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ONTOLOGY REPORT - ANNOTATIONS


Term:detoxification
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Accession:GO:0098754 term browser browse the term
Definition:Any process that reduces or removes the toxicity of a toxic substance. These may include transport of the toxic substance away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance.


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aflatoxin catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G NFE2L2 nuclear factor, erythroid 2 like 2 JBrowse link 36 20,989,205 21,087,044 RGD:9068941
cellular detoxification of aldehyde term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AKR1A1 aldo-keto reductase family 1 member A1 JBrowse link 15 14,792,398 14,808,805 RGD:9068941
G RDH11 retinol dehydrogenase 11 JBrowse link 8 41,651,970 41,669,661 RGD:13508589
RGD:9068941
G RDH12 retinol dehydrogenase 12 JBrowse link 8 41,685,045 41,696,120 RGD:9068941
cellular detoxification of nitrogen compound term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G LOC479911 glutathione S-transferase Mu 3 JBrowse link 6 42,187,869 42,191,274 RGD:13508589
RGD:9068941
cellular oxidant detoxification term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ALB albumin JBrowse link 13 62,133,747 62,169,349 RGD:9068941
G ALOX5AP arachidonate 5-lipoxygenase activating protein JBrowse link 25 9,320,868 9,351,056 RGD:9068941
G APOE apolipoprotein E JBrowse link 1 110,525,717 110,528,534 RGD:13508589
RGD:9068941
G APOM apolipoprotein M JBrowse link 12 1,137,474 1,142,337 RGD:13508589
RGD:9068941
G CAT catalase JBrowse link 18 33,383,005 33,422,447 RGD:13508589
RGD:9068941
G CLIC2 chloride intracellular channel 2 JBrowse link X 123,268,867 123,291,467 RGD:13508589
RGD:9068941
G CYGB cytoglobin JBrowse link 9 4,191,114 4,201,438 RGD:9068941
G DUOX1 dual oxidase 1 JBrowse link 30 11,556,024 11,588,203 RGD:13508589
RGD:9068941
G DUOX2 dual oxidase 2 JBrowse link 30 11,521,833 11,541,719 RGD:9068941
G EPX eosinophil peroxidase JBrowse link 9 32,855,568 32,865,445 RGD:9068941
G FABP1 fatty acid binding protein 1 JBrowse link 17 38,242,119 38,247,969 RGD:13508589
RGD:9068941
G GPX1 glutathione peroxidase 1 JBrowse link 20 39,889,165 39,890,253 RGD:9068941
G GPX2 glutathione peroxidase 2 JBrowse link 8 39,322,040 39,325,833 RGD:9068941
G GPX3 glutathione peroxidase 3 JBrowse link 4 58,200,671 58,209,010 RGD:9068941
G GPX5 glutathione peroxidase 5 JBrowse link 35 25,653,627 25,662,490 RGD:13508589
RGD:9068941
G GPX6 glutathione peroxidase 6 JBrowse link 35 25,620,843 25,630,288 RGD:9068941
G GPX7 glutathione peroxidase 7 JBrowse link 15 8,777,626 8,784,409 RGD:9068941
G GPX8 glutathione peroxidase 8 (putative) JBrowse link 2 42,532,171 42,537,449 RGD:13508589
RGD:9068941
G GSR glutathione-disulfide reductase JBrowse link 16 33,633,949 33,680,411 RGD:13508589
RGD:9068941
G GSTK1 glutathione S-transferase kappa 1 JBrowse link 16 6,411,678 6,416,135 RGD:9068941
RGD:13508589
G GSTO1 glutathione S-transferase omega 1 JBrowse link 28 16,569,421 16,579,239 RGD:13508589
RGD:9068941
G GSTO2 glutathione S-transferase omega 2 JBrowse link 28 16,580,250 16,604,977 RGD:9068941
