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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of bundle of His cell action potential
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Accession:GO:0098905 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a cardiac muscle cell of the bundle of His. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.
Synonyms:exact_synonym: regulation of bundle of His cardiac muscle cell action potential


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regulation of bundle of His cell action potential term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gja5 gap junction protein, alpha 5 ISO (PMID:22247482)
(MGI:MGI:3696497|PMID:10515563)
RGD PMID:10515563, PMID:22247482 MGI:MGI:3696497 NCBI chr 2:199,162,745...199,184,942
Ensembl chr 2:199,162,745...199,184,939
JBrowse link
G Rangrf RAN guanine nucleotide release factor ISO (PMID:21621375) RGD PMID:21621375 NCBI chr10:55,559,049...55,560,420
Ensembl chr10:55,559,041...55,560,422
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20028
    regulation of biological process 13075
      regulation of action potential 66
        regulation of cardiac muscle cell action potential 28
          regulation of bundle of His cell action potential 2
Path 2
Term Annotations click to browse term
  biological_process 20028
    multicellular organismal process 9046
      system process 3453
        circulatory system process 579
          heart process 255
            heart contraction 246
              regulation of heart contraction 199
                cardiac conduction 66
                  cell communication involved in cardiac conduction 41
                    bundle of His cell to Purkinje myocyte communication 16
                      bundle of His cell to Purkinje myocyte signaling 7
                        bundle of His cell action potential 7
                          regulation of bundle of His cell action potential 2
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.