ONTOLOGY REPORT - ANNOTATIONS


Term:synaptic vesicle lumen acidification
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Accession:GO:0097401 term browser browse the term
Definition:The acidification of the synaptic vesicle lumen via transport of protons into the vesicle. The resulting electrochemical gradient powers neurotransmitter loading.
Synonyms:exact_synonym: synaptic vesicle lumen pH reduction;   synaptic vesicle proton loading


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synaptic vesicle lumen acidification term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atp6v1b1 ATPase H+ transporting V1 subunit B1 JBrowse link 4 115,417,100 115,435,754 RGD:1600115
G Clcn3 chloride voltage-gated channel 3 JBrowse link 16 32,448,821 32,520,649 RGD:1624291
RGD:13792537
G Slc17a7 solute carrier family 17 member 7 JBrowse link 1 101,161,265 101,172,292 RGD:1624291
RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17926
    developmental process 6339
      developmental maturation 321
        synaptic vesicle maturation 12
          synaptic vesicle lumen acidification 3
            negative regulation of synaptic vesicle lumen acidification 0
            positive regulation of synaptic vesicle lumen acidification 0
            regulation of synaptic vesicle lumen acidification + 0
Path 2
Term Annotations click to browse term
  biological_process 17926
    localization 5991
      establishment of localization 4600
        transport 4460
          ion transport 1732
            ion transmembrane transport 1163
              inorganic ion transmembrane transport 878
                inorganic cation transmembrane transport 752
                  proton transmembrane transport 157
                    synaptic vesicle lumen acidification 3
                      negative regulation of synaptic vesicle lumen acidification 0
                      positive regulation of synaptic vesicle lumen acidification 0
                      regulation of synaptic vesicle lumen acidification + 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.