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ONTOLOGY REPORT - ANNOTATIONS


Term:G protein-coupled serotonin receptor signaling pathway
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Accession:GO:0098664 term browser browse the term
Definition:The series of molecular signals generated as a consequence of a G protein-coupled serotonin receptor binding to one of its physiological ligands.


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G protein-coupled serotonin receptor signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chrm1 cholinergic receptor, muscarinic 1 IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 1:224,869,087...224,885,101
Ensembl chr 1:224,882,439...224,884,205
JBrowse link
G Chrm2 cholinergic receptor, muscarinic 2 IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 4:64,089,028...64,091,090
Ensembl chr 4:64,088,900...64,091,090
JBrowse link
G Chrm3 cholinergic receptor, muscarinic 3 IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr17:63,990,599...64,463,222
Ensembl chr17:63,990,599...63,994,169
JBrowse link
G Chrm4 cholinergic receptor, muscarinic 4 IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 3:80,833,272...80,841,165
Ensembl chr 3:80,833,272...80,841,006
JBrowse link
G Chrm5 cholinergic receptor, muscarinic 5 IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 3:103,966,451...104,018,815
Ensembl chr 3:103,966,451...104,018,861
JBrowse link
G Drd1 dopamine receptor D1 IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr17:11,099,736...11,104,352
Ensembl chr17:11,101,306...11,103,541
JBrowse link
G Drd4 dopamine receptor D4 IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 1:214,278,296...214,282,818
Ensembl chr 1:214,278,296...214,281,483
JBrowse link
G Hrh1 histamine receptor H 1 IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 4:146,374,596...146,458,148
Ensembl chr 4:146,455,332...146,457,074
JBrowse link
G Hrh2 histamine receptor H 2 IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr17:10,912,959...10,931,389
Ensembl chr17:10,921,507...10,952,441
JBrowse link
G Hrh3 histamine receptor H3 IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 3:175,474,310...175,479,395
Ensembl chr 3:175,473,078...175,479,395
JBrowse link
G Hrh4 histamine receptor H4 IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr18:4,365,429...4,382,599
Ensembl chr18:4,365,429...4,382,599
JBrowse link
G Htr1a 5-hydroxytryptamine receptor 1A IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 2:36,246,628...36,247,896
Ensembl chr 2:36,246,628...36,247,896
JBrowse link
G Htr1f 5-hydroxytryptamine receptor 1F IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr11:1,982,113...1,983,513
Ensembl chr11:1,982,113...1,983,513
JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A ISO (PMID:18703043) RGD PMID:18703043 NCBI chr15:56,666,152...56,732,469
Ensembl chr15:56,666,012...56,735,382
JBrowse link
G Htr2b 5-hydroxytryptamine receptor 2B ISO
ISS
(PMID:18703043), (PMID:7926008)
GO_REF:0000024
RGD
UniProt
PMID:7926008, PMID:18703043 GO_REF:0000024 NCBI chr 9:93,112,781...93,130,135
Ensembl chr 9:93,112,805...93,125,014
JBrowse link
G Htr2c 5-hydroxytryptamine receptor 2C IEA
ISO
GO_REF:0000108
(PMID:18703043)
GOC
RGD
PMID:18703043 GO_REF:0000108 NCBI chr  X:118,084,520...118,318,040
Ensembl chr  X:118,084,890...118,318,039
JBrowse link
G Htr4 5-hydroxytryptamine receptor 4 IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr18:57,637,013...57,820,317
Ensembl chr18:57,654,290...57,819,698
JBrowse link
G Htr6 5-hydroxytryptamine receptor 6 IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 5:157,501,202...157,518,870
Ensembl chr 5:157,503,040...157,518,631
JBrowse link
G Htr7 5-hydroxytryptamine receptor 7 IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 1:254,547,964...254,671,811
Ensembl chr 1:254,547,620...254,671,778
JBrowse link
G LOC100909683 olfactory receptor 63-like IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 7:15,722,054...15,723,428
Ensembl chr 7:15,722,177...15,723,127
JBrowse link
G LOC103693822 olfactory receptor 11H4-like IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr15:27,589,957...27,590,931
Ensembl chr15:27,499,024...27,499,998
Ensembl chr15:27,499,024...27,499,998
JBrowse link
G LOC103694905 5-hydroxytryptamine receptor 7 IEA GO_REF:0000108 GOC GO_REF:0000108
G Olr1090 olfactory receptor 1090 IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 7:15,523,926...15,524,635
Ensembl chr 7:15,523,926...15,706,893
JBrowse link
G Olr1091 olfactory receptor 1091 IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 7:15,628,665...15,629,600
Ensembl chr 7:15,628,665...15,629,600
JBrowse link
G Olr1095 olfactory receptor 1095 IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 7:15,621,989...15,622,945
Ensembl chr 7:15,621,989...15,622,945
JBrowse link
G Olr1576 olfactory receptor 1576 IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr13:91,481,461...91,482,390
Ensembl chr13:91,481,461...91,482,390
JBrowse link
G Olr1622 olfactory receptor 1622 IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr15:27,438,853...27,439,791
Ensembl chr15:27,438,853...27,439,791
JBrowse link
