ONTOLOGY REPORT - ANNOTATIONS


Term:modulation of excitatory postsynaptic potential
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Accession:GO:0098815 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of excitatory postsynaptic potential (EPSP). EPSP is a process that leads to a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential.


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modulation of excitatory postsynaptic potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G App amyloid beta precursor protein JBrowse link 11 24,425,013 24,641,872 RGD:1624291
RGD:1600115
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit JBrowse link 1 123,897,341 124,039,263 RGD:1624291
G Sh3gl1 SH3 domain containing GRB2 like 1, endophilin A2 JBrowse link 9 11,031,847 11,055,285 RGD:13463484
G Stx1a syntaxin 1A JBrowse link 12 24,682,050 24,710,002 RGD:11535099
G Tmem108 transmembrane protein 108 JBrowse link 8 111,968,568 112,265,623 RGD:1624291
G Zmynd8 zinc finger, MYND-type containing 8 JBrowse link 3 162,480,766 162,594,145 RGD:8554267
negative regulation of excitatory postsynaptic potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cbln1 cerebellin 1 precursor JBrowse link 19 20,607,507 20,611,316 RGD:1624291
RGD:1600115
G Celf4 CUGBP, Elav-like family member 4 JBrowse link 18 17,689,090 18,079,835 RGD:1624291
G Eif4a3 eukaryotic translation initiation factor 4A3 JBrowse link 10 108,415,201 108,425,195 RGD:10044262
G Lrrk2 leucine-rich repeat kinase 2 JBrowse link 7 132,857,311 133,018,549 RGD:1624291
RGD:1600115
G Mtmr2 myotubularin related protein 2 JBrowse link 8 12,283,471 12,334,014 RGD:8553482
G Nlgn3 neuroligin 3 JBrowse link X 71,199,390 71,227,460 RGD:1624291
RGD:1600115
G Npy2r neuropeptide Y receptor Y2 JBrowse link 2 181,528,949 181,538,145 RGD:1642608
G Prkn parkin RBR E3 ubiquitin protein ligase JBrowse link 1 48,880,015 50,069,998 RGD:10413844
G Pten phosphatase and tensin homolog JBrowse link 1 251,421,814 251,487,634 RGD:1624291
RGD:1600115
G S1pr2 sphingosine-1-phosphate receptor 2 JBrowse link 8 21,984,914 21,995,806 RGD:1624291
RGD:1600115
negative regulation of mini excitatory postsynaptic potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Syne1 spectrin repeat containing nuclear envelope protein 1 JBrowse link 1
1
41,608,287
41,844,840
41,763,591
42,086,662
RGD:13209020
positive regulation of excitatory postsynaptic potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Baiap2 BAI1-associated protein 2 JBrowse link 10 109,107,326 109,187,458 RGD:9684984
G Cacnb3 calcium voltage-gated channel auxiliary subunit beta 3 JBrowse link 7 140,311,120 140,324,902 RGD:13514092
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit JBrowse link 1 123,897,341 124,039,263 RGD:1600115
RGD:1624291
G Cux2 cut-like homeobox 2 JBrowse link 12 40,016,774 40,221,067 RGD:1624291
RGD:1600115
G Dbn1 drebrin 1 JBrowse link 17 9,679,511 9,693,878 RGD:10398809
G Dlg4 discs large MAGUK scaffold protein 4 JBrowse link 10 56,625,845 56,655,543 RGD:8554754
G Drd4 dopamine receptor D4 JBrowse link 1 214,278,296 214,282,818 RGD:7248611
G Dvl1 dishevelled segment polarity protein 1 JBrowse link 5 173,295,948 173,308,014 RGD:10449514
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 JBrowse link 3 2,507,745 2,534,664 RGD:8554754
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A JBrowse link 10 5,707,806 6,123,568 RGD:8554754
G Grip2 glutamate receptor interacting protein 2 JBrowse link 4 123,585,184 123,636,040 RGD:4107359
G Grk2 G protein-coupled receptor kinase 2 JBrowse link 1 219,536,220 219,544,329 RGD:13506836
G Gsk3b glycogen synthase kinase 3 beta JBrowse link 11 65,060,884 65,208,842 RGD:4107027
G Neto1 neuropilin and tolloid like 1 JBrowse link 18 83,471,342 83,585,043 RGD:1624291
RGD:1600115
G Neto2 neuropilin and tolloid like 2 JBrowse link 19 22,450,579 22,486,530 RGD:1624291
G Ngfr nerve growth factor receptor JBrowse link 10 83,389,828 83,408,061 RGD:10414080
G Nlgn1 neuroligin 1 JBrowse link 2 111,057,291 111,973,681 RGD:8553502
RGD:1624291
RGD:8554379
RGD:8554760
G Nlgn2 neuroligin 2 JBrowse link 10 56,431,586 56,444,847 RGD:1624291
