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ONTOLOGY REPORT - ANNOTATIONS


Term:execution phase of apoptosis
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Accession:GO:0097194 term browser browse the term
Definition:A stage of the apoptotic process that starts with the controlled breakdown of the cell through the action of effector caspases or other effector molecules (e.g. cathepsins, calpains etc.). Key steps of the execution phase are rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.
Synonyms:exact_synonym: execution phase of apoptotic process
 narrow_synonym: apoptosis


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execution phase of apoptosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aifm3 apoptosis inducing factor, mitochondria associated 3 ISO (PMID:15764604) RGD PMID:15764604 NCBI chr11:87,364,452...87,380,705
Ensembl chr11:87,366,621...87,380,704
JBrowse link
G Akt1 AKT serine/threonine kinase 1 ISO (MGI:MGI:2387238|PMID:12124386) RGD PMID:12124386 MGI:MGI:2387238 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Bbc3 Bcl-2 binding component 3 ISO
IBA
(PMID:11463391), (PMID:11463392)
PMID:21873635
RGD PMID:11463391, PMID:11463392, PMID:21873635 RGD:13792537 NCBI chr 1:78,261,491...78,267,802 JBrowse link
G Casp1 caspase 1 IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 8:2,605,743...2,614,637
Ensembl chr 8:2,604,962...2,614,631
JBrowse link
G Casp12 caspase 12 IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 8:2,658,892...2,686,160
Ensembl chr 8:2,659,865...2,686,160
JBrowse link
G Casp14 caspase 14 IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 7:13,938,376...13,944,286
Ensembl chr 7:13,938,302...13,945,130
JBrowse link
G Casp2 caspase 2 IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 4:71,652,358...71,670,228
Ensembl chr 4:71,652,354...71,670,239
JBrowse link
G Casp3 caspase 3 ISO (PMID:11350920), (PMID:8689682)
MGI:MGI:109383|MGI:MGI:2651856 (MGI:MGI:2150278|PMID:11549719), (MGI:MGI:2387238|PMID:12124386), (MGI:MGI:2674166|PMID:12954857), (MGI:MGI:3056854|PMID:15456877), (MGI:MGI:3615714|PMID:16469926)
RGD PMID:8689682, PMID:11350920, PMID:11549719, PMID:12124386, PMID:12954857, PMID:15456877, PMID:16469926 MGI:MGI:2150278, MGI:MGI:2387238, MGI:MGI:2674166, MGI:MGI:3056854, MGI:MGI:3615714 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp4 caspase 4 IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 8:2,616,391...2,651,682
Ensembl chr 8:2,635,851...2,651,652
JBrowse link
G Casp6 caspase 6 IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 2:235,341,326...235,353,715
Ensembl chr 2:235,341,365...235,353,967
Ensembl chr 2:235,341,365...235,353,967
JBrowse link
G Casp7 caspase 7 ISO
IBA
MGI:MGI:107739 (MGI:MGI:3615714|PMID:16469926)
PMID:21873635
RGD PMID:16469926, PMID:21873635 MGI:MGI:3615714, RGD:13792537 NCBI chr 1:277,190,557...277,242,779
Ensembl chr 1:277,190,964...277,242,774
JBrowse link
G Casp8 caspase 8 ISO
ISS
(PMID:21737330)
(MGI:MGI:5602910|PMID:24813850), (MGI:MGI:5602911|PMID:24813849)
GO_REF:0000024
RGD
UniProt
PMID:21737330, PMID:24813849, PMID:24813850 GO_REF:0000024, MGI:MGI:5602910, MGI:MGI:5602911 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Casp9 caspase 9 IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Cecr2 CECR2, histone acetyl-lysine reader ISO (PMID:12762840) RGD PMID:12762840 NCBI chr 4:153,217,521...153,327,153