G Olr1631 olfactory receptor 1631 IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr15:27,484,665...27,485,639
Ensembl chr15:27,484,665...27,485,639
JBrowse link
G Olr1632 olfactory receptor 1632 IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr15:27,499,024...27,499,998
Ensembl chr15:27,499,024...27,499,998
JBrowse link
G Olr1635 olfactory receptor 1635 IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr15:27,548,762...27,549,748
Ensembl chr15:27,548,762...27,549,748
JBrowse link
G Olr1875 olfactory receptor 1875 IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 1:172,877,048...172,878,013
Ensembl chr 1:172,877,087...172,878,013
JBrowse link
G Olr240 olfactory receptor 240 IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 1:172,094,587...172,100,921
Ensembl chr 1:172,099,992...172,100,921
JBrowse link
G Olr241 olfactory receptor 241 IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 1:172,129,514...172,130,446
Ensembl chr 1:172,129,514...172,130,446
JBrowse link
G Olr245 olfactory receptor 245 IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 1:172,242,504...172,243,487
Ensembl chr 1:172,242,504...172,243,487
JBrowse link
G Olr515 olfactory receptor 515 IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 3:73,988,945...73,989,910
Ensembl chr 3:73,988,945...73,989,910
JBrowse link
G Olr517 olfactory receptor 517 IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 3:74,052,884...74,059,247
Ensembl chr 3:74,058,255...74,059,247
JBrowse link
G Olr518 olfactory receptor 518 IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 3:74,370,435...74,379,077
Ensembl chr 3:74,370,435...74,371,385
JBrowse link
G Olr519 olfactory receptor 519 IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 3:74,341,751...74,342,719
Ensembl chr 3:74,341,751...74,342,719
JBrowse link
adenylate cyclase-inhibiting serotonin receptor signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Htr1a 5-hydroxytryptamine receptor 1A IMP
IBA
ISO
PMID:21873635
(PMID:8393041)
RGD PMID:8393041, PMID:8271204, PMID:21873635 RGD:2303617, RGD:13792537 NCBI chr 2:36,246,628...36,247,896
Ensembl chr 2:36,246,628...36,247,896
JBrowse link
G Htr1b 5-hydroxytryptamine receptor 1B ISO
IBA
ISS
(PMID:1315531)
PMID:21873635
GO_REF:0000024
RGD
UniProt
PMID:1315531, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 8:89,113,984...89,130,830
Ensembl chr 8:89,129,453...89,130,991
JBrowse link
G Htr1d 5-hydroxytryptamine receptor 1D IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:154,780,958...154,801,505
Ensembl chr 5:154,800,226...154,801,350
JBrowse link
G Htr1f 5-hydroxytryptamine receptor 1F IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr11:1,982,113...1,983,513
Ensembl chr11:1,982,113...1,983,513
JBrowse link
G Htr4 5-hydroxytryptamine receptor 4 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr18:57,637,013...57,820,317
Ensembl chr18:57,654,290...57,819,698
JBrowse link
G Htr5a 5-hydroxytryptamine receptor 5A IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:199,916...209,599
Ensembl chr 4:199,916...209,599
JBrowse link
G Htr5b 5-hydroxytryptamine (serotonin) receptor 5B IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr13:37,479,758...37,492,680
Ensembl chr13:37,479,758...37,492,680
JBrowse link
phospholipase C-activating serotonin receptor signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Htr2a 5-hydroxytryptamine receptor 2A IDA RGD PMID:17010161 RGD:1624387 NCBI chr15:56,666,152...56,732,469
Ensembl chr15:56,666,012...56,735,382
JBrowse link
G Htr2b 5-hydroxytryptamine receptor 2B ISO
IEA
(PMID:12970106)
GO_REF:0000107
RGD
Ensembl
PMID:12970106 GO_REF:0000107 NCBI chr 9:93,112,781...93,130,135
Ensembl chr 9:93,112,805...93,125,014
JBrowse link
G Htr2c 5-hydroxytryptamine receptor 2C IDA
ISO
(MGI:5140621|PMID:21835345)
(PMID:12970106)
RGD PMID:12970106, PMID:21835345, PMID:12435801 MGI:5140621, RGD:1598460 NCBI chr  X:118,084,520...118,318,040
Ensembl chr  X:118,084,890...118,318,039
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20020
    cellular process 18792
      signal transduction 7010
        serotonin receptor signaling pathway 45
          G protein-coupled serotonin receptor signaling pathway 42
            adenylate cyclase-inhibiting serotonin receptor signaling pathway 7
            phospholipase C-activating serotonin receptor signaling pathway 3
Path 2
Term Annotations click to browse term
  biological_process 20020
    response to stimulus 10580
      response to chemical 6337
        response to nitrogen compound 1552
          response to organonitrogen compound 1456
            cellular response to organonitrogen compound 848
              cellular response to monoamine stimulus 111
                cellular response to catecholamine stimulus 111
                  cellular response to dopamine 92
                    serotonin receptor signaling pathway 45
                      G protein-coupled serotonin receptor signaling pathway 42
                        adenylate cyclase-inhibiting serotonin receptor signaling pathway 7
                        phospholipase C-activating serotonin receptor signaling pathway 3
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.