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ONTOLOGY REPORT - ANNOTATIONS


Term:detoxification
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Accession:GO:0098754 term browser browse the term
Definition:Any process that reduces or removes the toxicity of a toxic substance. These may include transport of the toxic substance away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance.


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aflatoxin catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gsta3 glutathione S-transferase, alpha 3 JBrowse link 1 21,240,585 21,265,575 RGD:2290270
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 JBrowse link 2 75,675,513 75,704,663 RGD:2290270
cellular detoxification of aldehyde term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Akr1a1 aldo-keto reductase family 1, member A1 (aldehyde reductase) JBrowse link 4 116,636,510 116,651,674 RGD:2290270
G Akr1b8 aldo-keto reductase family 1, member B8 JBrowse link 6 34,354,164 34,368,454 RGD:2290270
G Rdh11 retinol dehydrogenase 11 JBrowse link 12 79,175,551 79,191,819 RGD:2290270
G Rdh12 retinol dehydrogenase 12 JBrowse link 12 79,208,913 79,222,664 RGD:2290270
cellular detoxification of nitrogen compound term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gstm2 glutathione S-transferase, mu 2 JBrowse link 3 107,981,702 107,986,436 RGD:2290270
G Gstm5 glutathione S-transferase, mu 5 JBrowse link 3 107,895,854 107,898,685 RGD:2290270
G Gstm7 glutathione S-transferase, mu 7 JBrowse link 3 107,926,334 107,931,871 RGD:2290270
cellular oxidant detoxification term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Prdx6 peroxiredoxin 6 JBrowse link 1 161,240,112 161,251,210 RGD:2290270
G Selenot selenoprotein T JBrowse link 3 58,576,658 58,593,544 RGD:2290270
G Sesn1 sestrin 1 JBrowse link 10 41,810,574 41,908,436 RGD:2290270
detoxification of cadmium ion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Slc30a1 solute carrier family 30 (zinc transporter), member 1 JBrowse link 1 191,906,689 191,913,247 RGD:2290270
detoxification of copper ion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atp7a ATPase, Cu++ transporting, alpha polypeptide JBrowse link X 106,027,224 106,128,160 RGD:2290270
G Mt1 metallothionein 1 JBrowse link 8 94,179,084 94,180,327 RGD:2290270
G Mt2 metallothionein 2 JBrowse link 8 94,172,618 94,173,567 RGD:2290270
G Mt3 metallothionein 3 JBrowse link 8 94,152,607 94,154,148 RGD:2290270
G Mt4 metallothionein 4 JBrowse link 8 94,137,204 94,139,031 RGD:2290270
G Park7 Parkinson disease (autosomal recessive, early onset) 7 JBrowse link 4 150,897,133 150,909,921 RGD:2290270
detoxification of mercury ion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Park7 Parkinson disease (autosomal recessive, early onset) 7 JBrowse link 4 150,897,133 150,909,921 RGD:2290270
detoxification of zinc ion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Slc30a3 solute carrier family 30 (zinc transporter), member 3 JBrowse link 5 31,086,106 31,108,244 RGD:2290270
formaldehyde catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adh4 alcohol dehydrogenase 4 (class II), pi polypeptide JBrowse link 3 138,415,497 138,430,892 RGD:2290270
G Adh5 alcohol dehydrogenase 5 (class III), chi polypeptide JBrowse link 3 138,437,200 138,455,499 RGD:2290270
G Esd esterase D/formylglutathione hydrolase JBrowse link 14 74,732,297 74,750,765 RGD:2290270
guanine deglycation, methylglyoxal removal term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Park7 Parkinson disease (autosomal recessive, early onset) 7 JBrowse link 4 150,897,133 150,909,921 RGD:2290270
mercury ion transport term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcc2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 JBrowse link 19 43,782,308 43,838,332 RGD:2290270
phenylacetate catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acaa1a acetyl-Coenzyme A acyltransferase 1A JBrowse link 9 119,341,052 119,350,296 RGD:2290270
G Acaa1b acetyl-Coenzyme A acyltransferase 1B JBrowse link 9 119,148,043 119,157,093 RGD:2290270
G Pon3 paraoxonase 3 JBrowse link 6 5,220,852 5,256,242 RGD:2290270
positive regulation of superoxide dismutase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Park7 Parkinson disease (autosomal recessive, early onset) 7 JBrowse link 4 150,897,133 150,909,921 RGD:2290270
G Rgn regucalcin JBrowse link X 20,549,766 20,562,089 RGD:2290270
G Tnf tumor necrosis factor JBrowse link 17 35,199,367 35,202,007 RGD:2290270
regulation of removal of superoxide radicals term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd36 CD36 molecule JBrowse link 5 17,781,690 17,888,959 RGD:2290270
G Dhfr dihydrofolate reductase JBrowse link 13 92,354,783 92,389,053 RGD:2290270
G Fbln5 fibulin 5 JBrowse link 12 101,746,565 101,819,130 RGD:2290270
G Gch1 GTP cyclohydrolase 1 JBrowse link 14 47,153,895 47,189,402 RGD:2290270
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 JBrowse link 2 75,675,513 75,704,663 RGD:2290270
regulation of superoxide dismutase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Szt2 seizure threshold 2 JBrowse link 4 118,362,740 118,409,271 RGD:2290270
removal of superoxide radicals term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Apoa4 apolipoprotein A-IV JBrowse link 9 46,240,844 46,243,458 RGD:2290270
G Atp7a ATPase, Cu++ transporting, alpha polypeptide JBrowse link X 106,027,224 106,128,160 RGD:2290270
G Ccs copper chaperone for superoxide dismutase JBrowse link 19 4,825,366 4,839,327 RGD:2290270
G Fancc Fanconi anemia, complementation group C JBrowse link 13 63,304,705 63,497,294 RGD:2290270
G Gm5225 predicted gene 5225 JBrowse link 17 24,023,861 24,024,500 RGD:2290270
G Mpo myeloperoxidase JBrowse link 11 87,793,784 87,804,412 RGD:2290270
G Nos3 nitric oxide synthase 3, endothelial cell JBrowse link 5 24,364,819 24,384,474 RGD:2290270
G Prdx1 peroxiredoxin 1 JBrowse link 4 116,685,599 116,700,000 RGD:2290270
G Prdx2 peroxiredoxin 2 JBrowse link 8 84,969,622 84,974,811 RGD:2290270
G Sod1 superoxide dismutase 1, soluble JBrowse link 16 90,220,742 90,226,324 RGD:2290270
G Sod2 superoxide dismutase 2, mitochondrial JBrowse link 17 13,007,839 13,018,119 RGD:2290270
G Sod3 superoxide dismutase 3, extracellular JBrowse link 5 52,363,804 52,369,738 RGD:2290270

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 23031
    detoxification 45
      cellular detoxification + 34
      cellular detoxification of methylglyoxal + 1
      detoxification of arsenic-containing substance 0
      detoxification of inorganic compound + 8
      detoxification of nitrogen compound + 3
      detoxification of zinc ion 1
      mycothiol-dependent detoxification 0
      toxin catabolic process + 5
Path 2
Term Annotations click to browse term
  biological_process 23031
    response to stimulus 9419
      response to chemical 4084
        response to toxic substance 345
          detoxification 45
            cellular detoxification + 34
            cellular detoxification of methylglyoxal + 1
            detoxification of arsenic-containing substance 0
            detoxification of inorganic compound + 8
            detoxification of nitrogen compound + 3
            detoxification of zinc ion 1
            mycothiol-dependent detoxification 0
            toxin catabolic process + 5
paths to the root