Ensembl chr 4:153,217,782...153,322,564
JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 9:65,534,608...65,586,395
Ensembl chr 9:65,534,704...65,587,251
JBrowse link
G Cideb cell death-inducing DFFA-like effector b ISO (MGI:MGI:1203887|PMID:9564035) RGD PMID:9564035 MGI:MGI:1203887 NCBI chr15:34,439,844...34,444,244
Ensembl chr15:34,439,876...34,444,244
JBrowse link
G Cidec cell death-inducing DFFA-like effector c ISO (PMID:12429024) RGD PMID:12429024 NCBI chr 4:145,377,482...145,390,497
Ensembl chr 4:145,377,431...145,390,497
JBrowse link
G LOC103689977 caspase-6 IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 2:230,186,170...230,198,555
Ensembl chr 2:230,186,198...230,198,555
JBrowse link
G Madd MAP-kinase activating death domain IEA
ISO
GO_REF:0000107
(MGI:MGI:3700423|PMID:14735464)
(PMID:14735464)
Ensembl
RGD
PMID:14735464 GO_REF:0000107, MGI:MGI:3700423 NCBI chr 3:79,960,301...80,003,023
Ensembl chr 3:79,960,301...80,003,032
JBrowse link
G Stk24 serine/threonine kinase 24 IEA
ISO
GO_REF:0000107
(PMID:12107159)
Ensembl
RGD
PMID:12107159 GO_REF:0000107 NCBI chr15:106,629,258...106,678,917
Ensembl chr15:106,629,312...106,678,918
JBrowse link
G Taok1 TAO kinase 1 IEA
IBA
ISS
ISO
GO_REF:0000107
PMID:21873635
GO_REF:0000024
(PMID:16407310)
Ensembl
UniProt
RGD
PMID:16407310, PMID:21873635 GO_REF:0000024, GO_REF:0000107, RGD:13792537 NCBI chr10:62,542,870...62,630,341
Ensembl chr10:62,566,732...62,630,155
JBrowse link
apoptotic chromosome condensation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acin1 apoptotic chromatin condensation inducer 1 ISO (PMID:10490026) RGD PMID:10490026 NCBI chr15:33,288,369...33,333,256
Ensembl chr15:33,288,374...33,333,417
JBrowse link
G Dffb DNA fragmentation factor subunit beta ISO (PMID:10959840) RGD PMID:10959840 NCBI chr 5:171,250,559...171,261,875
Ensembl chr 5:171,249,633...171,262,119
JBrowse link
G Ern2 endoplasmic reticulum to nucleus signaling 2 ISO (PMID:11175748) RGD PMID:11175748 NCBI chr 1:192,126,023...192,142,865
Ensembl chr 1:192,126,023...192,142,854
JBrowse link
G Gper1 G protein-coupled estrogen receptor 1 IDA PMID:23907461 UniProt PMID:23907461 RGD:8553942 NCBI chr12:17,309,122...17,315,267
Ensembl chr12:17,309,834...17,311,112
JBrowse link
G Top2a DNA topoisomerase II alpha IEA
IBA
ISO
GO_REF:0000107
PMID:21873635
(PMID:10959840)
Ensembl
RGD
PMID:10959840, PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr10:86,901,467...86,930,947
Ensembl chr10:86,901,007...86,932,154
JBrowse link
apoptotic DNA fragmentation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dffa DNA fragmentation factor subunit alpha IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 5:165,922,893...165,935,822
Ensembl chr 5:165,922,915...165,935,821
JBrowse link
G Dffb DNA fragmentation factor subunit beta IDA
IEA
IBA
ISO
GO_REF:0000002
PMID:21873635
(PMID:15572351), (PMID:22253444)
InterPro
RGD
PMID:15572351, PMID:22253444, PMID:11425895, PMID:21873635 GO_REF:0000002, RGD:628524, RGD:13792537 NCBI chr 5:171,250,559...171,261,875
Ensembl chr 5:171,249,633...171,262,119
JBrowse link
G Dicer1 dicer 1 ribonuclease III IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 6:128,388,084...128,453,234
