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ONTOLOGY REPORT - ANNOTATIONS


Term:detoxification
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Accession:GO:0098754 term browser browse the term
Definition:Any process that reduces or removes the toxicity of a toxic substance. These may include transport of the toxic substance away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance.


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aflatoxin catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G NFE2L2 nuclear factor, erythroid 2 like 2 JBrowse link 2B 182,214,116 182,248,282 RGD:9068941
cellular detoxification of aldehyde term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AKR1A1 aldo-keto reductase family 1 member A1 JBrowse link 1 46,211,859 46,230,072 RGD:9068941
G AKR1B10 aldo-keto reductase family 1 member B10 JBrowse link 7 138,992,802 139,006,042 RGD:9068941
G RDH11 retinol dehydrogenase 11 JBrowse link 14 67,135,366 67,154,286 RGD:9068941
G RDH12 retinol dehydrogenase 12 JBrowse link 14 67,180,696 67,192,345 RGD:9068941
cellular detoxification of nitrogen compound term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G GSTM1 glutathione S-transferase mu 1 JBrowse link 1 128,003,736 128,009,696 RGD:9068941
G GSTM2 glutathione S-transferase mu 2 JBrowse link 1 111,272,713 111,278,829 RGD:9068941
G GSTM3 glutathione S-transferase mu 3 JBrowse link 1 127,956,485 127,960,583 RGD:9068941
cellular oxidant detoxification term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ALB albumin JBrowse link 4 56,605,322 56,622,418 RGD:9068941
G ALOX5AP arachidonate 5-lipoxygenase activating protein JBrowse link 13 30,425,510 30,476,607 RGD:9068941
G APOE apolipoprotein E JBrowse link 19 50,459,906 50,463,490 RGD:9068941
G APOM apolipoprotein M JBrowse link 6 32,203,435 32,209,249 RGD:9068941
G CAT catalase JBrowse link 11 34,289,603 34,323,160 RGD:9068941
G CLIC2 chloride intracellular channel 2 JBrowse link X 154,581,649 154,641,515 RGD:9068941
G CYGB cytoglobin JBrowse link 17 76,167,003 76,178,247 RGD:9068941
G DUOX1 dual oxidase 1 JBrowse link 15 42,432,792 42,466,446 RGD:9068941
G DUOX2 dual oxidase 2 JBrowse link 15 42,393,643 42,414,281 RGD:9068941
G EPX eosinophil peroxidase JBrowse link 17 57,124,920 57,136,992 RGD:9068941
G FABP1 fatty acid binding protein 1 JBrowse link 2A 89,165,308 89,170,448 RGD:9068941
G GPX1 glutathione peroxidase 1 JBrowse link 3 50,360,736 50,362,274 RGD:9068941
G GPX2 glutathione peroxidase 2 JBrowse link 14 64,401,921 64,405,720 RGD:9068941
G GPX3 glutathione peroxidase 3 JBrowse link 5 152,450,426 152,458,994 RGD:9068941
G GPX4 glutathione peroxidase 4 JBrowse link 19 1,082,917 1,085,538 RGD:9068941
G GPX5 glutathione peroxidase 5 JBrowse link 6 29,010,528 29,018,737 RGD:9068941
G GPX6 glutathione peroxidase 6 JBrowse link 6 28,988,742 29,000,265 RGD:9068941
G GPX7 glutathione peroxidase 7 JBrowse link 1 53,471,583 53,478,074 RGD:9068941
G GPX8 glutathione peroxidase 8 (putative) JBrowse link 5 60,484,850 60,492,005 RGD:9068941
G GSR glutathione-disulfide reductase JBrowse link 8 27,180,294 27,229,557 RGD:9068941
