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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of ventricular cardiac muscle cell action potential
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Accession:GO:0098911 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a ventricular cardiac muscle cell contributing to the regulation of its contraction. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.


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regulation of ventricular cardiac muscle cell action potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cacna1c calcium voltage-gated channel subunit alpha1 C JBrowse link NW_004955454 4,573,647 5,199,046 RGD:9068941
G Cav1 caveolin 1 JBrowse link NW_004955432 22,258,262 22,292,403 RGD:9068941
G Ctnna3 catenin alpha 3 JBrowse link NW_004955425 18,623,645 20,126,200 RGD:9068941
G Dlg1 discs large MAGUK scaffold protein 1 JBrowse link NW_004955420 13,068,289 13,273,805 RGD:9068941
G Dsc2 desmocollin 2 JBrowse link NW_004955402 18,465,631 18,496,948 RGD:9068941
G Dsg2 desmoglein 2 JBrowse link NW_004955402 18,826,400 18,876,188 RGD:9068941
G Dsp desmoplakin JBrowse link NW_004955465 6,356,970 6,391,206 RGD:9068941
G Jup junction plakoglobin JBrowse link NW_004955451 15,993,055 16,004,152 RGD:9068941
G Pkp2 plakophilin 2 JBrowse link NW_004955505 2,878,001 2,959,299 RGD:9068941
G Ryr2 ryanodine receptor 2 JBrowse link NW_004955492 2,647,597 3,275,512 RGD:9068941
G Trpm4 transient receptor potential cation channel subfamily M member 4 JBrowse link NW_004955559 1,539,036 1,581,800 RGD:9068941
negative regulation of membrane repolarization during ventricular cardiac muscle cell action potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Kcne3 potassium voltage-gated channel subfamily E regulatory subunit 3 JBrowse link NW_004955414 17,166,537 17,200,385 RGD:9068941
negative regulation of ventricular cardiac muscle cell action potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bin1 bridging integrator 1 JBrowse link NW_004955459 3,376,149 3,423,157 RGD:9068941
regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dlg1 discs large MAGUK scaffold protein 1 JBrowse link NW_004955420 13,068,289 13,273,805 RGD:9068941

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 11828
    regulation of biological process 8228
      regulation of action potential 60
        regulation of cardiac muscle cell action potential 26
          regulation of ventricular cardiac muscle cell action potential 13
            negative regulation of ventricular cardiac muscle cell action potential + 2
            positive regulation of ventricular cardiac muscle cell action potential + 0
            regulation of membrane repolarization during ventricular cardiac muscle cell action potential + 2
Path 2
Term Annotations click to browse term
  biological_process 11828
    biological regulation 8664
      regulation of biological process 8228
        regulation of multicellular organismal process 3044
          regulation of system process 600
            regulation of muscle system process 251
              regulation of muscle contraction 156
                regulation of striated muscle contraction 84
                  regulation of cardiac muscle contraction 70
                    regulation of cardiac muscle cell contraction 38
                      regulation of ventricular cardiac muscle cell action potential 13
                        negative regulation of ventricular cardiac muscle cell action potential + 2
                        positive regulation of ventricular cardiac muscle cell action potential + 0
                        regulation of membrane repolarization during ventricular cardiac muscle cell action potential + 2
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.