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ONTOLOGY REPORT - ANNOTATIONS


Term:detoxification
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Accession:GO:0098754 term browser browse the term
Definition:Any process that reduces or removes the toxicity of a toxic substance. These may include transport of the toxic substance away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance.


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aflatoxin catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nfe2l2 nuclear factor, erythroid 2 like 2 JBrowse link NW_004955403 19,510,122 19,536,428 RGD:9068941
cellular detoxification of aldehyde term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Akr1a1 aldo-keto reductase family 1 member A1 JBrowse link NW_004955464 12,715,238 12,729,034 RGD:9068941
G Rdh11 retinol dehydrogenase 11 JBrowse link NW_004955466 2,506,641 2,521,506 RGD:9068941
G Rdh12 retinol dehydrogenase 12 JBrowse link NW_004955466 2,473,145 2,485,779 RGD:9068941
cellular detoxification of nitrogen compound term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gstm3 glutathione S-transferase mu 3 JBrowse link NW_004955435 13,253,947 13,256,965 RGD:9068941
cellular oxidant detoxification term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Alb albumin JBrowse link NW_004955447 9,327 21,212 RGD:9068941
G Alox5ap arachidonate 5-lipoxygenase activating protein JBrowse link NW_004955431 15,071,535 15,097,496 RGD:9068941
G Apoe apolipoprotein E JBrowse link NW_004955555 1,998,170 2,002,003 RGD:9068941
G Apom apolipoprotein M JBrowse link NW_004955437 190,609 192,781 RGD:9068941
G Cat catalase JBrowse link NW_004955422 11,783,973 11,826,970 RGD:9068941
G Clic2 chloride intracellular channel 2 JBrowse link NW_004955594 374,332 393,802 RGD:9068941
G Cygb cytoglobin JBrowse link NW_004955506 5,766,006 5,775,722 RGD:9068941
G Duox1 dual oxidase 1 JBrowse link NW_004955409 8,228,754 8,256,575 RGD:9068941
G Duox2 dual oxidase 2 JBrowse link NW_004955409 8,270,657 8,288,201 RGD:9068941
G Epx eosinophil peroxidase JBrowse link NW_004955451 4,818,809 4,828,913 RGD:9068941
G Gpx1 glutathione peroxidase 1 JBrowse link NW_004955532 1,298,336 1,298,830 RGD:9068941
G Gpx2 glutathione peroxidase 2 JBrowse link NW_004955466 4,983,532 4,987,780 RGD:9068941
G Gpx3 glutathione peroxidase 3 JBrowse link NW_004955408 2,622,162 2,629,088 RGD:9068941
G Gpx4 glutathione peroxidase 4 JBrowse link NW_004955495 6,767,969 6,772,256 RGD:9068941
G Gpx7 glutathione peroxidase 7 JBrowse link NW_004955464 6,560,198 6,566,763 RGD:9068941
G Gpx8 glutathione peroxidase 8 (putative) JBrowse link NW_004955446 12,498,276 12,504,890 RGD:9068941
G Gsr glutathione-disulfide reductase JBrowse link NW_004955463 7,130,459 7,153,631 RGD:9068941
G Gstk1 glutathione S-transferase kappa 1 JBrowse link NW_004955494 383,107 387,483 RGD:9068941
G Gstp1 glutathione S-transferase pi 1 JBrowse link NW_004955422 17,914,228 17,916,918 RGD:9068941
G Gstz1 glutathione S-transferase zeta 1 JBrowse link NW_004955438 1,218,990 1,231,407 RGD:9068941
G Hbb hemoglobin subunit beta JBrowse link NW_004955414 21,188,012 21,189,363 RGD:9068941
G Hbq1 hemoglobin subunit theta 1 JBrowse link NW_004955442 17,000,811 17,004,033 RGD:9068941
G Ipcef1 interaction protein for cytohesin exchange factors 1 JBrowse link NW_004955439 7,666,246 7,836,481 RGD:9068941
G Iyd iodotyrosine deiodinase JBrowse link NW_004955439 10,998,797 11,060,078 RGD:9068941
G Kdm3b lysine demethylase 3B JBrowse link NW_004955418 2,026,254 2,098,223 RGD:9068941
G Loxhd1 lipoxygenase homology domains 1 JBrowse link NW_004955402 31,985,616 32,144,040 RGD:9068941
G Lpo lactoperoxidase JBrowse link NW_004955451 4,754,572 4,769,380 RGD:9068941
G Ltc4s leukotriene C4 synthase JBrowse link NW_004955408 788,856 791,505 RGD:9068941