Ensembl chr 6:128,388,053...128,434,183
JBrowse link
G Dnase1l3 deoxyribonuclease 1-like 3 TAS
IBA
ISO
PMID:21873635
(PMID:23229555)
(MGI:MGI:2385551|PMID:12050166)
RGD PMID:12050166, PMID:23229555, PMID:9665719, PMID:21873635 MGI:MGI:2385551, RGD:728743, RGD:13792537 NCBI chr15:18,710,492...18,736,476
Ensembl chr15:18,710,492...18,736,473
JBrowse link
G Dnase2 deoxyribonuclease 2, lysosomal IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr19:26,022,855...26,025,523
Ensembl chr19:26,022,849...26,025,532
JBrowse link
G Dnase2b deoxyribonuclease 2 beta IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:252,436,363...252,475,506
Ensembl chr 2:252,436,332...252,451,999
JBrowse link
G Endog endonuclease G ISO
IBA
MGI:MGI:3034030|MGI:MGI:3514265 (MGI:MGI:3029597|PMID:14663139)
PMID:21873635
RGD PMID:14663139, PMID:21873635 MGI:MGI:3029597, RGD:13792537 NCBI chr 3:8,741,833...8,744,414
Ensembl chr 3:8,741,766...8,744,592
JBrowse link
G Exog exo/endonuclease G IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:128,133,398...128,153,110
Ensembl chr 8:128,133,431...128,153,110
JBrowse link
G Foxl2 forkhead box L2 ISO (PMID:16153597) RGD PMID:16153597 NCBI chr 8:107,194,492...107,197,644
Ensembl chr 8:107,194,551...107,195,675
JBrowse link
apoptotic nuclear changes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr1c activin A receptor type 1C IEA
ISO
GO_REF:0000107
(PMID:15531507)
Ensembl
RGD
PMID:15531507 GO_REF:0000107 NCBI chr 3:44,272,859...44,342,501
Ensembl chr 3:44,270,653...44,342,355
JBrowse link
G Blcap BLCAP, apoptosis inducing factor ISO (PMID:17031575) RGD PMID:17031575 NCBI chr 3:154,040,165...154,042,096
Ensembl chr 3:154,040,166...154,042,099
JBrowse link
G Cd24 CD24 molecule ISO (MGI:MGI:2686748|PMID:14707049) RGD PMID:14707049 MGI:MGI:2686748 NCBI chr20:48,335,540...48,340,847
Ensembl chr20:48,335,540...48,340,846
JBrowse link
G Cdk5rap3 CDK5 regulatory subunit associated protein 3 IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:23478299)
Ensembl
UniProt
RGD
PMID:23478299 GO_REF:0000024, GO_REF:0000107 NCBI chr10:84,780,644...84,789,800
Ensembl chr10:84,780,608...84,789,832
JBrowse link
G Dedd2 death effector domain containing 2 ISO (PMID:11741985) RGD PMID:11741985 NCBI chr 1:82,073,024...82,089,028
Ensembl chr 1:82,072,544...82,088,275
JBrowse link
G Sharpin SHANK-associated RH domain interactor ISO MGI:MGI:1856699 (MGI:MGI:75289|PMID:7792947) RGD PMID:7792947 MGI:MGI:75289 NCBI chr 7:117,413,151...117,417,455
Ensembl chr 7:117,413,152...117,417,363
JBrowse link
cellular component disassembly involved in execution phase of apoptosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bok BCL2 family apoptosis regulator BOK ISO
ISS
(MGI:MGI:5705719|PMID:23429263)
GO_REF:0000024
RGD
UniProt
PMID:23429263 GO_REF:0000024, MGI:MGI:5705719 NCBI chr 9:100,829,593...100,840,498
Ensembl chr 9:100,829,552...100,840,504
JBrowse link
negative regulation of apoptotic DNA fragmentation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dffa DNA fragmentation factor subunit alpha ISO (PMID:15572351)
MGI:MGI:2179456 (MGI:MGI:2182584|PMID:10601318), (MGI:MGI:3029597|PMID:14663139)
RGD PMID:10601318, PMID:14663139, PMID:15572351 MGI:MGI:2182584, MGI:MGI:3029597 NCBI chr 5:165,922,893...165,935,822
