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ONTOLOGY REPORT - ANNOTATIONS


Term:presynaptic dense core vesicle exocytosis
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Accession:GO:0099525 term browser browse the term
Definition:The secretion of molecules (e.g. neuropeptides and neuromodulators such as serotonin and dopamine) contained within a membrane-bounced dense in response to increased presynaptic cytosolic calcium levels.


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presynaptic dense core vesicle exocytosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cadps calcium dependent secretion activator JBrowse link 15 15,275,489 15,690,575 RGD:1600115
RGD:1624291
G Stxbp1 syntaxin binding protein 1 JBrowse link 3 11,823,779 11,885,479 RGD:1624291
G Syt6 synaptotagmin 6 JBrowse link 2 206,064,181 206,119,034 RGD:13702162
G Unc13a unc-13 homolog A JBrowse link 16 20,056,398 20,103,951 RGD:1600115
RGD:13792537
RGD:1624291
G Unc13b unc-13 homolog B JBrowse link 5 58,505,449 58,714,396 RGD:1624291
RGD:13792537
G Unc13c unc-13 homolog C JBrowse link 8 80,202,736 80,656,363 RGD:13792537
regulation of presynaptic dense core granule exocytosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G P2rx7 purinergic receptor P2X 7 JBrowse link 12 39,353,613 39,396,042 RGD:13702177
G Syt4 synaptotagmin 4 JBrowse link 18 24,172,580 24,181,989 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19335
    biological regulation 13337
      regulation of biological quality 4238
        regulation of neurotransmitter levels 409
          neurotransmitter secretion 209
            synaptic vesicle exocytosis 158
              calcium ion-regulated exocytosis of neurotransmitter 27
                presynaptic dense core vesicle exocytosis 8
                  neuropeptide secretion from presynapse 0
                  regulation of presynaptic dense core granule exocytosis 2
Path 2
Term Annotations click to browse term
  biological_process 19335
    cellular process 17239
      cell communication 7545
        cell-cell signaling 1888
          synaptic signaling 899
            trans-synaptic signaling 876
              anterograde trans-synaptic signaling 867
                chemical synaptic transmission 867
                  neurotransmitter secretion 209
                    synaptic vesicle exocytosis 158
                      calcium ion-regulated exocytosis of neurotransmitter 27
                        presynaptic dense core vesicle exocytosis 8
                          neuropeptide secretion from presynapse 0
                          regulation of presynaptic dense core granule exocytosis 2
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.