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ONTOLOGY REPORT - ANNOTATIONS


Term:complement-dependent cytotoxicity
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Accession:GO:0097278 term browser browse the term
Definition:Lysis of a cell resulting from triggering of the complement cascade. An example can be seen with complement activation and subsequent lysis of a bacterial cell as a result of the binding of IgM to the cell surface followed by the binding of complement proteins to that antibody.


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complement-dependent cytotoxicity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Rab27a RAB27A, member RAS oncogene family JBrowse link 8 79,722,334 79,776,228 RGD:1624291
RGD:1600115
negative regulation of complement-dependent cytotoxicity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd59 CD59 molecule JBrowse link 3 94,010,481 94,028,660 RGD:13792592
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 JBrowse link 9 17,817,791 17,823,163 RGD:10448271
G Il13 interleukin 13 JBrowse link 10 38,982,909 38,985,466 RGD:1624291
RGD:1600115
G Il4 interleukin 4 JBrowse link 10 38,963,979 38,969,531 RGD:1624291
G Jak3 Janus kinase 3 JBrowse link 16 20,107,471 20,120,678 RGD:1624291
G Stat6 signal transducer and activator of transcription 6 JBrowse link 7 70,946,228 70,963,542 RGD:1624291
positive regulation of complement-dependent cytotoxicity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Foxo1 forkhead box O1 JBrowse link 2 141,451,234 141,527,016 RGD:1624291
regulation of complement-dependent cytotoxicity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cdh5 cadherin 5 JBrowse link 19 1,025,122 1,074,333 RGD:1624291
G Il10 interleukin 10 JBrowse link 13 47,738,933 47,743,392 RGD:1624291
G Il11 interleukin 11 JBrowse link 1 72,636,959 72,643,255 RGD:1624291
G Tgfb2 transforming growth factor, beta 2 JBrowse link 13 105,039,639 105,142,010 RGD:1624291

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Term Annotations click to browse term
  biological_process 17883
    cell killing 184
      complement-dependent cytotoxicity 12
        negative regulation of complement-dependent cytotoxicity 6
        positive regulation of complement-dependent cytotoxicity 1
        regulation of complement-dependent cytotoxicity + 11
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