Ensembl chr 5:165,922,915...165,935,821
JBrowse link
G Nmnat1 nicotinamide nucleotide adenylyltransferase 1 IMP RGD PMID:27184051 RGD:13781945 NCBI chr 5:166,409,460...166,430,291
Ensembl chr 5:166,409,461...166,430,254
JBrowse link
G Pam16 presequence translocase associated motor 16 IDA RGD PMID:24069394 RGD:13462066 NCBI chr10:11,146,359...11,153,936
Ensembl chr10:11,146,359...11,153,936
JBrowse link
negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pak2 p21 (RAC1) activated kinase 2 ISO (PMID:21555521) RGD PMID:21555521 NCBI chr11:72,829,407...72,865,815
Ensembl chr11:72,829,238...72,865,902
JBrowse link
G Rffl ring finger and FYVE-like domain containing E3 ubiquitin protein ligase ISO
IBA
ISS
(PMID:15069192)
PMID:21873635
GO_REF:0000024
RGD
UniProt
PMID:15069192, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr10:70,157,621...70,220,618
Ensembl chr10:70,157,621...70,220,582
JBrowse link
G Rnf34 ring finger protein 34 ISO
IBA
ISS
(PMID:15069192)
PMID:21873635
GO_REF:0000024
RGD
UniProt
PMID:15069192, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr12:39,164,290...39,185,209
Ensembl chr12:39,164,290...39,185,168
JBrowse link
negative regulation of execution phase of apoptosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl2l1 Bcl2-like 1 ISO
ISS
(PMID:20673843)
GO_REF:0000024
RGD
UniProt
PMID:20673843 GO_REF:0000024 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810
JBrowse link
G Cidea cell death-inducing DFFA-like effector a ISO (MGI:MGI:3768618|PMID:17080483) RGD PMID:17080483 MGI:MGI:3768618 NCBI chr18:63,082,861...63,108,450
Ensembl chr18:63,098,144...63,108,051
JBrowse link
G Cxcr3 C-X-C motif chemokine receptor 3 ISO
ISS
(PMID:12782716)
GO_REF:0000024
RGD
UniProt
PMID:12782716 GO_REF:0000024 NCBI chr  X:71,614,346...71,616,997
Ensembl chr  X:71,614,346...71,616,997
JBrowse link
G Dffa DNA fragmentation factor subunit alpha ISO
IBA
(PMID:9564035)
PMID:21873635
RGD PMID:9564035, PMID:21873635 RGD:13792537 NCBI chr 5:165,922,893...165,935,822
Ensembl chr 5:165,922,915...165,935,821
JBrowse link
G Fzd3 frizzled class receptor 3 ISO (MGI:MGI:4941059|PMID:21325504) RGD PMID:21325504 MGI:MGI:4941059 NCBI chr15:48,601,259...48,670,257
Ensembl chr15:48,601,266...48,670,257
JBrowse link
G Gcg glucagon ISO
IEA
(MGI:MGI:4453294|PMID:19915011)
GO_REF:0000107
RGD
Ensembl
PMID:19915011 GO_REF:0000107, MGI:MGI:4453294 NCBI chr 3:48,442,635...48,451,650
Ensembl chr 3:48,442,635...48,451,650
JBrowse link
nuclear fragmentation involved in apoptotic nuclear change term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gper1 G protein-coupled estrogen receptor 1 IDA PMID:23907461 UniProt PMID:23907461 RGD:8553942 NCBI chr12:17,309,122...17,315,267
Ensembl chr12:17,309,834...17,311,112
JBrowse link
phosphatidylserine exposure on apoptotic cell surface term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ano6 anoctamin 6 NOT ISO MGI:MGI:4127698 (MGI:MGI:5486117|PMID:22936354), (MGI:MGI:5496475|PMID:23532839) RGD PMID:22936354, PMID:23532839 MGI:MGI:5486117, MGI:MGI:5496475 NCBI chr 7:137,142,063...137,335,208
Ensembl chr 7:137,142,170...137,335,208
JBrowse link
G Plscr1 phospholipid scramblase 1 IEA
ISO
ISS
IBA
GO_REF:0000107
