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ONTOLOGY REPORT - ANNOTATIONS


Term:calcitonin family receptor signaling pathway
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Accession:GO:0097646 term browser browse the term
Definition:A series of molecular signals initiated by an extracellular member of the calcitonin family (e.g. adrenomedullin, adrenomedullin 2 (intermedin), amylin, calcitonin and calcitonin gene-related peptides (CGRPs)) combining with a calcitonin family receptor on the surface of the target cell. Calcitonin family receptors may form dimers, trimers or tetramers; adrenomedullin and amylin receptors have only been observed as dimers so far.
Synonyms:exact_synonym: calcitonin family receptor signalling pathway


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adrenomedullin receptor signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adm adrenomedullin ISO (PMID:10882736), (PMID:18434369), (PMID:20074556) RGD PMID:10882736, PMID:18434369, PMID:20074556 NCBI chr 1:175,443,189...175,447,260
Ensembl chr 1:175,445,088...175,447,259
JBrowse link
G Calcrl calcitonin receptor like receptor ISO UniProtKB:O60895|UniProtKB:O60896 (PMID:10882736), (PMID:20074556), (PMID:22102369), (PMID:9620797)
UniProtKB:Q7YS88|UniProtKB:Q867B9 (PMID:18434369)
RGD PMID:9620797, PMID:10882736, PMID:18434369, PMID:20074556, PMID:22102369 NCBI chr 3:71,747,938...71,845,487
Ensembl chr 3:71,747,956...71,845,232
JBrowse link
G Ramp2 receptor activity modifying protein 2 ISO UniProtKB:Q16602 (PMID:10882736), (PMID:20074556), (PMID:22102369), (PMID:9620797)
UniProtKB:Q8WN93 (PMID:18434369)
RGD PMID:9620797, PMID:10882736, PMID:18434369, PMID:20074556, PMID:22102369 NCBI chr10:89,166,170...89,168,962
Ensembl chr10:89,166,890...89,168,965
JBrowse link
G Ramp3 receptor activity modifying protein 3 ISO UniProtKB:Q16602 (PMID:10882736)
UniProtKB:Q8WN93 (PMID:18434369)
RGD PMID:10882736, PMID:18434369 NCBI chr14:86,922,223...86,939,722
Ensembl chr14:86,922,223...86,939,719
JBrowse link
amylin receptor signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adm adrenomedullin ISO ComplexPortal:CPX-3186|UniProtKB:O60894|UniProtKB:O60895|UniProtKB:P30988 (PMID:22500019) RGD PMID:22500019 NCBI chr 1:175,443,189...175,447,260
Ensembl chr 1:175,445,088...175,447,259
JBrowse link
G Calca calcitonin-related polypeptide alpha ISO ComplexPortal:CPX-2173|UniProtKB:O60894|UniProtKB:P30988 (PMID:22500019) RGD PMID:22500019 NCBI chr 1:184,184,018...184,188,922
Ensembl chr 1:184,184,020...184,188,911
JBrowse link
G Calcr calcitonin receptor ISO ComplexPortal:CPX-1134|ComplexPortal:CPX-2173|UniProtKB:O60894|UniProtKB:O60895|UniProtKB:O60896|UniProtKB:P06881|UniProtKB:P10997:PRO_0000004106|UniProtKB:P12969:PRO_0000004122|UniProtKB:P35318 (PMID:14722252), (PMID:22500019) RGD PMID:14722252, PMID:22500019 NCBI chr 4:28,627,439...28,702,559
Ensembl chr 4:28,627,442...28,702,559
JBrowse link
G Iapp islet amyloid polypeptide IGI
ISO
PMID:22500019
ComplexPortal:CPX-2173|ComplexPortal:CPX-3187|UniProtKB:O60894|UniProtKB:O60896|UniProtKB:P30988 (PMID:22500019)
RGD PMID:22500019, PMID:22500019, PMID:22500019, PMID:22500019, PMID:22500019 RGD:12907560, RGD:12907560, RGD:12907560, RGD:12907560 NCBI chr 4:176,509,863...176,517,903
Ensembl chr 4:176,510,696...176,516,083
JBrowse link
G Ramp1 receptor activity modifying protein 1 ISO UniProtKB:P06881|UniProtKB:P10997:PRO_0000004106|UniProtKB:P12969:PRO_0000004122|UniProtKB:P30988|UniProtKB:P35318 (PMID:14722252), (PMID:22500019) RGD PMID:14722252, PMID:22500019 NCBI chr 9:98,313,632...98,364,206
Ensembl chr 9:98,313,632...98,364,205
JBrowse link
G Ramp2 receptor activity modifying protein 2 ISO UniProtKB:P12969:PRO_0000004122|UniProtKB:P30988|UniProtKB:P35318 (PMID:22500019) RGD PMID:22500019 NCBI chr10:89,166,170...89,168,962
Ensembl chr10:89,166,890...89,168,965
JBrowse link
G Ramp3 receptor activity modifying protein 3 ISO ComplexPortal:CPX-1134|UniProtKB:P10997:PRO_0000004106|UniProtKB:P30988 (PMID:22500019) RGD PMID:22500019 NCBI chr14:86,922,223...86,939,722
Ensembl chr14:86,922,223...86,939,719
JBrowse link
calcitonin gene-related peptide receptor signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Calca calcitonin-related polypeptide alpha ISO (PMID:10882736) RGD PMID:10882736 NCBI chr 1:184,184,018...184,188,922
Ensembl chr 1:184,184,020...184,188,911
JBrowse link
G Calcrl calcitonin receptor like receptor ISO UniProtKB:O60894 (PMID:10882736), (PMID:9620797)
UniProtKB:Q867C0 (PMID:18434369)
RGD PMID:9620797, PMID:10882736, PMID:18434369 NCBI chr 3:71,747,938...71,845,487
Ensembl chr 3:71,747,956...71,845,232
JBrowse link
G Ramp1 receptor activity modifying protein 1 ISO UniProtKB:Q16602 (PMID:10882736), (PMID:9620797) RGD PMID:9620797, PMID:10882736 NCBI chr 9:98,313,632...98,364,206
Ensembl chr 9:98,313,632...98,364,205
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20020
    signaling 7579
      signal transduction 7010
        G protein-coupled receptor signaling pathway 2509
          calcitonin family receptor signaling pathway 8
            adrenomedullin receptor signaling pathway 4
            amylin receptor signaling pathway + 7
            calcitonin gene-related peptide receptor signaling pathway 3
Path 2
Term Annotations click to browse term
  biological_process 20020
    biological regulation 13769
      regulation of biological process 13071
        regulation of cellular process 12556
          signal transduction 7010
            G protein-coupled receptor signaling pathway 2509
              calcitonin family receptor signaling pathway 8
                adrenomedullin receptor signaling pathway 4
                amylin receptor signaling pathway + 7
                calcitonin gene-related peptide receptor signaling pathway 3
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.