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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of ventricular cardiac muscle cell action potential
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Accession:GO:0098911 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a ventricular cardiac muscle cell contributing to the regulation of its contraction. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.


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regulation of ventricular cardiac muscle cell action potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AABR07034767.1 RGD:1600115
G AABR07044900.1 RGD:1600115
G Cacna1c calcium voltage-gated channel subunit alpha1 C JBrowse link 4 150,635,808 151,270,790 RGD:1600115
RGD:1624291
G Cav1 caveolin 1 JBrowse link 4 44,597,123 44,630,206 RGD:1624291
RGD:1600115
G Ctnna3 catenin alpha 3 JBrowse link 20 25,063,124 26,640,428 RGD:1624291
G Dlg1 discs large MAGUK scaffold protein 1 JBrowse link 11 72,164,566 72,378,895 RGD:1624291
G Dsc2 desmocollin 2 JBrowse link 18 11,826,705 11,858,801 RGD:1624291
G Dsg2 desmoglein 2 JBrowse link 18 15,579,322 15,637,720 RGD:1624291
G Dsp desmoplakin JBrowse link 17 27,286,811 27,334,453 RGD:1624291
G Jup junction plakoglobin JBrowse link 10 88,280,517 88,307,451 RGD:1624291
G Pkp2 plakophilin 2 JBrowse link 11 88,912,163 88,972,213 RGD:1624291
G Ryr2 ryanodine receptor 2 JBrowse link 17 65,533,998 65,955,606 RGD:1624291
RGD:1600115
G Trpm4 transient receptor potential cation channel, subfamily M, member 4 JBrowse link 1 101,293,300 101,323,484 RGD:1600115
RGD:1624291
negative regulation of membrane repolarization during ventricular cardiac muscle cell action potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Kcne3 potassium voltage-gated channel subfamily E regulatory subunit 3 JBrowse link 1 165,189,934 165,196,949 RGD:1624291
negative regulation of ventricular cardiac muscle cell action potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bin1 bridging integrator 1 JBrowse link 18 25,163,575 25,222,139 RGD:1600115
RGD:1624291
positive regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Rnf207 ring finger protein 207 JBrowse link 5 169,486,253 169,500,451 RGD:1624291
regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dlg1 discs large MAGUK scaffold protein 1 JBrowse link 11 72,164,566 72,378,895 RGD:1600115
RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19858
    regulation of biological process 12958
      regulation of action potential 66
        regulation of cardiac muscle cell action potential 30
          regulation of ventricular cardiac muscle cell action potential 16
            negative regulation of ventricular cardiac muscle cell action potential + 2
            positive regulation of ventricular cardiac muscle cell action potential + 1
            regulation of membrane repolarization during ventricular cardiac muscle cell action potential + 3
Path 2
Term Annotations click to browse term
  biological_process 19858
    biological regulation 13635
      regulation of biological process 12958
        regulation of multicellular organismal process 3442
          regulation of system process 652
            regulation of muscle system process 268
              regulation of muscle contraction 170
                regulation of striated muscle contraction 92
                  regulation of cardiac muscle contraction 78
                    regulation of cardiac muscle cell contraction 43
                      regulation of ventricular cardiac muscle cell action potential 16
                        negative regulation of ventricular cardiac muscle cell action potential + 2
                        positive regulation of ventricular cardiac muscle cell action potential + 1
                        regulation of membrane repolarization during ventricular cardiac muscle cell action potential + 3
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.