(MGI:MGI:5284813|PMID:12509439), (MGI:MGI:6450314|PMID:32110987)
GO_REF:0000024
(PMID:32110987)
PMID:21873635
Ensembl
RGD
UniProt
PMID:12509439, PMID:32110987, PMID:21873635 GO_REF:0000024, GO_REF:0000107, MGI:MGI:5284813, MGI:MGI:6450314, RGD:13792537 NCBI chr 8:99,625,523...99,645,882
Ensembl chr 8:99,625,545...99,725,217
JBrowse link
G Trpc5 transient receptor potential cation channel, subfamily C, member 5 ISO (MGI:MGI:6450314|PMID:32110987) RGD PMID:32110987 MGI:MGI:6450314 NCBI chr  X:115,624,670...115,908,248
Ensembl chr  X:115,627,653...115,908,693
JBrowse link
G Xkr4 XK related 4 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:15,746,012...16,141,059
Ensembl chr 5:15,747,614...16,140,896
JBrowse link
G Xkr5 XK related 5 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:75,744,786...75,762,694
Ensembl chr16:75,744,786...75,762,693
JBrowse link
G Xkr6 XK related 6 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr15:46,784,963...47,173,352
Ensembl chr15:46,784,963...47,173,335
JBrowse link
G Xkr7 XK related 7 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:148,508,622...148,537,904
Ensembl chr 3:148,510,779...148,533,404
JBrowse link
G Xkr8 XK related 8 ISO
IBA
(PMID:23845944)
MGI:MGI:5528895 (MGI:MGI:5502792|PMID:23845944), (MGI:MGI:6120635|PMID:29440417)
PMID:21873635
RGD PMID:23845944, PMID:29440417, PMID:21873635 MGI:MGI:5502792, MGI:MGI:6120635, RGD:13792537 NCBI chr 5:150,918,600...150,925,727
Ensembl chr 5:150,918,603...150,925,727
JBrowse link
G Xkr9 XK related 9 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:4,946,332...4,975,436
Ensembl chr 5:4,946,006...4,975,436
JBrowse link
positive regulation of apoptotic DNA fragmentation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator ISO
IEA
(PMID:11350920)
GO_REF:0000107
RGD
Ensembl
PMID:11350920 GO_REF:0000107 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Endog endonuclease G IMP RGD PMID:16407272 RGD:9685355 NCBI chr 3:8,741,833...8,744,414
Ensembl chr 3:8,741,766...8,744,592
JBrowse link
G Hsf1 heat shock transcription factor 1 IMP RGD PMID:21192280 RGD:10403035 NCBI chr 7:117,538,523...117,565,478
Ensembl chr 7:117,538,523...117,565,478
JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 IMP RGD PMID:15125883 RGD:10402776 NCBI chr14:87,457,647...87,465,374
Ensembl chr14:87,457,647...87,465,374
JBrowse link
G Il6 interleukin 6 ISO (PMID:28433754) RGD PMID:28433754 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rps3 ribosomal protein S3 ISO (PMID:22510408) RGD PMID:22510408 NCBI chr 1:164,435,868...164,441,167
Ensembl chr 1:164,435,878...164,441,167
JBrowse link
G Tnf tumor necrosis factor IMP RGD PMID:12131680 RGD:14995454 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
positive regulation of execution phase of apoptosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bok BCL2 family apoptosis regulator BOK ISO
ISS
(PMID:20673843)
GO_REF:0000024
RGD
UniProt
PMID:20673843 GO_REF:0000024 NCBI chr 9:100,829,593...100,840,498
Ensembl chr 9:100,829,552...100,840,504
JBrowse link
G Cxcr3 C-X-C motif chemokine receptor 3 ISO (PMID:12782716) RGD PMID:12782716 NCBI chr  X:71,614,346...71,616,997
Ensembl chr  X:71,614,346...71,616,997
JBrowse link
G Dlc1 DLC1 Rho GTPase activating protein IEA
ISO
GO_REF:0000107
(PMID:17888903)