RGD:1600115
G Nlgn3 neuroligin 3 JBrowse link X 71,199,390 71,227,460 RGD:1624291
RGD:1600115
G Nrxn1 neurexin 1 JBrowse link 6 13,886,757 15,191,660 RGD:1600115
RGD:1624291
G Prkcz protein kinase C, zeta JBrowse link 5 172,658,071 172,769,492 RGD:8554098
G Pten phosphatase and tensin homolog JBrowse link 1 251,421,814 251,487,634 RGD:1624291
RGD:1600115
G Ptk2b protein tyrosine kinase 2 beta JBrowse link 15 42,827,306 42,947,796 RGD:8553497
G Reln reelin JBrowse link 4 9,347,533 9,774,257 RGD:1600115
RGD:1624291
G Rgs4 regulator of G-protein signaling 4 JBrowse link 13 88,054,817 88,061,108 RGD:13524537
G Rims1 regulating synaptic membrane exocytosis 1 JBrowse link 9 28,440,408 28,973,246 RGD:1624291
RGD:1600115
G Rims2 regulating synaptic membrane exocytosis 2 JBrowse link 7 78,091,998 78,594,164 RGD:1624291
RGD:1600115
G Shank1 SH3 and multiple ankyrin repeat domains 1 JBrowse link 1 100,297,137 100,344,377 RGD:1624291
RGD:13792537
RGD:1600115
G Shank2 SH3 and multiple ankyrin repeat domains 2 JBrowse link 1 217,149,156 217,593,950 RGD:13792537
G Shank3 SH3 and multiple ankyrin repeat domains 3 JBrowse link 7 130,474,278 130,534,679 RGD:1600115
RGD:13792537
RGD:1624291
RGD:7349315
G Ssh1 slingshot protein phosphatase 1 JBrowse link 12 48,403,184 48,447,964 RGD:11535133
G Stx1a syntaxin 1A JBrowse link 12 24,682,050 24,710,002 RGD:1624291
RGD:1600115
G Stx1b syntaxin 1B JBrowse link 1 199,251,842 199,270,465 RGD:1624291
RGD:1600115
G Tbc1d24 TBC1 domain family, member 24 JBrowse link 10 13,551,100 13,576,739 RGD:11537391
G Wnt7a Wnt family member 7A JBrowse link 4 122,994,425 123,040,609 RGD:1624291
RGD:1600115
positive regulation of mini excitatory postsynaptic potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adrb2 adrenoceptor beta 2 JBrowse link 18 57,513,792 57,515,834 RGD:1600115
RGD:1624291
G Afdn afadin, adherens junction formation factor JBrowse link 1 53,713,873 53,861,918 RGD:13838731
G Igsf11 immunoglobulin superfamily, member 11 JBrowse link 11 64,286,691 64,421,248 RGD:11085699
regulation of acetylcholine-gated cation channel activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Chrna4 cholinergic receptor nicotinic alpha 4 subunit JBrowse link 3 176,533,182 176,547,965 RGD:704387
regulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bscl2 BSCL2 lipid droplet biogenesis associated, seipin JBrowse link 1 225,035,956 225,046,137 RGD:1624291
G Dmpk DM1 protein kinase JBrowse link 1 79,988,096 79,999,358 RGD:1624291
RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17941
    cellular process 16091
      signal transduction 6515
        regulation of signal transduction 2851
          modulation of excitatory postsynaptic potential 54
            negative regulation of excitatory postsynaptic potential + 11
            positive regulation of excitatory postsynaptic potential + 38
            regulation of acetylcholine-gated cation channel activity + 1
            regulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction 2
            regulation of mini excitatory postsynaptic potential + 4
Path 2
Term Annotations click to browse term
  biological_process 17941
    cellular process 16091
      cell communication 7118
        cell-cell signaling 1616
          synaptic signaling 880
            trans-synaptic signaling 860
              anterograde trans-synaptic signaling 851
                chemical synaptic transmission 851
                  chemical synaptic transmission, postsynaptic 121
                    excitatory postsynaptic potential 112
                      modulation of excitatory postsynaptic potential 54
                        negative regulation of excitatory postsynaptic potential + 11
                        positive regulation of excitatory postsynaptic potential + 38
                        regulation of acetylcholine-gated cation channel activity + 1
                        regulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction 2
                        regulation of mini excitatory postsynaptic potential + 4
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.