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ONTOLOGY REPORT - ANNOTATIONS


Term:protein linear polyubiquitination
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Accession:GO:0097039 term browser browse the term
Definition:A protein ubiquitination process in which a linear polymer of ubiquitin, formed by the amino-terminal methionine (M1) of one ubiquitin molecule and by the carboxy-terminal glycine (G76) of the next, is added to a protein.
Synonyms:narrow_synonym: M1 linkage


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protein linear polyubiquitination term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rbck1 RANBP2-type and C3HC4-type zinc finger containing 1 IEA
IBA
ISO
ISS
GO_REF:0000107
PMID:21873635
(PMID:21455173), (PMID:21455180), (PMID:21455181), (PMID:23453807)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:21455173, PMID:21455180, PMID:21455181, PMID:23453807, PMID:21873635 GO_REF:0000024, GO_REF:0000107, RGD:13792537 NCBI chr 3:147,793,014...147,809,941
Ensembl chr 3:147,793,017...147,809,919
JBrowse link
G Rnf31 ring finger protein 31 ISO (PMID:21455173), (PMID:21455180), (PMID:21455181), (PMID:23453807) RGD PMID:21455173, PMID:21455180, PMID:21455181, PMID:23453807 NCBI chr15:34,270,037...34,282,385
Ensembl chr15:34,270,648...34,282,495
JBrowse link
G Sharpin SHANK-associated RH domain interactor ISS
IBA
ISO
GO_REF:0000024
PMID:21873635
(PMID:21455173), (PMID:21455180), (PMID:21455181)
UniProt
RGD
PMID:21455173, PMID:21455180, PMID:21455181, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 7:117,413,151...117,417,455
Ensembl chr 7:117,413,152...117,417,363
JBrowse link
positive regulation of protein linear polyubiquitination term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prkn parkin RBR E3 ubiquitin protein ligase ISO UniProtKB:Q96EP0|UniProtKB:Q9BYM8 (PMID:23453807)
(MGI:5495588|PMID:23453807)
RGD PMID:23453807 MGI:5495588 NCBI chr 1:48,880,015...50,069,998 JBrowse link
G Xiap X-linked inhibitor of apoptosis ISO
IEA
(PMID:21931591)
GO_REF:0000107
RGD
Ensembl
PMID:21931591 GO_REF:0000107 NCBI chr  X:128,409,425...128,455,786
Ensembl chr  X:128,409,472...128,453,000
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20020
    metabolic process 12263
      cellular metabolic process 11073
        cellular macromolecule metabolic process 8548
          cellular protein metabolic process 5564
            cellular protein modification process 3948
              protein modification by small protein conjugation or removal 951
                protein modification by small protein conjugation 815
                  protein ubiquitination 766
                    protein polyubiquitination 241
                      protein linear polyubiquitination 5
                        negative regulation of protein linear polyubiquitination 0
                        positive regulation of protein linear polyubiquitination 2
                        regulation of protein linear polyubiquitination + 2
Path 2
Term Annotations click to browse term
  biological_process 20020
    metabolic process 12263
      organic substance metabolic process 11643
        macromolecule metabolic process 10077
          protein metabolic process 6221
            protein modification process 3948
              cellular protein modification process 3948
                protein modification by small protein conjugation or removal 951
                  protein modification by small protein conjugation 815
                    protein ubiquitination 766
                      protein polyubiquitination 241
                        protein linear polyubiquitination 5
                          negative regulation of protein linear polyubiquitination 0
                          positive regulation of protein linear polyubiquitination 2
                          regulation of protein linear polyubiquitination + 2
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.