808,051 RGD:1624291
G Rcl1 RNA terminal phosphate cyclase-like 1 JBrowse link 1 247,228,012 247,272,369 RGD:1624291
G Utp23 UTP23, small subunit processome component JBrowse link 7 91,384,329 91,389,605 RGD:1624291
endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abt1 activator of basal transcription 1 JBrowse link 17 43,946,118 43,948,224 RGD:13792537
G AC135409.1 RGD:13792537
G Fcf1 FCF1 rRNA-processing protein JBrowse link 6 108,796,182 108,808,051 RGD:1624291
G Kri1 KRI1 homolog JBrowse link 8 22,301,025 22,317,049 RGD:13792537
G Rcl1 RNA terminal phosphate cyclase-like 1 JBrowse link 1 247,228,012 247,272,369 RGD:1624291
G Rps21 ribosomal protein S21 JBrowse link 3 175,629,176 175,630,198 RGD:13792537
G Rrs1 ribosome biogenesis regulator 1 homolog JBrowse link 5 9,430,710 9,432,343 RGD:13792537
endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bms1 BMS1 ribosome biogenesis factor JBrowse link 4 150,433,567 150,471,783 RGD:13792537
G Rcl1 RNA terminal phosphate cyclase-like 1 JBrowse link 1 247,228,012 247,272,369 RGD:13792537
G Tsr1 TSR1, ribosome maturation factor JBrowse link 10 61,746,070 61,757,518 RGD:13792537
endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AC135409.1 RGD:13792537
G Rps21 ribosomal protein S21 JBrowse link 3 175,629,176 175,630,198 RGD:13792537
endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abt1 activator of basal transcription 1 JBrowse link 17 43,946,118 43,948,224 RGD:13792537
mitochondrial tRNA 3'-trailer cleavage, endonucleolytic term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Elac2 elaC ribonuclease Z 2 JBrowse link 10 51,478,378 51,501,167 RGD:1600115
RGD:13792537
RGD:1624291
tRNA 3'-trailer cleavage, endonucleolytic term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Elac1 elaC ribonuclease Z 1 JBrowse link 18 69,706,522 69,723,869 RGD:13792537

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19439
    metabolic process 11638
      organic substance metabolic process 11027
        macromolecule metabolic process 9491
          nucleic acid metabolic process 4784
            nucleic acid phosphodiester bond hydrolysis 264
              RNA phosphodiester bond hydrolysis 158
                RNA phosphodiester bond hydrolysis, endonucleolytic 77
                  endonucleolytic cleavage involved in rRNA processing + 13
                  endonucleolytic cleavage involved in tRNA processing + 2
                  snoRNA 3'-end cleavage 0
Path 2
Term Annotations click to browse term
  biological_process 19439
    metabolic process 11638
      cellular metabolic process 10639
        cellular aromatic compound metabolic process 5503
          nucleobase-containing compound metabolic process 5274
            nucleic acid metabolic process 4784
              RNA metabolic process 4296
                RNA phosphodiester bond hydrolysis 158
                  RNA phosphodiester bond hydrolysis, endonucleolytic 77
                    endonucleolytic cleavage involved in rRNA processing + 13
                    endonucleolytic cleavage involved in tRNA processing + 2
                    snoRNA 3'-end cleavage 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.