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Term:centralspindlin complex
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Accession:GO:0097149 term browser browse the term
Definition:A heterotetrameric protein complex playing a key role in the formation of the central spindle in mitosis. Made up of two molecules each of a mitotic kinesin (ZEN-4 in Caenorhabditis elegans or MKLP1 in mammals) and of two molecules each of a GTPase activating protein (GAP) factor (CYK-4 in Caenorhabditis elegans or MgcRacGAP in mammals).

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centralspindlin complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ect2 epithelial cell transforming 2 JBrowse link 2 112,769,385 112,831,476 RGD:1624291
G Kif23 kinesin family member 23 JBrowse link 8 66,866,043 66,893,241 RGD:1624291
G Racgap1 Rac GTPase-activating protein 1 JBrowse link 7 141,277,303 141,308,849 RGD:1624291

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Path 1
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  cellular_component 19843
    protein-containing complex 5779
      centralspindlin complex 3
Path 2
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  cellular_component 19843
    cellular anatomical entity 19457
      organelle 12557
        intracellular organelle 12030
          intracellular non-membrane-bounded organelle 4622
            cytoskeleton 2079
              microtubule cytoskeleton 1224
                spindle 338
                  mitotic spindle 124
                    centralspindlin complex 3
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.