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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of ventricular cardiac muscle cell action potential
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Accession:GO:0098911 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a ventricular cardiac muscle cell contributing to the regulation of its contraction. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.


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regulation of ventricular cardiac muscle cell action potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CACNA1C calcium voltage-gated channel subunit alpha1 C JBrowse link 27 44,007,363 44,748,251 RGD:13508589
G CAV1 caveolin 1 JBrowse link 14 55,458,934 55,494,563 RGD:13508589
G CTNNA3 catenin alpha 3 JBrowse link 4 17,364,121 19,035,836 RGD:13508589
G DLG1 discs large MAGUK scaffold protein 1 JBrowse link 33 30,016,323 30,253,180 RGD:9068941
G DSC2 desmocollin 2 JBrowse link 7 58,369,316 58,402,028 RGD:13508589
G DSG2 desmoglein 2 JBrowse link 7 57,981,918 58,030,197 RGD:9068941
G DSP desmoplakin JBrowse link 35 7,479,628 7,524,732 RGD:13508589
G JUP junction plakoglobin JBrowse link 9 21,028,773 21,053,071 RGD:13508589
G PKP2 plakophilin 2 JBrowse link 27 16,023,186 16,109,978 RGD:9068941
G RYR2 ryanodine receptor 2 JBrowse link 4 2,371,868 2,908,132 RGD:13508589
G TRPM4 transient receptor potential cation channel subfamily M member 4 JBrowse link 1 107,261,760 107,304,157 RGD:13508589
negative regulation of membrane repolarization during ventricular cardiac muscle cell action potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G KCNE3 potassium voltage-gated channel subfamily E regulatory subunit 3 JBrowse link 21 23,860,727 23,872,194 RGD:13508589
negative regulation of ventricular cardiac muscle cell action potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BIN1 bridging integrator 1 JBrowse link 19 23,503,934 23,534,407 RGD:9068941
positive regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G RNF207 ring finger protein 207 JBrowse link 5 60,105,200 60,119,902 RGD:13508589
regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G DLG1 discs large MAGUK scaffold protein 1 JBrowse link 33 30,016,323 30,253,180 RGD:9068941

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16043
    regulation of biological process 10828
      regulation of action potential 63
        regulation of cardiac muscle cell action potential 27
          regulation of ventricular cardiac muscle cell action potential 14
            negative regulation of ventricular cardiac muscle cell action potential + 2
            positive regulation of ventricular cardiac muscle cell action potential + 1
            regulation of membrane repolarization during ventricular cardiac muscle cell action potential + 3
Path 2
Term Annotations click to browse term
  biological_process 16043
    biological regulation 11410
      regulation of biological process 10828
        regulation of multicellular organismal process 3272
          regulation of system process 636
            regulation of muscle system process 261
              regulation of muscle contraction 163
                regulation of striated muscle contraction 88
                  regulation of cardiac muscle contraction 73
                    regulation of cardiac muscle cell contraction 39
                      regulation of ventricular cardiac muscle cell action potential 14
                        negative regulation of ventricular cardiac muscle cell action potential + 2
                        positive regulation of ventricular cardiac muscle cell action potential + 1
                        regulation of membrane repolarization during ventricular cardiac muscle cell action potential + 3
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.