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ONTOLOGY REPORT - ANNOTATIONS


Term:detoxification
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Accession:GO:0098754 term browser browse the term
Definition:Any process that reduces or removes the toxicity of a toxic substance. These may include transport of the toxic substance away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance.


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aflatoxin catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nfe2l2 nuclear factor, erythroid 2 like 2 JBrowse link NW_004936509 6,589,967 6,621,171 RGD:9068941
cellular detoxification of aldehyde term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Akr1a1 aldo-keto reductase family 1 member A1 JBrowse link NW_004936474 26,680,736 26,696,996 RGD:9068941
G Rdh11 retinol dehydrogenase 11 JBrowse link NW_004936495 11,065,946 11,082,104 RGD:9068941
G Rdh12 retinol dehydrogenase 12 JBrowse link NW_004936495 11,111,247 11,121,976 RGD:9068941
cellular detoxification of nitrogen compound term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gstm3 glutathione S-transferase mu 3 JBrowse link NW_004936704 1,233,909 1,236,864 RGD:9068941
cellular oxidant detoxification term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Alox5ap arachidonate 5-lipoxygenase activating protein JBrowse link NW_004936472 25,477,094 25,502,823 RGD:9068941
G Apoe apolipoprotein E JBrowse link NW_004936706 1,512,438 1,516,805 RGD:9068941
G Apom apolipoprotein M JBrowse link NW_004936727 1,868,751 1,874,347 RGD:9068941
G Cat catalase JBrowse link NW_004936533 3,601,270 3,637,128 RGD:9068941
G Clic2 chloride intracellular channel 2 JBrowse link NW_004936927 514,989 543,691 RGD:9068941
G Cygb cytoglobin JBrowse link NW_004936594 1,602,436 1,613,783 RGD:9068941
G Duox1 dual oxidase 1 JBrowse link NW_004936471 7,848,472 7,881,417 RGD:9068941
G Duox2 dual oxidase 2 JBrowse link NW_004936471 7,812,163 7,831,258 RGD:9068941
G Epx eosinophil peroxidase JBrowse link NW_004936490 4,876,857 4,887,275 RGD:9068941
G Fabp1 fatty acid binding protein 1 JBrowse link NW_004936712 738,361 743,073 RGD:9068941
G Gpx1 glutathione peroxidase 1 JBrowse link NW_004936529 997,943 999,123 RGD:9068941
G Gpx2 glutathione peroxidase 2 JBrowse link NW_004936495 8,590,225 8,593,511 RGD:9068941
G Gpx3 glutathione peroxidase 3 JBrowse link NW_004936647 3,904,787 3,914,223 RGD:9068941
G Gpx4 glutathione peroxidase 4 JBrowse link NW_004936588 506,101 508,469 RGD:9068941
G Gpx5 glutathione peroxidase 5 JBrowse link NW_004936914 487,163 496,465 RGD:9068941
G Gpx6 glutathione peroxidase 6 JBrowse link NW_004936914 535,324 543,114 RGD:9068941
G Gpx7 glutathione peroxidase 7 JBrowse link NW_004936522 8,381,678 8,388,800 RGD:9068941
G Gpx8 glutathione peroxidase 8 (putative) JBrowse link NW_004936480 12,600,010 12,604,411 RGD:9068941
G Gsr glutathione-disulfide reductase JBrowse link NW_004936792 531,076 579,083 RGD:9068941
G Gstk1 glutathione S-transferase kappa 1 JBrowse link NW_004936527 722,548 727,169 RGD:9068941
G Gsto1 glutathione S-transferase omega 1 JBrowse link NW_004936600 1,932,152 1,943,342 RGD:9068941
G Gsto2 glutathione S-transferase omega 2 JBrowse link NW_004936600 1,907,396 1,925,256 RGD:9068941
G Gstp1 glutathione S-transferase pi 1 JBrowse link NW_004936599 2,197,681 2,200,642 RGD:9068941
G Gstz1 glutathione S-transferase zeta 1 JBrowse link NW_004936488 6,141,913 6,153,591 RGD:9068941
G Hbe1 hemoglobin subunit epsilon 1 JBrowse link NW_004937116 173,006 174,535 RGD:9068941
G Hbq1 hemoglobin subunit theta 1 JBrowse link NW_004936501 725,485 726,477 RGD:9068941
G Ipcef1 interaction protein for cytohesin exchange factors 1 JBrowse link NW_004936489 6,595,905 6,662,509 RGD:9068941
G Iyd iodotyrosine deiodinase JBrowse link NW_004936489 3,454,757 3,472,423 RGD:9068941
G Kdm3b lysine demethylase 3B JBrowse link NW_004936531 7,517,810 7,600,319 RGD:9068941
G LOC101976500 haptoglobin JBrowse link NW_004936475 21,841,054 21,845,821 RGD:9068941
G Loxhd1 lipoxygenase homology domains 1 JBrowse link NW_004936517 271,909 409,818 RGD:9068941
G Lpo lactoperoxidase JBrowse link NW_004936490 4,821,421 4,838,377 RGD:9068941
