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ONTOLOGY REPORT - ANNOTATIONS


Term:histone H3-K36 trimethylation
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Accession:GO:0097198 term browser browse the term
Definition:The modification of histone H3 by addition of three methyl groups to lysine at position 36 of the histone.


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histone H3-K36 trimethylation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prdm9 PR/SET domain 9 ISS
ISO
GO_REF:0000024
(MGI:MGI:5784565|PMID:27362481)
UniProt
RGD
PMID:27362481 GO_REF:0000024, MGI:MGI:5784565 NCBI chr 1:57,533,602...57,555,155
Ensembl chr 1:57,533,577...57,555,048
JBrowse link
G Setd2 SET domain containing 2, histone lysine methyltransferase ISO (PMID:19141475), (PMID:23043551), (PMID:23325844), (PMID:23622243), (PMID:24843002), (PMID:26002201), (PMID:27474439), (PMID:28753426)
(MGI:MGI:5528755|PMID:24036311), (MGI:MGI:5908786|PMID:25242323)
RGD PMID:19141475, PMID:23043551, PMID:23325844, PMID:23622243, PMID:24036311, PMID:24843002, PMID:25242323, PMID:26002201, PMID:27474439, PMID:28753426 MGI:MGI:5528755, MGI:MGI:5908786 NCBI chr 8:118,802,478...118,888,224
Ensembl chr 8:118,803,075...118,888,224
JBrowse link
G Setd5 SET domain containing 5 ISO (MGI:MGI:6381850|PMID:31515109) RGD PMID:31515109 MGI:MGI:6381850 NCBI chr 4:145,017,549...145,095,247
Ensembl chr 4:145,017,608...145,095,245
JBrowse link
positive regulation of histone H3-K36 trimethylation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Brd4 bromodomain containing 4 ISO (PMID:21555454) RGD PMID:21555454 NCBI chr 7:14,222,101...14,303,055
Ensembl chr 7:14,222,101...14,303,055
JBrowse link
G Nsd3 nuclear receptor binding SET domain protein 3 ISO (PMID:21555454) RGD PMID:21555454 NCBI chr16:71,126,276...71,237,118
Ensembl chr16:71,130,668...71,237,118
JBrowse link
G Prdm9 PR/SET domain 9 ISO
ISS
(PMID:24634223)
GO_REF:0000024
RGD
UniProt
PMID:24634223 GO_REF:0000024 NCBI chr 1:57,533,602...57,555,155
Ensembl chr 1:57,533,577...57,555,048
JBrowse link
regulation of histone H3-K36 trimethylation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Iws1 interacts with SUPT6H, CTD assembly factor 1 IEA
IBA
ISO
ISS
GO_REF:0000107
PMID:21873635
(PMID:19141475)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:19141475, PMID:21873635 GO_REF:0000024, GO_REF:0000107, RGD:13792537 NCBI chr18:24,849,508...24,891,339
Ensembl chr18:24,849,545...24,880,317
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20014
    metabolic process 12256
      methylation 369
        macromolecule methylation 334
          protein methylation 204
            peptidyl-lysine methylation 143
              peptidyl-lysine trimethylation 55
                histone H3-K36 trimethylation 6
                  negative regulation of histone H3-K36 trimethylation 0
                  positive regulation of histone H3-K36 trimethylation 3
                  regulation of histone H3-K36 trimethylation + 4
Path 2
Term Annotations click to browse term
  biological_process 20014
    metabolic process 12256
      organic substance metabolic process 11636
        organonitrogen compound metabolic process 7132
          protein metabolic process 6214
            cellular protein metabolic process 5552
              cellular protein modification process 3937
                protein alkylation 204
                  protein methylation 204
                    histone methylation 159
                      histone lysine methylation 128
                        histone H3-K36 methylation 16
                          histone H3-K36 trimethylation 6
                            negative regulation of histone H3-K36 trimethylation 0
                            positive regulation of histone H3-K36 trimethylation 3
                            regulation of histone H3-K36 trimethylation + 4
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.