Ensembl
RGD
PMID:17888903 GO_REF:0000107 NCBI chr16:58,776,489...59,247,752
Ensembl chr16:59,077,574...59,247,754
JBrowse link
G Fap fibroblast activation protein, alpha ISO (MGI:MGI:3047166|PMID:15133496) RGD PMID:15133496 MGI:MGI:3047166 NCBI chr 3:48,467,781...48,536,242
Ensembl chr 3:48,467,781...48,536,235
JBrowse link
G Ptgis prostaglandin I2 synthase ISO
ISS
(PMID:11551955)
GO_REF:0000024
RGD
UniProt
PMID:11551955 GO_REF:0000024 NCBI chr 3:163,950,746...163,986,129 JBrowse link
G Sirt2 sirtuin 2 IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(MGI:MGI:5572869|PMID:17521387)
Ensembl
UniProt
RGD
PMID:17521387 GO_REF:0000024, GO_REF:0000107, MGI:MGI:5572869 NCBI chr 1:86,948,866...86,971,954
Ensembl chr 1:86,948,918...86,971,952
JBrowse link
G Tp53 tumor protein p53 ISO (PMID:14985081) RGD PMID:14985081 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Tp53bp2 tumor protein p53 binding protein, 2 ISO (PMID:14985081) RGD PMID:14985081 NCBI chr13:100,817,206...100,873,837
Ensembl chr13:100,817,359...100,873,890
JBrowse link
G Zc3h12a zinc finger CCCH type containing 12A ISO (MGI:MGI:5297619|PMID:21971051) RGD PMID:21971051 MGI:MGI:5297619 NCBI chr 5:143,111,342...143,120,131
Ensembl chr 5:143,111,074...143,120,165
JBrowse link
regulation of apoptotic DNA fragmentation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aifm1 apoptosis inducing factor, mitochondria associated 1 ISO MGI:MGI:1306796 (MGI:MGI:3577148|PMID:15703386) RGD PMID:15703386 MGI:MGI:3577148 NCBI chr  X:135,304,063...135,343,062
Ensembl chr  X:135,304,066...135,343,087
JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 ISO MGI:MGI:1349414 (MGI:MGI:3577148|PMID:15703386) RGD PMID:15703386 MGI:MGI:3577148 NCBI chr 7:31,699,309...31,784,192
Ensembl chr 7:31,699,885...31,784,192
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A ISO (PMID:12082630) RGD PMID:12082630 NCBI chr 5:107,823,323...107,832,405
Ensembl chr 5:107,823,330...107,841,175
JBrowse link
G Cidea cell death-inducing DFFA-like effector a ISO (MGI:MGI:1203887|PMID:9564035) RGD PMID:9564035 MGI:MGI:1203887 NCBI chr18:63,082,861...63,108,450
Ensembl chr18:63,098,144...63,108,051
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20014
    cellular process 18788
      execution phase of apoptosis 76
        cellular component disassembly involved in execution phase of apoptosis + 30
        negative regulation of execution phase of apoptosis + 11
        phosphatidylserine exposure on apoptotic cell surface + 9
        positive regulation of execution phase of apoptosis + 16
        regulation of execution phase of apoptosis + 29
Path 2
Term Annotations click to browse term
  biological_process 20014
    cellular process 18788
      cell death 2154
        programmed cell death 1968
          apoptotic process 1922
            execution phase of apoptosis 76
              cellular component disassembly involved in execution phase of apoptosis + 30
              negative regulation of execution phase of apoptosis + 11
              phosphatidylserine exposure on apoptotic cell surface + 9
              positive regulation of execution phase of apoptosis + 16
              regulation of execution phase of apoptosis + 29
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.