G Mgst1 microsomal glutathione S-transferase 1 JBrowse link NW_004955413 12,989,935 13,005,203 RGD:9068941
G Mgst2 microsomal glutathione S-transferase 2 JBrowse link NW_004955428 4,006,054 4,049,497 RGD:9068941
G Mgst3 microsomal glutathione S-transferase 3 JBrowse link NW_004955462 11,024,678 11,041,851 RGD:9068941
G Mpo myeloperoxidase JBrowse link NW_004955451 4,743,744 4,753,358 RGD:9068941
G Nnt nicotinamide nucleotide transhydrogenase JBrowse link NW_004955446 18,685,511 18,778,024 RGD:9068941
G Nxn nucleoredoxin JBrowse link NW_004955481 2,338,005 2,481,557 RGD:9068941
G Park7 Parkinsonism associated deglycase JBrowse link NW_004955486 4,974,130 4,985,927 RGD:9068941
G Prdx1 peroxiredoxin 1 JBrowse link NW_004955464 12,761,390 12,773,413 RGD:9068941
G Prdx2 peroxiredoxin 2 JBrowse link NW_004955415 31,880,801 31,884,453 RGD:9068941
G Prdx3 peroxiredoxin 3 JBrowse link NW_004955431 23,640,775 23,651,738 RGD:9068941
G Prdx4 peroxiredoxin 4 JBrowse link NW_004955509 4,111,501 4,132,529 RGD:9068941
G Prdx5 peroxiredoxin 5 JBrowse link NW_004955422 20,763,822 20,766,976 RGD:9068941
G Prdx6 peroxiredoxin 6 JBrowse link NW_004955406 13,717,267 13,728,216 RGD:9068941
G Prxl2a peroxiredoxin like 2A JBrowse link NW_004955510 400,454 420,900 RGD:9068941
G Prxl2b peroxiredoxin like 2B JBrowse link NW_004955486 8,663,708 8,666,369 RGD:9068941
G Ptgs1 prostaglandin-endoperoxide synthase 1 JBrowse link NW_004955419 5,678,750 5,699,305 RGD:9068941
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link NW_004955406 25,077,988 25,086,259 RGD:9068941
G Pxdn peroxidasin JBrowse link NW_004955487 4,867,427 4,936,454 RGD:9068941
G Pxdnl peroxidasin like JBrowse link NW_004955454 10,993,294 11,442,351 RGD:9068941
G Rp1 RP1 axonemal microtubule associated JBrowse link NW_004955454 13,781,556 14,082,310 RGD:9068941
G S100a9 S100 calcium binding protein A9 JBrowse link NW_004955592 90,647 93,842 RGD:9068941
G Selenos selenoprotein S JBrowse link NW_004955416 28,152,984 28,162,173 RGD:9068941
G Selenot selenoprotein T JBrowse link NW_004955448 1,794,959 1,814,282 RGD:9068941
G Selenow selenoprotein W JBrowse link NW_004955574 1,522,304 1,526,862 RGD:9068941
G Sesn1 sestrin 1 JBrowse link NW_004955411 34,033,986 34,051,171 RGD:9068941
G Sesn2 sestrin 2 JBrowse link NW_004955452 7,392,644 7,417,204 RGD:9068941
G Srxn1 sulfiredoxin 1 JBrowse link NW_004955597 483,358 487,555 RGD:9068941
G Tp53inp1 tumor protein p53 inducible nuclear protein 1 JBrowse link NW_004955417 11,063,217 11,079,389 RGD:9068941
G Tpo thyroid peroxidase JBrowse link NW_004955487 485,029 530,287 RGD:9068941
G Txndc17 thioredoxin domain containing 17 JBrowse link NW_004955467 12,144,928 12,146,999 RGD:9068941
G Txndc2 thioredoxin domain containing 2 JBrowse link NW_004955402 2,339,130 2,341,283 RGD:9068941
G Txnrd1 thioredoxin reductase 1 JBrowse link NW_004955405 38,863,762 38,928,615 RGD:9068941
G Txnrd2 thioredoxin reductase 2 JBrowse link NW_004955442 18,150,060 18,205,775 RGD:9068941
G Txnrd3 thioredoxin reductase 3 JBrowse link NW_004955429 16,845,466 16,880,481 RGD:9068941
G Ubiad1 UbiA prenyltransferase domain containing 1 JBrowse link NW_004955486 2,472,035 2,481,975 RGD:9068941
detoxification of cadmium ion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Slc30a1 solute carrier family 30 member 1 JBrowse link NW_004955406 5,662,312 5,668,331 RGD:9068941
detoxification of copper ion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atp7a ATPase copper transporting alpha JBrowse link NW_004955557 1,355,471 1,515,725 RGD:9068941
G Park7 Parkinsonism associated deglycase JBrowse link NW_004955486 4,974,130 4,985,927 RGD:9068941
detoxification of mercury ion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Park7 Parkinsonism associated deglycase JBrowse link NW_004955486 4,974,130 4,985,927 RGD:9068941
