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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of transcription from RNA polymerase II promoter in response to stress
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Accession:GO:0097201 term browser browse the term
Definition:Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).


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negative regulation of transcription from RNA polymerase II promoter in response to stress term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bag3 BAG cochaperone 3 ISO (PMID:26159920) RGD PMID:26159920 NCBI chr 1:199,941,258...199,965,191
Ensembl chr 1:199,941,161...199,965,191
JBrowse link
G Dnajb1 DnaJ heat shock protein family (Hsp40) member B1 ISO (PMID:9499401) RGD PMID:9499401 NCBI chr19:24,747,178...24,750,919
Ensembl chr19:24,747,178...24,750,919
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A ISO
ISS
(PMID:9499401)
GO_REF:0000024
RGD
UniProt
PMID:9499401 GO_REF:0000024 NCBI chr20:4,875,834...4,881,751
Ensembl chr20:4,877,324...4,879,779
JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B ISO
ISS
(PMID:9499401)
GO_REF:0000024
RGD
UniProt
PMID:9499401 GO_REF:0000024 NCBI chr20:4,877,638...4,880,112
Ensembl chr20:2,699,712...2,701,815
JBrowse link
G Impact impact RWD domain protein ISO
ISS
(MGI:MGI:5576818|PMID:24333428)
GO_REF:0000024
RGD
UniProt
PMID:24333428 GO_REF:0000024, MGI:MGI:5576818 NCBI chr18:4,325,872...4,346,734
Ensembl chr18:4,325,875...4,346,769
JBrowse link
G LOC108348108 heat shock 70 kDa protein 1A ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr20:2,699,707...2,701,856
Ensembl chr20:4,877,324...4,879,779
Ensembl chr20:4,877,324...4,879,779
JBrowse link
G Nfe2l1 nuclear factor, erythroid 2-like 1 ISO (MGI:MGI:6101031|PMID:29149604) RGD PMID:29149604 MGI:MGI:6101031 NCBI chr10:84,686,762...84,699,313
Ensembl chr10:84,682,460...84,698,886
JBrowse link
negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Jun Jun proto-oncogene, AP-1 transcription factor subunit ISO (PMID:21113145) RGD PMID:21113145 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
JBrowse link
G Nck1 NCK adaptor protein 1 ISO (PMID:16835242)
UniProtKB:O55033 (MGI:MGI:5613475|PMID:16835242)
RGD PMID:16835242 MGI:MGI:5613475 NCBI chr 8:108,787,797...108,847,779
Ensembl chr 8:108,787,798...108,847,779
JBrowse link
G Nck2 NCK adaptor protein 2 ISO UniProtKB:Q99M51 (MGI:MGI:5613475|PMID:16835242) RGD PMID:16835242 MGI:MGI:5613475 NCBI chr 9:50,246,767...50,373,307
Ensembl chr 9:50,247,692...50,373,284
JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A ISO (MGI:MGI:5605960|PMID:11381086) RGD PMID:11381086 MGI:MGI:5605960 NCBI chr 1:101,511,899...101,515,043
Ensembl chr 1:101,511,901...101,514,974
JBrowse link
G Tmbim6 transmembrane BAX inhibitor motif containing 6 ISO (MGI:MGI:3840374|PMID:19328063) RGD PMID:19328063 MGI:MGI:3840374 NCBI chr 7:141,039,433...141,070,269
Ensembl chr 7:141,034,982...141,069,989
JBrowse link
negative regulation of transcription from RNA polymerase II promoter in response to hypoxia term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 ISO (PMID:22735262) RGD PMID:22735262 NCBI chr 1:12,823,363...12,825,806
Ensembl chr 1:12,823,363...12,825,786
JBrowse link
G Hif1an hypoxia inducible factor 1 subunit alpha inhibitor ISO
IBA
(PMID:11641274)
PMID:21873635
RGD PMID:11641274, PMID:21873635 RGD:13792537 NCBI chr 1:264,309,214...264,319,269
Ensembl chr 1:264,309,214...264,319,267
JBrowse link
G Sirt2 sirtuin 2 IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:24681946)
Ensembl
UniProt
RGD
PMID:24681946 GO_REF:0000024, GO_REF:0000107 NCBI chr 1:86,948,866...86,971,954
Ensembl chr 1:86,948,918...86,971,952
JBrowse link
G Vhl von Hippel-Lindau tumor suppressor ISO (PMID:11641274) RGD PMID:11641274 NCBI chr 4:145,580,869...145,587,835
Ensembl chr 4:145,580,799...145,587,845
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20027
    response to stimulus 10583
      response to stress 4061
        cellular response to stress 1982
          regulation of DNA-templated transcription in response to stress 55
            regulation of transcription from RNA polymerase II promoter in response to stress 51
              negative regulation of transcription from RNA polymerase II promoter in response to stress 16
                negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress 5
                negative regulation of transcription from RNA polymerase II promoter in response to hypoxia 4
                negative regulation of transcription from RNA polymerase II promoter in response to iron ion starvation 0
                negative regulation of transcription from RNA polymerase II promoter in response to oxidative stress 0
Path 2
Term Annotations click to browse term
  biological_process 20027
    metabolic process 12278
      cellular metabolic process 11085
        cellular aromatic compound metabolic process 5715
          nucleobase-containing compound metabolic process 5489
            nucleic acid metabolic process 4985
              RNA metabolic process 4469
                RNA biosynthetic process 3477
                  nucleic acid-templated transcription 3463
                    regulation of nucleic acid-templated transcription 3336
                      regulation of transcription, DNA-templated 3287
                        regulation of transcription by RNA polymerase II 2417
                          regulation of transcription from RNA polymerase II promoter in response to stress 51
                            negative regulation of transcription from RNA polymerase II promoter in response to stress 16
                              negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress 5
                              negative regulation of transcription from RNA polymerase II promoter in response to hypoxia 4
                              negative regulation of transcription from RNA polymerase II promoter in response to iron ion starvation 0
                              negative regulation of transcription from RNA polymerase II promoter in response to oxidative stress 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.