G GSTP1 glutathione S-transferase pi 1 JBrowse link 18 49,905,161 49,908,182 RGD:9068941
G GSTZ1 glutathione S-transferase zeta 1 JBrowse link 8 50,133,496 50,143,487 RGD:9068941
G HBM hemoglobin subunit mu JBrowse link 6 40,330,773 40,331,500 RGD:13508589
RGD:9068941
G IYD iodotyrosine deiodinase JBrowse link 1 40,890,402 40,908,437 RGD:13508589
RGD:9068941
G KDM3B lysine demethylase 3B JBrowse link 11 25,954,352 26,024,919 RGD:9068941
G LOC100687127 thioredoxin-like JBrowse link X 82,986,288 82,986,753 RGD:9068941
G LOC100855540 hemoglobin subunit alpha-like JBrowse link 6 40,324,378 40,325,427 RGD:9068941
RGD:13508589
G LOC100855558 hemoglobin subunit alpha-like JBrowse link 6 40,328,053 40,329,002 RGD:13508589
G LOC100855600 hemoglobin subunit zeta-like JBrowse link 6 40,331,717 40,332,764 RGD:13508589
RGD:9068941
G LOC100855634 hemoglobin subunit zeta-like JBrowse link 6 40,342,517 40,343,540 RGD:13508589
G LOC479668 haptoglobin-like JBrowse link 5 77,795,183 77,800,034 RGD:9068941
G LOC485255 hemoglobin subunit epsilon-2 JBrowse link 21 28,193,163 28,194,746 RGD:9068941
G LOC609402 hemoglobin subunit beta-like JBrowse link 21 28,187,535 28,188,991 RGD:9068941
G LOXHD1 lipoxygenase homology domains 1 JBrowse link 7 44,662,800 44,828,405 RGD:9068941
G LPO lactoperoxidase JBrowse link 9 32,898,370 32,927,141 RGD:9068941
G LTC4S leukotriene C4 synthase JBrowse link 11 1,893,927 1,897,028 RGD:9068941
G MGST1 microsomal glutathione S-transferase 1 JBrowse link 27 30,370,588 30,391,898 RGD:13508589
RGD:9068941
G MGST2 microsomal glutathione S-transferase 2 JBrowse link 19 3,067,062 3,070,579 RGD:9068941
G MGST3 microsomal glutathione S-transferase 3 JBrowse link 38 17,670,329 17,691,822 RGD:9068941
G MPO myeloperoxidase JBrowse link 9 32,927,483 32,938,007 RGD:9068941
G NNT nicotinamide nucleotide transhydrogenase JBrowse link 4 66,348,222 66,437,889 RGD:9068941
G NXN nucleoredoxin JBrowse link 9 44,847,468 45,003,129 RGD:13508589
RGD:9068941
G PARK7 Parkinsonism associated deglycase JBrowse link 5 61,576,219 61,592,325 RGD:13508589
RGD:9068941
G PRDX1 peroxiredoxin 1 JBrowse link 15 14,834,009 14,855,665 RGD:9068941
G PRDX2 peroxiredoxin 2 JBrowse link 20 49,352,271 49,356,755 RGD:9068941
G PRDX3 peroxiredoxin 3 JBrowse link 28 29,395,593 29,403,745 RGD:13508589
RGD:9068941
G PRDX4 peroxiredoxin 4 JBrowse link X 19,361,658 19,383,718 RGD:13508589
RGD:9068941
G PRDX5 peroxiredoxin 5 JBrowse link 18 52,750,977 52,754,432 RGD:9068941
G PRDX6 peroxiredoxin 6 JBrowse link 7 25,663,238 25,675,855 RGD:9068941
G PRXL2A peroxiredoxin like 2A JBrowse link 4 29,539,182 29,559,353 RGD:9068941
G PRXL2B peroxiredoxin like 2B JBrowse link 5 57,429,973 57,434,371 RGD:13508589
RGD:9068941
G PRXL2C peroxiredoxin like 2C JBrowse link 1 70,199,278 70,209,026 RGD:9068941
G PTGS1 prostaglandin-endoperoxide synthase 1 JBrowse link 9 60,195,118 60,216,847 RGD:13508589
RGD:9068941
G PTGS2 prostaglandin-endoperoxide synthase 2 JBrowse link 7 19,668,079 19,674,903 RGD:13508589
RGD:9068941
G PXDN peroxidasin JBrowse link 17 834,625 891,551 RGD:9068941
G PXDNL peroxidasin like JBrowse link 29 3,277,291 3,706,964 RGD:9068941
G RP1 RP1 axonemal microtubule associated JBrowse link 29 6,079,519 6,136,009 RGD:13508589
RGD:9068941
