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ONTOLOGY REPORT - ANNOTATIONS


Term:calcitonin family receptor signaling pathway
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Accession:GO:0097646 term browser browse the term
Definition:A series of molecular signals initiated by an extracellular member of the calcitonin family (e.g. adrenomedullin, adrenomedullin 2 (intermedin), amylin, calcitonin and calcitonin gene-related peptides (CGRPs)) combining with a calcitonin family receptor on the surface of the target cell. Calcitonin family receptors may form dimers, trimers or tetramers; adrenomedullin and amylin receptors have only been observed as dimers so far.
Synonyms:exact_synonym: calcitonin family receptor signalling pathway


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adrenomedullin receptor signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ADM adrenomedullin JBrowse link 11 10,305,073 10,307,397 RGD:2290271
G CALCRL calcitonin receptor like receptor JBrowse link 2 187,341,964 187,448,304 RGD:2290271
G RAMP2 receptor activity modifying protein 2 JBrowse link 17 42,761,227 42,763,041 RGD:2290271
G RAMP3 receptor activity modifying protein 3 JBrowse link 7 45,157,778 45,184,250 RGD:2290271
amylin receptor signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ADM adrenomedullin JBrowse link 11 10,305,073 10,307,397 RGD:2290271
G CALCA calcitonin related polypeptide alpha JBrowse link 11 14,966,668 14,972,361 RGD:2290271
G CALCR calcitonin receptor JBrowse link 7 93,424,486 93,574,730 RGD:2290271
G IAPP islet amyloid polypeptide JBrowse link 12 21,354,960 21,379,980 RGD:2290271
G RAMP1 receptor activity modifying protein 1 JBrowse link 2 237,858,555 237,912,114 RGD:2290271
G RAMP2 receptor activity modifying protein 2 JBrowse link 17 42,761,227 42,763,041 RGD:2290271
G RAMP3 receptor activity modifying protein 3 JBrowse link 7 45,157,778 45,184,250 RGD:2290271
calcitonin gene-related peptide receptor signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CALCA calcitonin related polypeptide alpha JBrowse link 11 14,966,668 14,972,361 RGD:2290271
G CALCRL calcitonin receptor like receptor JBrowse link 2 187,341,964 187,448,304 RGD:2290271
G RAMP1 receptor activity modifying protein 1 JBrowse link 2 237,858,555 237,912,114 RGD:2290271

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17540
    signaling 6568
      signal transduction 6089
        G protein-coupled receptor signaling pathway 1353
          calcitonin family receptor signaling pathway 8
            adrenomedullin receptor signaling pathway 4
            amylin receptor signaling pathway + 7
            calcitonin gene-related peptide receptor signaling pathway 3
Path 2
Term Annotations click to browse term
  biological_process 17540
    biological regulation 12166
      regulation of biological process 11500
        regulation of cellular process 10804
          signal transduction 6089
            G protein-coupled receptor signaling pathway 1353
              calcitonin family receptor signaling pathway 8
                adrenomedullin receptor signaling pathway 4
                amylin receptor signaling pathway + 7
                calcitonin gene-related peptide receptor signaling pathway 3
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.