G GSTK1 glutathione S-transferase kappa 1 JBrowse link 7 147,749,461 147,755,158 RGD:9068941
G GSTM2 glutathione S-transferase mu 2 JBrowse link 1 111,272,713 111,278,829 RGD:9068941
G GSTO1 glutathione S-transferase omega 1 JBrowse link 10 104,312,403 104,325,733 RGD:9068941
G GSTO2 glutathione S-transferase omega 2 JBrowse link 10 104,326,174 104,357,604 RGD:9068941
G GSTP1 glutathione S-transferase pi 1 JBrowse link 11 66,253,421 66,256,472 RGD:9068941
G GSTZ1 glutathione S-transferase zeta 1 JBrowse link 14 77,075,814 77,102,745 RGD:9068941
G HBM hemoglobin subunit mu JBrowse link 16 157,767 158,559 RGD:9068941
G HBQ1 hemoglobin subunit theta 1 JBrowse link 16 170,684 171,524 RGD:9068941
G HBZ hemoglobin subunit zeta JBrowse link 16 153,942 155,975 RGD:9068941
G IYD iodotyrosine deiodinase JBrowse link 6 152,886,367 152,922,152 RGD:9068941
G KDM3B lysine demethylase 3B JBrowse link 5 139,863,961 139,947,895 RGD:9068941
G LOXHD1 lipoxygenase homology domains 1 JBrowse link 18 43,290,361 43,469,923 RGD:9068941
G LPO lactoperoxidase JBrowse link 17 57,171,304 57,199,735 RGD:9068941
G LTC4S leukotriene C4 synthase JBrowse link 5 182,256,113 182,261,003 RGD:9068941
G MGST1 microsomal glutathione S-transferase 1 JBrowse link 12 16,743,739 16,773,290 RGD:9068941
G MGST2 microsomal glutathione S-transferase 2 JBrowse link 4 143,338,016 143,412,966 RGD:9068941
G MGST3 microsomal glutathione S-transferase 3 JBrowse link 1 144,852,428 144,876,800 RGD:9068941
G MPO myeloperoxidase JBrowse link 17 57,189,654 57,212,111 RGD:9068941
G NNT nicotinamide nucleotide transhydrogenase JBrowse link 5 71,719,257 71,823,259 RGD:9068941
G NXN nucleoredoxin JBrowse link 17 690,089 720,659 RGD:9068941
G PARK7 Parkinsonism associated deglycase JBrowse link 1 7,969,265 7,993,271 RGD:9068941
G PRDX1 peroxiredoxin 1 JBrowse link 1 46,171,453 46,182,018 RGD:9068941
G PRDX2 peroxiredoxin 2 JBrowse link 19 13,103,422 13,107,369 RGD:9068941
G PRDX3 peroxiredoxin 3 JBrowse link 10 119,162,714 119,173,845 RGD:9068941
G PRDX4 peroxiredoxin 4 JBrowse link X 23,641,701 23,660,267 RGD:9068941
G PRDX5 peroxiredoxin 5 JBrowse link 11 63,020,097 63,023,624 RGD:9068941
G PRDX6 peroxiredoxin 6 JBrowse link 1 152,694,606 152,706,521 RGD:9068941
G PRXL2A peroxiredoxin like 2A JBrowse link 10 80,407,861 80,432,032 RGD:9068941
G PRXL2B peroxiredoxin like 2B JBrowse link 1 2,457,130 2,463,858 RGD:9068941
G PRXL2C peroxiredoxin like 2C JBrowse link 9 95,857,770 95,889,532 RGD:9068941
G PTGS1 prostaglandin-endoperoxide synthase 1 JBrowse link 9 121,837,095 121,859,283 RGD:9068941
G PTGS2 prostaglandin-endoperoxide synthase 2 JBrowse link 1 166,355,845 166,364,517 RGD:9068941
G PXDN peroxidasin JBrowse link 2A 1,582,193 1,692,033 RGD:9068941
G PXDNL peroxidasin like JBrowse link 8 45,132,928 45,366,150 RGD:9068941
G RP1 RP1 axonemal microtubule associated JBrowse link 8 48,414,160 48,428,421 RGD:9068941
G S100A9 S100 calcium binding protein A9 JBrowse link 1 132,338,246 132,341,497 RGD:9068941
G SELENOS selenoprotein S JBrowse link 15 99,279,195 99,285,682 RGD:9068941
G SELENOT selenoprotein T JBrowse link 3 155,194,428 155,221,577 RGD:9068941
G SELENOW selenoprotein W JBrowse link 1 31,397,890 31,412,050 RGD:9068941