G Ltc4s leukotriene C4 synthase JBrowse link NW_004936739 975,494 978,426 RGD:9068941
G Mgst1 microsomal glutathione S-transferase 1 JBrowse link NW_004936587 1,270,030 1,287,130 RGD:9068941
G Mgst2 microsomal glutathione S-transferase 2 JBrowse link NW_004936535 7,995,185 8,015,463 RGD:9068941
G Mgst3 microsomal glutathione S-transferase 3 JBrowse link NW_004936481 19,654,335 19,665,994 RGD:9068941
G Mpo myeloperoxidase JBrowse link NW_004936490 4,809,773 4,819,070 RGD:9068941
G Nnt nicotinamide nucleotide transhydrogenase JBrowse link NW_004936480 18,599,037 18,692,097 RGD:9068941
G Nxn nucleoredoxin JBrowse link NW_004936538 6,966,296 6,995,691 RGD:9068941
G Park7 Parkinsonism associated deglycase JBrowse link NW_004936623 2,422,780 2,436,817 RGD:9068941
G Prdx1 peroxiredoxin 1 JBrowse link NW_004936474 26,641,776 26,653,291 RGD:9068941
G Prdx2 peroxiredoxin 2 JBrowse link NW_004936659 1,894,423 1,897,690 RGD:9068941
G Prdx3 peroxiredoxin 3 JBrowse link NW_004936486 8,597,479 8,606,727 RGD:9068941
G Prdx4 peroxiredoxin 4 JBrowse link NW_004936624 859,281 873,784 RGD:9068941
G Prdx5 peroxiredoxin 5 JBrowse link NW_004936599 4,894,409 4,897,426 RGD:9068941
G Prdx6 peroxiredoxin 6 JBrowse link NW_004936481 14,223,422 14,233,634 RGD:9068941
G Prxl2a peroxiredoxin like 2A JBrowse link NW_004936716 246,735 266,513 RGD:9068941
G Prxl2b peroxiredoxin like 2B JBrowse link NW_004936737 998,313 1,000,757 RGD:9068941
G Prxl2c peroxiredoxin like 2C JBrowse link NW_004936487 551,072 564,688 RGD:9068941
G Ptgs1 prostaglandin-endoperoxide synthase 1 JBrowse link NW_004936487 10,745,465 10,758,812 RGD:9068941
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link NW_004936481 3,821,564 3,828,086 RGD:9068941
G Pxdn peroxidasin JBrowse link NW_004936532 462,507 543,549 RGD:9068941
G Pxdnl peroxidasin like JBrowse link NW_004936590 1,059,538 1,496,199 RGD:9068941
G Rp1 RP1 axonemal microtubule associated JBrowse link NW_004936496 1,396,838 1,411,082 RGD:9068941
G S100a9 S100 calcium binding protein A9 JBrowse link NW_004936580 3,228,097 3,230,652 RGD:9068941
G Selenos selenoprotein S JBrowse link NW_004936483 2,589,773 2,600,837 RGD:9068941
G Selenot selenoprotein T JBrowse link NW_004936758 1,001,452 1,023,582 RGD:9068941
G Selenow selenoprotein W JBrowse link NW_004936664 1,358,753 1,361,112 RGD:9068941
G Sesn1 sestrin 1 JBrowse link NW_004936564 5,187,152 5,291,201 RGD:9068941
G Sesn2 sestrin 2 JBrowse link NW_004936474 12,416,652 12,436,799 RGD:9068941
G Srxn1 sulfiredoxin 1 JBrowse link NW_004936485 17,873,283 17,879,746 RGD:9068941
G Tp53inp1 tumor protein p53 inducible nuclear protein 1 JBrowse link NW_004936544 7,882,710 7,891,668 RGD:9068941
G Tpo thyroid peroxidase JBrowse link NW_004936532 391,181 435,132 RGD:9068941
G Txn thioredoxin JBrowse link NW_004936559 2,811,786 2,822,528 RGD:9068941
G Txndc17 thioredoxin domain containing 17 JBrowse link NW_004936677 1,352,233 1,354,576 RGD:9068941
G Txndc2 thioredoxin domain containing 2 JBrowse link NW_004936626 1,608,877 1,610,472 RGD:9068941
G Txnrd1 thioredoxin reductase 1 JBrowse link NW_004936492 10,185,096 10,244,466 RGD:9068941
G Txnrd2 thioredoxin reductase 2 JBrowse link NW_004936619 3,789,940 3,847,286 RGD:9068941
G Txnrd3 thioredoxin reductase 3 JBrowse link NW_004936798 1,190,975 1,231,732 RGD:9068941
G Ubiad1 UbiA prenyltransferase domain containing 1 JBrowse link NW_004936474 284,630 293,090 RGD:9068941
detoxification of cadmium ion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Slc30a1 solute carrier family 30 member 1 JBrowse link NW_004936557 1,789,263 1,796,548 RGD:9068941
detoxification of copper ion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atp7a ATPase copper transporting alpha JBrowse link NW_004936683 2,874,022 2,936,214 RGD:9068941
G Mt3 metallothionein 3 JBrowse link NW_004936475 8,864,512 8,866,516 RGD:9068941
G Mt4 metallothionein 4 JBrowse link NW_004936475 8,842,863 8,845,105 RGD:9068941
G Park7 Parkinsonism associated deglycase JBrowse link NW_004936623 2,422,780 2,436,817 RGD:9068941
detoxification of mercury ion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Park7 Parkinsonism associated deglycase JBrowse link NW_004936623 2,422,780 2,436,817 RGD:9068941
