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ONTOLOGY REPORT - ANNOTATIONS


Term:activation of cysteine-type endopeptidase activity
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Accession:GO:0097202 term browser browse the term
Definition:Any process that initiates the activity of the inactive enzyme cysteine-type endopeptidase.
Comment:This term should be used to annotate gene products within the context of cellular processes other than apoptotic cell death (e.g., cell cycle arrest). To annotate gene products involved in activation of cysteine-type endopeptidases where the activation results in apoptotic process, please use the more granular term GO:0006919.
Synonyms:narrow_synonym: activation of caspase activity
 related_synonym: activation of metacaspase activity


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activation of cysteine-type endopeptidase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Asph aspartate-beta-hydroxylase JBrowse link 5 22,577,680 22,799,333 RGD:1624291
G Bad BCL2-associated agonist of cell death JBrowse link 1 222,198,516 222,207,459 RGD:1624291
RGD:13792537
G Bak1 BCL2-antagonist/killer 1 JBrowse link 20 5,609,620 5,618,899 RGD:1624291
RGD:1600115
G Casp8 caspase 8 JBrowse link 9 65,614,142 65,662,624 RGD:1624291
RGD:1600115
G Cideb cell death-inducing DFFA-like effector b JBrowse link 15 34,439,844 34,444,244 RGD:1624291
RGD:1600115
G Cyfip2 cytoplasmic FMR1 interacting protein 2 JBrowse link 10 31,278,746 31,419,235 RGD:1624291
RGD:13792537
G Fadd Fas associated via death domain JBrowse link 1 217,746,176 217,748,581 RGD:1624291
RGD:1600115
G Lgmn legumain JBrowse link 6 126,282,246 126,308,207 RGD:1600115
RGD:1624291
G Pawr pro-apoptotic WT1 regulator JBrowse link 7 51,273,764 51,353,700 RGD:9835366
G Perp PERP, TP53 apoptosis effector JBrowse link 1 14,224,392 14,236,838 RGD:1624291
RGD:1600115
G Pycard PYD and CARD domain containing JBrowse link 1 199,438,029 199,439,062 RGD:1624291
RGD:1600115
G Ripk2 receptor-interacting serine-threonine kinase 2 JBrowse link 5 29,838,713 29,870,390 RGD:1624291
RGD:1600115
G Tbc1d10a TBC1 domain family, member 10a JBrowse link 14 84,417,320 84,445,034 RGD:1624291
RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18166
    metabolic process 10845
      primary metabolic process 9754
        protein metabolic process 5590
          proteolysis 1772
            protein processing 226
              zymogen activation 64
                activation of cysteine-type endopeptidase activity 13
Path 2
Term Annotations click to browse term
  biological_process 18166
    metabolic process 10845
      organic substance metabolic process 10283
        macromolecule metabolic process 8818
          protein metabolic process 5590
            cellular protein metabolic process 4932
              regulation of cellular protein metabolic process 2658
                positive regulation of cellular protein metabolic process 1620
                  positive regulation of proteolysis 357
                    positive regulation of peptidase activity 185
                      positive regulation of endopeptidase activity 168
                        positive regulation of cysteine-type endopeptidase activity 147
                          activation of cysteine-type endopeptidase activity 13
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.