G SESN1 sestrin 1 JBrowse link 6 110,839,631 110,945,723 RGD:9068941
G SESN2 sestrin 2 JBrowse link 1 28,555,072 28,577,931 RGD:9068941
G SRXN1 sulfiredoxin 1 JBrowse link 20 625,376 631,950 RGD:9068941
G TP53INP1 tumor protein p53 inducible nuclear protein 1 JBrowse link 8 93,747,162 93,767,196 RGD:9068941
G TPO thyroid peroxidase JBrowse link 2A 1,334,608 1,493,308 RGD:9068941
G TXN thioredoxin JBrowse link 9 109,565,557 109,578,311 RGD:9068941
G TXNDC17 thioredoxin domain containing 17 JBrowse link 17 6,666,067 6,668,475 RGD:9068941
G TXNDC2 thioredoxin domain containing 2 JBrowse link 18 6,681,552 6,683,778 RGD:9068941
G TXNRD1 thioredoxin reductase 1 JBrowse link 12 105,258,828 105,321,112 RGD:9068941
G TXNRD2 thioredoxin reductase 2 JBrowse link 22 18,310,134 18,375,681 RGD:9068941
G TXNRD3 thioredoxin reductase 3 JBrowse link 3 130,966,614 131,013,117 RGD:9068941
G UBIAD1 UbiA prenyltransferase domain containing 1 JBrowse link 1 11,260,412 11,283,070 RGD:9068941
detoxification of cadmium ion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G SLC30A1 solute carrier family 30 member 1 JBrowse link 1 192,002,503 192,009,515 RGD:9068941
detoxification of copper ion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ATP7A ATPase copper transporting alpha JBrowse link X 77,205,579 77,342,762 RGD:9068941
G LOC100986475 metallothionein-2 JBrowse link 16 56,027,016 56,028,093 RGD:9068941
G MT1E metallothionein 1E JBrowse link 16 56,043,244 56,044,880 RGD:9068941
G MT1HL1 metallothionein 1H like 1 JBrowse link 1 217,566,173 217,566,475 RGD:9068941
G MT3 metallothionein 3 JBrowse link 16 56,007,922 56,009,828 RGD:9068941
G MT4 metallothionein 4 JBrowse link 16 55,984,536 55,988,258 RGD:9068941
G PARK7 Parkinsonism associated deglycase JBrowse link 1 7,969,265 7,993,271 RGD:9068941
detoxification of mercury ion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PARK7 Parkinsonism associated deglycase JBrowse link 1 7,969,265 7,993,271 RGD:9068941
detoxification of nitrogen compound term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G MARC1 mitochondrial amidoxime reducing component 1 JBrowse link 1 201,407,483 201,435,186 RGD:9068941
G MARC2 mitochondrial amidoxime reducing component 2 JBrowse link 1 201,368,306 201,405,602 RGD:9068941
formaldehyde catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ADH4 alcohol dehydrogenase 4 (class II), pi polypeptide JBrowse link 4 102,186,670 102,206,923 RGD:9068941
G ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide JBrowse link 4 102,134,375 102,151,902 RGD:9068941
G ESD esterase D JBrowse link 13 46,633,619 46,660,364 RGD:9068941
guanine deglycation, methylglyoxal removal term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PARK7 Parkinsonism associated deglycase JBrowse link 1 7,969,265 7,993,271 RGD:9068941
phenylacetate catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ACAA1 acetyl-CoA acyltransferase 1 JBrowse link 3 38,302,976 38,317,009 RGD:9068941
G PON3 paraoxonase 3 JBrowse link 7 100,902,432 100,941,611 RGD:9068941
positive regulation of superoxide dismutase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PARK7 Parkinsonism associated deglycase JBrowse link 1 7,969,265 7,993,271 RGD:9068941
