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ONTOLOGY REPORT - ANNOTATIONS


Term:amelogenesis
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Accession:GO:0097186 term browser browse the term
Definition:The process whose specific outcome is the formation of tooth enamel, occurring in two stages: secretory stage and maturation stage.
Synonyms:exact_synonym: enamel development


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amelogenesis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf2 activating transcription factor 2 IDA RGD PMID:15218628 RGD:10053659 NCBI chr 3:60,721,137...60,795,951
Ensembl chr 3:60,721,135...60,795,951
JBrowse link
G Csf3r colony stimulating factor 3 receptor IEP RGD PMID:10206335 RGD:5134351 NCBI chr 5:144,031,353...144,051,966
Ensembl chr 5:144,031,402...144,051,600
JBrowse link
G Dspp dentin sialophosphoprotein ISO MGI:2653208 (MGI:5912858|PMID:25027178) RGD PMID:25027178 MGI:5912858 NCBI chr14:6,926,972...6,933,079
Ensembl chr14:6,926,976...6,933,070
JBrowse link
G Enam enamelin IBA
ISO
PMID:21873635
MGI:3055582|MGI:3055586|MGI:3055587|MGI:3796583 (MGI:3530197|PMID:15649948), (MGI:3796449|PMID:18252720), (MGI:5634640|PMID:22813216), (MGI:5647983|PMID:24603688)
RGD PMID:15649948, PMID:18252720, PMID:22813216, PMID:24603688, PMID:21873635 MGI:3530197, MGI:3796449, MGI:5634640, MGI:5647983, RGD:13792537 NCBI chr14:21,194,635...21,219,529
Ensembl chr14:21,194,664...21,219,454
JBrowse link
G Klk4 kallikrein-related peptidase 4 ISO
IBA
(PMID:15235027)
MGI:4355346 (MGI:4354666|PMID:19578120), (MGI:5008529|PMID:21454549), (MGI:5502300|PMID:22243248)
PMID:21873635
RGD PMID:15235027, PMID:19578120, PMID:21454549, PMID:22243248, PMID:21873635 MGI:4354666, MGI:5008529, MGI:5502300, RGD:13792537 NCBI chr 1:99,828,944...99,834,642
Ensembl chr 1:99,829,351...99,834,216
JBrowse link
G Klk5 kallikrein related-peptidase 5 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:99,781,291...99,793,745
Ensembl chr 1:99,781,237...99,786,330
JBrowse link
G Mmp20 matrix metallopeptidase 20 IBA
ISO
PMID:21873635
MGI:2447874 (MGI:3522683|PMID:15557396), (MGI:5008529|PMID:21454549), (MGI:5502300|PMID:22243248)
RGD PMID:15557396, PMID:21454549, PMID:22243248, PMID:21873635 MGI:3522683, MGI:5008529, MGI:5502300, RGD:13792537 NCBI chr 8:5,823,147...5,875,555
Ensembl chr 8:5,833,359...5,875,232
JBrowse link
G Perp p53 apoptosis effector related to PMP22 ISO MGI:2683069 (MGI:5317035|PMID:21285247) RGD PMID:21285247 MGI:5317035 NCBI chr 1:14,224,392...14,236,838
Ensembl chr 1:14,224,393...14,236,846
JBrowse link
G Relt RELT, TNF receptor ISO
IBA
(PMID:30506946)
(MGI:6368096|PMID:30506946)
PMID:21873635
RGD PMID:30506946, PMID:21873635 MGI:6368096, RGD:13792537 NCBI chr 1:165,884,407...165,902,022
Ensembl chr 1:165,884,407...165,901,923
JBrowse link
G Slc24a4 solute carrier family 24 member 4 ISO (MGI:5520028|PMID:23375655) RGD PMID:23375655 MGI:5520028 NCBI chr 6:126,015,799...126,158,727
Ensembl chr 6:126,018,841...126,153,867
JBrowse link
enamel mineralization term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Amelx amelogenin, X-linked ISO (PMID:1916828)
(PMID:21653221)
RGD PMID:1916828, PMID:21653221 NCBI chr  X:26,439,197...26,450,495
Ensembl chr  X:26,439,197...26,450,495
JBrowse link
G Cnnm4 cyclin and CBS domain divalent metal cation transport mediator 4 ISO (MGI:5559016|PMID:24339795) RGD PMID:24339795 MGI:5559016 NCBI chr 9:43,049,587...43,088,690
Ensembl chr 9:43,049,587...43,088,702
JBrowse link
G Fam20a FAM20A, golgi associated secretory pathway pseudokinase ISO
IBA
(PMID:21549343), (PMID:21990045), (PMID:23468644)
MGI:5432376 (MGI:5432245|PMID:22732358)
PMID:21873635
RGD PMID:21549343, PMID:21990045, PMID:22732358, PMID:23468644, PMID:21873635 MGI:5432245, RGD:13792537 NCBI chr10:97,962,467...98,017,171
Ensembl chr10:97,962,693...98,018,014
JBrowse link
G Fam20c FAM20C, golgi associated secretory pathway kinase IBA
ISO
PMID:21873635
MGI:5432377 (MGI:5432245|PMID:22732358)
RGD PMID:22732358, PMID:21873635 MGI:5432245, RGD:13792537 NCBI chr12:17,913,771...17,972,733
Ensembl chr12:17,913,767...17,972,737
JBrowse link