G S100A9 S100 calcium binding protein A9 JBrowse link 7 43,566,993 43,570,074 RGD:9068941
G SELENOS selenoprotein S JBrowse link 3 39,796,711 39,805,654 RGD:9068941
G SELENOT selenoprotein T JBrowse link 23 45,247,088 45,271,229 RGD:9068941
G SELENOW selenoprotein W JBrowse link 1 108,285,443 108,289,551 RGD:9068941
G SESN1 sestrin 1 JBrowse link 12 65,958,995 66,057,369 RGD:13508589
RGD:9068941
G SESN2 sestrin 2 JBrowse link 2 72,151,464 72,168,861 RGD:13508589
RGD:9068941
G SRXN1 sulfiredoxin 1 JBrowse link 24 20,232,608 20,238,838 RGD:13508589
RGD:9068941
G TP53INP1 tumor protein p53 inducible nuclear protein 1 JBrowse link 29 39,575,782 39,593,389 RGD:13508589
RGD:9068941
G TPO thyroid peroxidase JBrowse link 17 773,790 810,044 RGD:13508589
RGD:9068941
G TXNDC17 thioredoxin domain containing 17 JBrowse link 5 30,701,673 30,703,742 RGD:9068941
G TXNDC2 thioredoxin domain containing 2 JBrowse link 7 75,822,005 75,824,032 RGD:9068941
G TXNRD1 thioredoxin reductase 1 JBrowse link 10 33,904,065 34,021,549 RGD:9068941
G TXNRD2 thioredoxin reductase 2 JBrowse link 26 29,381,823 29,430,239 RGD:9068941
G TXNRD3 thioredoxin reductase 3 JBrowse link 20 782,653 844,159 RGD:9068941
G UBIAD1 UbiA prenyltransferase domain containing 1 JBrowse link 2 84,803,338 84,813,030 RGD:9068941
detoxification of cadmium ion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G SLC30A1 solute carrier family 30 member 1 JBrowse link 7 9,952,373 9,959,382 RGD:9068941
detoxification of copper ion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ATP7A ATPase copper transporting alpha JBrowse link X 60,203,336 60,356,525 RGD:9068941
G LOC100686073 metallothionein-1 JBrowse link 2 59,603,021 59,604,173 RGD:9068941
G MT1E metallothionein 1E RGD:9068941
G MT2A metallothionein 1H JBrowse link 2 59,607,926 59,608,825 RGD:9068941
G MT4 metallothionein 4 JBrowse link 2 59,640,784 59,643,370 RGD:9068941
G PARK7 Parkinsonism associated deglycase JBrowse link 5 61,576,219 61,592,325 RGD:13508589
RGD:9068941
detoxification of mercury ion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PARK7 Parkinsonism associated deglycase JBrowse link 5 61,576,219 61,592,325 RGD:13508589
RGD:9068941
detoxification of nitrogen compound term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G MARC1 mitochondrial amidoxime reducing component 1 JBrowse link 38 15,460,548 15,490,941 RGD:9068941
G MARC2 mitochondrial amidoxime reducing component 2 JBrowse link 38 15,426,884 15,451,701 RGD:9068941
formaldehyde catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ADH4 alcohol dehydrogenase 4 (class II), pi polypeptide JBrowse link 32 21,282,526 21,299,387 RGD:9068941
G ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide JBrowse link 32 21,249,459 21,261,130 RGD:9068941
G ESD esterase D JBrowse link 22 4,544,657 4,569,986 RGD:13508589
RGD:9068941
guanine deglycation, methylglyoxal removal term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PARK7 Parkinsonism associated deglycase JBrowse link 5 61,576,219 61,592,325 RGD:13508589
RGD:9068941
phenylacetate catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ACAA1 acetyl-CoA acyltransferase 1 JBrowse link 23 7,889,481 7,901,324 RGD:9068941
G PON3 paraoxonase 3 JBrowse link 14 20,615,180 20,642,807 RGD:9068941