G RGN regucalcin JBrowse link X 47,371,225 47,388,881 RGD:9068941
G TNF tumor necrosis factor JBrowse link 6 32,126,618 32,129,389 RGD:9068941
regulation of removal of superoxide radicals term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BMP7 bone morphogenetic protein 7 JBrowse link 20 54,788,974 54,885,015 RGD:9068941
G CD36 CD36 molecule JBrowse link 7 86,228,856 86,305,865 RGD:9068941
G DHFR dihydrofolate reductase JBrowse link 5 34,938,548 34,967,003 RGD:9068941
G FBLN5 fibulin 5 JBrowse link 14 91,848,430 91,927,470 RGD:9068941
G GCH1 GTP cyclohydrolase 1 JBrowse link 14 53,706,723 53,767,393 RGD:9068941
G NFE2L2 nuclear factor, erythroid 2 like 2 JBrowse link 2B 182,214,116 182,248,282 RGD:9068941
regulation of superoxide dismutase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G SZT2 SZT2 subunit KICSTOR complex JBrowse link 1 44,068,936 44,130,135 RGD:9068941
removal of superoxide radicals term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G APOA4 apolipoprotein A4 JBrowse link 11 115,591,788 115,594,382 RGD:9068941
G ATP7A ATPase copper transporting alpha JBrowse link X 77,205,579 77,342,762 RGD:9068941
G CCS copper chaperone for superoxide dismutase JBrowse link 11 65,273,744 65,287,406 RGD:9068941
G FANCC FA complementation group C JBrowse link 9 94,327,355 94,544,772 RGD:9068941
G MPO myeloperoxidase JBrowse link 17 57,189,654 57,212,111 RGD:9068941
G MT3 metallothionein 3 JBrowse link 16 56,007,922 56,009,828 RGD:9068941
G NOS3 nitric oxide synthase 3 JBrowse link 7 154,730,009 154,755,233 RGD:9068941
G NQO1 NAD(P)H quinone dehydrogenase 1 JBrowse link 16 69,472,529 69,489,731 RGD:9068941
G PRDX1 peroxiredoxin 1 JBrowse link 1 46,171,453 46,182,018 RGD:9068941
G PRDX2 peroxiredoxin 2 JBrowse link 19 13,103,422 13,107,369 RGD:9068941
G SOD1 superoxide dismutase 1 JBrowse link 21 31,411,702 31,419,432 RGD:9068941
G SOD2 superoxide dismutase 2 JBrowse link 6 162,576,082 162,589,960 RGD:9068941
G SOD3 superoxide dismutase 3 JBrowse link 4 24,480,912 24,486,382 RGD:9068941

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15669
    detoxification 108
      cellular detoxification + 99
      cellular detoxification of methylglyoxal + 1
      detoxification of arsenic-containing substance 0
      detoxification of inorganic compound + 8
      detoxification of nitrogen compound + 5
      detoxification of zinc ion 0
      mycothiol-dependent detoxification 0
      toxin catabolic process + 3
Path 2
Term Annotations click to browse term
  biological_process 15669
    response to stimulus 8175
      response to chemical 4256
        response to toxic substance 487
          detoxification 108
            cellular detoxification + 99
            cellular detoxification of methylglyoxal + 1
            detoxification of arsenic-containing substance 0
            detoxification of inorganic compound + 8
            detoxification of nitrogen compound + 5
            detoxification of zinc ion 0
            mycothiol-dependent detoxification 0
            toxin catabolic process + 3
paths to the root