G Foxo1 forkhead box O1 IEP RGD PMID:25183529 RGD:10044263 NCBI chr 2:141,451,234...141,527,016
Ensembl chr 2:141,451,234...141,527,016
JBrowse link
G Itgb6 integrin subunit beta 6 ISO MGI:1926484 (MGI:5507902|PMID:23264742) RGD PMID:23264742 MGI:5507902 NCBI chr 3:46,652,624...46,775,362
Ensembl chr 3:46,652,623...46,726,958
JBrowse link
G Msx2 msh homeobox 2 IEA
ISO
GO_REF:0000107
MGI:1926381 (MGI:1355063|PMID:10742104)
Ensembl
RGD
PMID:10742104 GO_REF:0000107, MGI:1355063 NCBI chr17:11,683,862...11,689,527
Ensembl chr17:11,683,862...11,689,527
JBrowse link
G Nectin1 nectin cell adhesion molecule 1 ISO MGI:3814719 (MGI:3814115|PMID:18703497) RGD PMID:18703497 MGI:3814115 NCBI chr 8:48,094,233...48,198,499
Ensembl chr 8:48,094,673...48,157,305
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha ISO MGI:1857774 (MGI:3843118|PMID:19320717) RGD PMID:19320717 MGI:3843118 NCBI chr 7:126,618,872...126,687,282
Ensembl chr 7:126,619,196...126,681,752
JBrowse link
G Stim1 stromal interaction molecule 1 ISO
ISS
(PMID:24621671)
GO_REF:0000024
RGD
UniProt
PMID:24621671 GO_REF:0000024 NCBI chr 1:167,373,894...167,533,412
Ensembl chr 1:167,373,678...167,533,420
JBrowse link
G Tbx1 T-box transcription factor 1 ISS
ISO
GO_REF:0000024
MGI:2179136 (MGI:3848106|PMID:19233155)
UniProt
RGD
PMID:19233155 GO_REF:0000024, MGI:3848106 NCBI chr11:86,552,022...86,561,647
Ensembl chr11:86,552,022...86,560,969
JBrowse link
G Tcirg1 T-cell immune regulator 1, ATPase H+ transporting V0 subunit A3 ISO MGI:1856973 (MGI:5469811|PMID:23174213) RGD PMID:23174213 MGI:5469811 NCBI chr 1:219,126,687...219,139,466
Ensembl chr 1:219,127,602...219,139,464
JBrowse link
G Wdr72 WD repeat domain 72 ISO MGI:4363147|MGI:5913851 (MGI:5605934|PMID:25008349), (MGI:5906533|PMID:26247047) RGD PMID:25008349, PMID:26247047 MGI:5605934, MGI:5906533 NCBI chr 8:80,965,734...81,125,710
Ensembl chr 8:80,965,255...81,039,246
JBrowse link
positive regulation of enamel mineralization term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Amtn amelotin ISS
ISO
IBA
GO_REF:0000024
(MGI:5613837|PMID:25407797)
PMID:21873635
UniProt
RGD
PMID:25407797, PMID:21873635 GO_REF:0000024, MGI:5613837, RGD:13792537 NCBI chr14:21,282,488...21,301,966
Ensembl chr14:21,286,510...21,299,068
JBrowse link
G Dspp dentin sialophosphoprotein ISO (MGI:3603472|PMID:16014627) RGD PMID:16014627 MGI:3603472 NCBI chr14:6,926,972...6,933,079
Ensembl chr14:6,926,976...6,933,070
JBrowse link
G Enam enamelin IBA
ISO
PMID:21873635
MGI:3796583 (MGI:5647983|PMID:24603688)
RGD PMID:24603688, PMID:21873635 MGI:5647983, RGD:13792537 NCBI chr14:21,194,635...21,219,529
Ensembl chr14:21,194,664...21,219,454
JBrowse link
G Odaph odontogenesis associated phosphoprotein ISO
IBA
ISS
(PMID:22901946)
PMID:21873635
GO_REF:0000024
RGD
UniProt
PMID:22901946, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr14:17,575,295...17,583,214
Ensembl chr14:17,575,758...17,582,823
JBrowse link
regulation of enamel mineralization term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dicer1 dicer 1 ribonuclease III ISO MGI:3589208 (MGI:4453947|PMID:20102707) RGD PMID:20102707 MGI:4453947 NCBI chr 6:128,388,084...128,453,234
Ensembl chr 6:128,388,053...128,434,183
JBrowse link
G Dmp1 dentin matrix acidic phosphoprotein 1 IEA
ISO
GO_REF:0000107
(MGI:3603472|PMID:16014627)
Ensembl
RGD
PMID:16014627 GO_REF:0000107, MGI:3603472 NCBI chr14:6,889,851...6,923,961
Ensembl chr14:6,889,856...6,900,733
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20020
    developmental process 6826
      anatomical structure formation involved in morphogenesis 1214
        amelogenesis 27
          enamel mineralization + 19
Path 2
Term Annotations click to browse term
  biological_process 20020
    developmental process 6826
      anatomical structure development 6268
        multicellular organism development 5743
          system development 5279
            animal organ development 4033
              animal organ morphogenesis 1151
                odontogenesis 150
                  odontogenesis of dentin-containing tooth 104
                    amelogenesis 27
                      enamel mineralization + 19
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.