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ONTOLOGY REPORT - ANNOTATIONS


Term:programmed cell death in response to reactive oxygen species
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Accession:GO:0097468 term browser browse the term
Definition:Cell death resulting from activation of endogenous cellular processes and occurring as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals.
Synonyms:exact_synonym: PCD in response to reactive oxygen species;   reactive oxygen species-mediated PCD;   reactive oxygen species-mediated programmed cell death
 broad_synonym: PCD in response to oxidative stress;   programmed cell death in response to oxidative stress


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programmed cell death in response to reactive oxygen species term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pjvk pejvakin ISO (MGI:MGI:6294584|PMID:30936319) RGD PMID:30936319 MGI:MGI:6294584 NCBI chr 3:63,508,386...63,518,163
Ensembl chr 3:63,510,293...63,518,147
JBrowse link
intrinsic apoptotic signaling pathway in response to hydrogen peroxide term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pdcd10 programmed cell death 10 ISO UniProtKB:O00506 (PMID:22652780) RGD PMID:22652780 NCBI chr 2:173,966,701...174,012,730
Ensembl chr 2:173,967,080...174,012,676
JBrowse link
G Stk25 serine/threonine kinase 25 ISO UniProtKB:Q9BUL8 (PMID:22652780) RGD PMID:22652780 NCBI chr 9:100,767,578...100,779,715
Ensembl chr 9:100,767,579...100,779,715
JBrowse link
negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Park7 Parkinsonism associated deglycase ISO
IEA
UniProtKB:Q99LX0 (PMID:14652021)
GO_REF:0000107
(MGI:MGI:5613479|PMID:14652021)
RGD
Ensembl
PMID:14652021 GO_REF:0000107, MGI:MGI:5613479 NCBI chr 5:167,982,438...168,004,724
Ensembl chr 5:167,982,439...168,004,724
JBrowse link
G Pink1 PTEN induced kinase 1 ISO (PMID:21177249), (PMID:23261939) RGD PMID:21177249, PMID:23261939 NCBI chr 5:156,677,146...156,689,258
Ensembl chr 5:156,677,146...156,689,415
JBrowse link
negative regulation of hydrogen peroxide-mediated programmed cell death term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Glrx glutaredoxin IMP RGD PMID:19938943 RGD:9686063 NCBI chr 2:2,606,032...2,615,944
Ensembl chr 2:2,605,996...2,615,944
JBrowse link
G Hgf hepatocyte growth factor ISO (PMID:20655899) RGD PMID:20655899 NCBI chr 4:15,435,460...15,505,377
Ensembl chr 4:15,433,295...15,505,362
JBrowse link
G Hk3 hexokinase 3 IDA PMID:21072205 CACAO PMID:21072205 RGD:10047370 NCBI chr17:10,134,726...10,152,976
Ensembl chr17:10,137,974...10,152,956
JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase ISO
IEA
(PMID:20655899)
GO_REF:0000107
RGD
Ensembl
PMID:20655899 GO_REF:0000107 NCBI chr 4:44,747,467...44,854,628
Ensembl chr 4:44,774,741...44,852,665
JBrowse link
negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hsph1 heat shock protein family H (Hsp110) member 1 ISO (MGI:MGI:3822965|PMID:18681888) RGD PMID:18681888 MGI:MGI:3822965 NCBI chr12:6,322,685...6,341,898
Ensembl chr12:6,322,668...6,341,902
JBrowse link
G Pink1 PTEN induced kinase 1 IMP
ISO
PMID:17579517
(PMID:17579517)
RGD PMID:17579517, PMID:17579517 RGD:8693356 NCBI chr 5:156,677,146...156,689,258
Ensembl chr 5:156,677,146...156,689,415
JBrowse link
G Trap1 TNF receptor-associated protein 1 IMP PMID:17579517 ParkinsonsUK-UCL PMID:17579517 RGD:8693356 NCBI chr10:11,724,032...11,757,682
Ensembl chr10:11,724,032...11,757,681
JBrowse link
positive regulation of hydrogen peroxide-mediated programmed cell death term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase IMP RGD PMID:21715626 RGD:8693407 NCBI chr 3:10,041,820...10,145,076
Ensembl chr 3:10,041,826...10,144,388
JBrowse link
G Endog endonuclease G IMP RGD PMID:20594982 RGD:9685387 NCBI chr 3:8,741,833...8,744,414
Ensembl chr 3:8,741,766...8,744,592
JBrowse link
G Foxo3 forkhead box O3 IMP RGD PMID:23585551 RGD:7327146 NCBI chr20:46,428,078...46,519,156
Ensembl chr20:46,428,124...46,519,144
JBrowse link
G Hdac6 histone deacetylase 6 ISO (PMID:18606987) RGD PMID:18606987 NCBI chr  X:15,295,372...15,316,673
Ensembl chr  X:15,295,473...15,316,671
JBrowse link
G Pawr pro-apoptotic WT1 regulator ISO
IEA
(MGI:MGI:5648604|PMID:25472717)
GO_REF:0000107
RGD
Ensembl
PMID:25472717 GO_REF:0000107, MGI:MGI:5648604 NCBI chr 7:51,273,764...51,353,700
Ensembl chr 7:51,273,771...51,353,068
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20028
    cellular process 18800
      cell death 2137
        cell death in response to oxidative stress 106
          programmed cell death in response to reactive oxygen species 16
            hydrogen peroxide-mediated programmed cell death + 15
            singlet oxygen-mediated programmed cell death 0
Path 2
Term Annotations click to browse term
  biological_process 20028
    response to stimulus 10583
      cellular response to stimulus 8919
        cellular response to stress 1981
          cellular response to chemical stress 418
            cellular response to oxidative stress 347
              cell death in response to oxidative stress 106
                programmed cell death in response to reactive oxygen species 16
                  hydrogen peroxide-mediated programmed cell death + 15
                  singlet oxygen-mediated programmed cell death 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.