formaldehyde catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Esd esterase D JBrowse link NW_004955431 524,491 551,871 RGD:9068941
guanine deglycation, methylglyoxal removal term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Park7 Parkinsonism associated deglycase JBrowse link NW_004955486 4,974,130 4,985,927 RGD:9068941
phenylacetate catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pon3 paraoxonase 3 JBrowse link NW_004955432 11,945,383 11,983,417 RGD:9068941
positive regulation of superoxide dismutase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Park7 Parkinsonism associated deglycase JBrowse link NW_004955486 4,974,130 4,985,927 RGD:9068941
G Rgn regucalcin JBrowse link NW_004955516 958,416 978,829 RGD:9068941
G Tnf tumor necrosis factor JBrowse link NW_004955437 117,267 119,899 RGD:9068941
regulation of removal of superoxide radicals term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmp7 bone morphogenetic protein 7 JBrowse link NW_004955445 2,154,057 2,235,594 RGD:9068941
G Cd36 CD36 molecule JBrowse link NW_004955410 5,003,720 5,120,903 RGD:9068941
G Dhfr dihydrofolate reductase JBrowse link NW_004955418 29,274,170 29,283,028 RGD:9068941
G Fbln5 fibulin 5 JBrowse link NW_004955438 14,073,927 14,144,644 RGD:9068941
G Gch1 GTP cyclohydrolase 1 JBrowse link NW_004955409 8,624,225 8,670,436 RGD:9068941
G Nfe2l2 nuclear factor, erythroid 2 like 2 JBrowse link NW_004955403 19,510,122 19,536,428 RGD:9068941
regulation of superoxide dismutase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Szt2 SZT2 subunit KICSTOR complex JBrowse link NW_004955537 2,968,839 3,017,863 RGD:9068941
removal of superoxide radicals term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Apoa4 apolipoprotein A4 JBrowse link NW_004955412 18,158,095 18,160,636 RGD:9068941
G Atp7a ATPase copper transporting alpha JBrowse link NW_004955557 1,355,471 1,515,725 RGD:9068941
G Ccs copper chaperone for superoxide dismutase JBrowse link NW_004955422 18,761,703 18,772,762 RGD:9068941
G Fancc FA complementation group C JBrowse link NW_004955422 22,031,825 22,246,478 RGD:9068941
G Mpo myeloperoxidase JBrowse link NW_004955451 4,743,744 4,753,358 RGD:9068941
G Nos3 nitric oxide synthase 3 JBrowse link NW_004955491 5,438,228 5,457,308 RGD:9068941
G Nqo1 NAD(P)H quinone dehydrogenase 1 JBrowse link NW_004955484 7,012,373 7,028,182 RGD:9068941
G Prdx1 peroxiredoxin 1 JBrowse link NW_004955464 12,761,390 12,773,413 RGD:9068941
G Prdx2 peroxiredoxin 2 JBrowse link NW_004955415 31,880,801 31,884,453 RGD:9068941
G Sod1 superoxide dismutase 1 JBrowse link NW_004955407 31,261,451 31,267,657 RGD:9068941
G Sod2 superoxide dismutase 2 JBrowse link NW_004955439 21,209,101 21,223,538 RGD:9068941
G Sod3 superoxide dismutase 3 JBrowse link NW_004955480 257,716 263,149 RGD:9068941

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 14490
    detoxification 88
      cellular detoxification + 86
      cellular detoxification of methylglyoxal + 1
      detoxification of arsenic-containing substance 0
      detoxification of inorganic compound + 3
      detoxification of nitrogen compound + 1
      detoxification of zinc ion 0
      mycothiol-dependent detoxification 0
      toxin catabolic process + 2
Path 2
Term Annotations click to browse term
  biological_process 14490
    response to stimulus 7601
      response to chemical 3903
        response to toxic substance 460
          detoxification 88
            cellular detoxification + 86
            cellular detoxification of methylglyoxal + 1
            detoxification of arsenic-containing substance 0
            detoxification of inorganic compound + 3
            detoxification of nitrogen compound + 1
            detoxification of zinc ion 0
            mycothiol-dependent detoxification 0
            toxin catabolic process + 2
paths to the root