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ONTOLOGY REPORT - ANNOTATIONS


Term:serpin family protein binding
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Accession:GO:0097655 term browser browse the term
Definition:Interacting selectively and non-covalently with any member of the serpin protein family (serine protease inhibitors or classified inhibitor family I4). Serpins are a broadly distributed family of protease inhibitors that use a conformational change to inhibit target enzymes. They are central in controlling many important proteolytic cascades. The majority of serpins inhibit serine proteases, but serpins that inhibit caspases and papain-like cysteine proteases have also been identified. Rarely, serpins perform a non-inhibitory function; for example, several human serpins function as hormone transporters and certain serpins function as molecular chaperones or tumor suppressors.


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serpin family protein binding term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ctsl cathepsin L JBrowse link 17 1,873,105 1,879,266 RGD:1624291

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  molecular_function 19527
    binding 15910
      protein binding 12625
        serpin family protein binding 1
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.