positive regulation of superoxide dismutase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PARK7 Parkinsonism associated deglycase JBrowse link 5 61,576,219 61,592,325 RGD:13508589
RGD:9068941
G RGN regucalcin JBrowse link X 40,697,292 40,715,491 RGD:9068941
G TNF tumor necrosis factor JBrowse link 12 1,074,561 1,076,425 RGD:13508589
RGD:9068941
regulation of removal of superoxide radicals term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BMP7 bone morphogenetic protein 7 JBrowse link 24 42,203,183 42,294,105 RGD:9068941
G CD36 CD36 molecule JBrowse link 18 20,299,808 20,375,856 RGD:13508589
RGD:9068941
G FBLN5 fibulin 5 JBrowse link 8 1,162,203 1,231,809 RGD:9068941
G GCH1 GTP cyclohydrolase 1 JBrowse link 8 30,733,422 30,784,067 RGD:13508589
RGD:9068941
G NFE2L2 nuclear factor, erythroid 2 like 2 JBrowse link 36 20,989,205 21,087,044 RGD:9068941
regulation of superoxide dismutase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G SZT2 SZT2 subunit of KICSTOR complex JBrowse link 15 16,729,068 16,780,549 RGD:13508589
RGD:9068941
removal of superoxide radicals term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G APOA4 apolipoprotein A4 JBrowse link 5 16,751,588 16,754,215 RGD:9068941
RGD:13508589
G ATP7A ATPase copper transporting alpha JBrowse link X 60,203,336 60,356,525 RGD:9068941
G CCS copper chaperone for superoxide dismutase JBrowse link 18 50,748,039 50,759,270 RGD:9068941
RGD:13508589
G FANCC FA complementation group C JBrowse link 1 71,388,931 71,678,019 RGD:9068941
G MPO myeloperoxidase JBrowse link 9 32,927,483 32,938,007 RGD:9068941
G NOS3 nitric oxide synthase 3 JBrowse link 16 15,054,196 15,072,454 RGD:9068941
G NQO1 NAD(P)H quinone dehydrogenase 1 JBrowse link 5 79,979,593 79,990,875 RGD:9068941
G PRDX1 peroxiredoxin 1 JBrowse link 15 14,834,009 14,855,665 RGD:9068941
G PRDX2 peroxiredoxin 2 JBrowse link 20 49,352,271 49,356,755 RGD:9068941
G SOD1 superoxide dismutase 1 JBrowse link 31 26,540,291 26,544,212 RGD:13508589
RGD:9068941
G SOD2 superoxide dismutase 2 JBrowse link 1 48,943,472 48,955,158 RGD:13508589
RGD:9068941
G SOD3 superoxide dismutase 3 JBrowse link 3 85,382,698 85,387,144 RGD:9068941

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15702
    detoxification 107
      cellular detoxification + 98
      cellular detoxification of methylglyoxal + 1
      detoxification of arsenic-containing substance 0
      detoxification of inorganic compound + 7
      detoxification of nitrogen compound + 3
      detoxification of zinc ion 0
      mycothiol-dependent detoxification 0
      toxin catabolic process + 3
Path 2
Term Annotations click to browse term
  biological_process 15702
    response to stimulus 8328
      response to chemical 4429
        response to toxic substance 495
          detoxification 107
            cellular detoxification + 98
            cellular detoxification of methylglyoxal + 1
            detoxification of arsenic-containing substance 0
            detoxification of inorganic compound + 7
            detoxification of nitrogen compound + 3
            detoxification of zinc ion 0
            mycothiol-dependent detoxification 0
            toxin catabolic process + 3
paths to the root