detoxification of nitrogen compound term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G LOC101974965 mitochondrial amidoxime reducing component 2 JBrowse link NW_004936650 1,506,471 1,543,532 RGD:9068941
G Marc1 mitochondrial amidoxime reducing component 1 JBrowse link NW_004936650 1,477,138 1,504,501 RGD:9068941
formaldehyde catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Esd esterase D JBrowse link NW_004936565 285,789 309,390 RGD:9068941
guanine deglycation, methylglyoxal removal term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Park7 Parkinsonism associated deglycase JBrowse link NW_004936623 2,422,780 2,436,817 RGD:9068941
phenylacetate catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pon3 paraoxonase 3 JBrowse link NW_004936585 4,902,430 4,928,377 RGD:9068941
positive regulation of superoxide dismutase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Park7 Parkinsonism associated deglycase JBrowse link NW_004936623 2,422,780 2,436,817 RGD:9068941
G Rgn regucalcin JBrowse link NW_004936502 12,872,938 12,891,270 RGD:9068941
G Tnf tumor necrosis factor JBrowse link NW_004936727 1,936,066 1,937,766 RGD:9068941
regulation of removal of superoxide radicals term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmp7 bone morphogenetic protein 7 JBrowse link NW_004936530 71,965 143,940 RGD:9068941
G Cd36 CD36 molecule JBrowse link NW_004936810 791,823 838,303 RGD:9068941
G Dhfr dihydrofolate reductase JBrowse link NW_004936469 67,962 83,116 RGD:9068941
G Fbln5 fibulin 5 JBrowse link NW_004936733 136,374 200,106 RGD:9068941
G Gch1 GTP cyclohydrolase 1 JBrowse link NW_004936697 232,048 275,420 RGD:9068941
G Nfe2l2 nuclear factor, erythroid 2 like 2 JBrowse link NW_004936509 6,589,967 6,621,171 RGD:9068941
regulation of superoxide dismutase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Szt2 SZT2 subunit KICSTOR complex JBrowse link NW_004936474 24,788,175 24,837,471 RGD:9068941
removal of superoxide radicals term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Apoa4 apolipoprotein A4 JBrowse link NW_004936542 2,098,683 2,101,127 RGD:9068941
G Atp7a ATPase copper transporting alpha JBrowse link NW_004936683 2,874,022 2,936,214 RGD:9068941
G Ccs copper chaperone for superoxide dismutase JBrowse link NW_004936599 2,992,740 3,005,230 RGD:9068941
G Fancc FA complementation group C JBrowse link NW_004936626 3,980,311 4,147,042 RGD:9068941
G Mpo myeloperoxidase JBrowse link NW_004936490 4,809,773 4,819,070 RGD:9068941
G Mt3 metallothionein 3 JBrowse link NW_004936475 8,864,512 8,866,516 RGD:9068941
G Nos3 nitric oxide synthase 3 JBrowse link NW_004936527 6,427,147 6,445,770 RGD:9068941
G Nqo1 NAD(P)H quinone dehydrogenase 1 JBrowse link NW_004936475 19,771,384 19,785,034 RGD:9068941
G Prdx1 peroxiredoxin 1 JBrowse link NW_004936474 26,641,776 26,653,291 RGD:9068941
G Prdx2 peroxiredoxin 2 JBrowse link NW_004936659 1,894,423 1,897,690 RGD:9068941
G Sod1 superoxide dismutase 1 JBrowse link NW_004936500 10,345,154 10,352,873 RGD:9068941
G Sod2 superoxide dismutase 2 JBrowse link NW_004936489 11,178,338 11,191,601 RGD:9068941

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 14762
    detoxification 98
      cellular detoxification + 93
      cellular detoxification of methylglyoxal + 1
      detoxification of arsenic-containing substance 0
      detoxification of inorganic compound + 5
      detoxification of nitrogen compound + 3
      detoxification of zinc ion 0
      mycothiol-dependent detoxification 0
      toxin catabolic process + 2
Path 2
Term Annotations click to browse term
  biological_process 14762
    response to stimulus 7729
      response to chemical 3974
        response to toxic substance 467
          detoxification 98
            cellular detoxification + 93
            cellular detoxification of methylglyoxal + 1
            detoxification of arsenic-containing substance 0
            detoxification of inorganic compound + 5
            detoxification of nitrogen compound + 3
            detoxification of zinc ion 0
            mycothiol-dependent detoxification 0
            toxin catabolic process + 2
paths to the root